Integrating multiple omics data for the discovery of potential Beclin-1 interactions in breast cancer

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Integrating multiple omics data for the discovery of potential Beclin-1 interactions in breast cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/C6MB00653A
P698PubMed publication ID28401970

P2093author name stringJun He
Xuan Wang
Shu Zhang
Yi Chen
Zhong Cheng
Guan Wang
Jinjin Wang
Lingyu Huang
Xiang Yuan
Zhaozhi Li
Yiqiong Yin
Ziyi Qin
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Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiaeQ27940093
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21Q28138953
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesisQ29617725
Autophagic effect of programmed cell death 5 (PDCD5) after focal cerebral ischemic reperfusion injury in rats.Q30774139
Integration and comparison of different genomic data for outcome prediction in cancer.Q31013326
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Simultaneous analysis of distinct Omics data sets with integration of biological knowledge: Multiple Factor Analysis approachQ33401075
Role of autophagy in breast cancerQ33808483
Combining multidimensional genomic measurements for predicting cancer prognosis: observations from TCGA.Q35221326
Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated with Estrogen Receptor-Negative Subtypes and Poor Prognosis.Q35223716
Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancerQ35740070
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Identification of ULK1 as a novel biomarker involved in miR-4487 and miR-595 regulation in neuroblastoma SH-SY5Y cell autophagyQ35860240
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.Q36111722
Integrating genetic association, genetics of gene expression, and single nucleotide polymorphism set analysis to identify susceptibility Loci for type 2 diabetes mellitusQ36402184
Molecular characterization of basal-like and non-basal-like triple-negative breast cancerQ36630430
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Beclin-1: autophagic regulator and therapeutic target in cancerQ38082656
Deciphering the complex: methodological overview of statistical models to derive OMICS-based biomarkersQ38126836
The use of principal component analysis and discriminant analysis in differential sensing routinesQ38133365
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Unraveling the roles of Atg4 proteases from autophagy modulation to targeted cancer therapyQ38709994
Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer TherapyQ38881119
AMBRA1 and BECLIN 1 interplay in the crosstalk between autophagy and cell proliferationQ38895769
The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cellsQ39149568
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradationQ39678666
Mechanistic study of TRPM2-Ca(2+)-CAMK2-BECN1 signaling in oxidative stress-induced autophagy inhibitionQ39721297
The BECN1 N-terminal domain is intrinsically disorderedQ40326289
BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondriaQ41166658
The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cellsQ41948789
Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetesQ42477947
Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.Q52942542
ADRB2 signaling promotes HCC progression and sorafenib resistance by inhibiting autophagic degradation of HIF1α.Q53106081
Integrated genetic and epigenetic analysis of bladder cancer reveals an additive diagnostic value of FGFR3 mutations and hypermethylation events.Q54651233
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)991-999
P577publication date2017-04-12
P1433published inMolecular BioSystemsQ3319467
P1476titleIntegrating multiple omics data for the discovery of potential Beclin-1 interactions in breast cancer
P478volume13

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cites work (P2860)
Q97519668Construction of a Comprehensive Multiomics Map of Hepatocellular Carcinoma and Screening of Possible Driver Genes
Q64082786Downregulation of CYB5D2 is associated with breast cancer progression
Q64079239Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy
Q47771300Stryphnodendron adstringens ("Barbatimão") Leaf Fraction: Chemical Characterization, Antioxidant Activity, and Cytotoxicity Towards Human Breast Cancer Cell Lines.
Q58769452What We Learned From Big Data for Autophagy Research

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