Role of NeuroD1 on the negative regulation of Pomc expression by glucocorticoid

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Role of NeuroD1 on the negative regulation of Pomc expression by glucocorticoid is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0175435
P932PMC publication ID5391015
P698PubMed publication ID28406939

P2093author name stringKyoko Shimizu
Ken Fujiwara
Akira Sugawara
Atsushi Yokoyama
Akiko Saito-Hakoda
Yasumasa Iwasaki
Rehana Parvin
Erika Noro
Hiroki Shimada
P2860cites workHelix-loop-helix proteins: regulators of transcription in eucaryotic organismsQ24554353
NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin geneQ24644235
Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cellsQ24644489
60 YEARS OF POMC: Transcriptional and epigenetic regulation of POMC gene expressionQ26770534
A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteinsQ28210920
Gene regulation by the glucocorticoid receptor: structure:function relationshipQ28248786
Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3Q28506870
Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcriptionQ28507962
Transcriptional regulation of mouse type 1 inositol 1,4,5-trisphosphate receptor gene by NeuroD-related factorQ28510379
The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cellsQ28512414
Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activationQ28513661
NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampusQ28584879
Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systemsQ29026493
Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix proteinQ29618504
Differential regulation of the glucagon and insulin I gene promoters by the basic helix-loop-helix transcription factors E47 and BETA2.Q32048256
Effects of mycophenolate mofetil, valsartan and their combined therapy on preventing podocyte loss in early stage of diabetic nephropathy in rats.Q33290524
Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.Q33301684
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.Q33929803
The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein bindingQ33957229
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.Q33963287
Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx familyQ33964485
Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.Q34040999
Stress Hormones: Their Interaction and RegulationQ34248023
Orphan nuclear receptor Nur77 regulates androgen receptor gene expression in mouse ovaryQ34326672
Diabetes mellitus and genetically programmed defects in beta-cell functionQ34462316
Identification of the DNA binding site for NGFI-B by genetic selection in yeastQ34955524
Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a nonfunctional stateQ70119499
Glucocorticoid regulation of pro-opiomelanocortin gene transcription in the rat pituitaryQ70811580
Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.Q35105992
Glucocorticoids in clinical oncologyQ35158664
Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression.Q35880635
Negative glucocorticoid receptor response elements and their role in glucocorticoid actionQ35892898
Human lymphocyte production of corticotropin and endorphin-like substances: association with leukocyte interferonQ36383046
Transcription factors regulating beta-cell functionQ36633890
Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin geneQ36678585
Pituitary pro-opiomelanocortin gene expression requires synergistic interactions of several regulatory elementsQ36724603
Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcriptionQ36797058
Tissue-specific activity of the pro-opiomelanocortin gene promoterQ36923897
Regulation of proopiomelanocortin gene expression: an overview of the signaling cascades, transcription factors, and responsive elements involvedQ37490013
Xebf3 is a regulator of neuronal differentiation during primary neurogenesis in Xenopus.Q38301179
NF-kappaB participates in the corticotropin-releasing, hormone-induced regulation of the pituitary proopiomelanocortin geneQ38346196
Moderate Exercise Prevents Functional Remodeling of the Anterior Pituitary Gland in Diet-Induced Insulin Resistance in Rats: Role of Oxidative Stress and AutophagyQ38811511
Retinoic acid receptor-α up-regulates proopiomelanocortin gene expression in AtT20 corticotroph cellsQ38965053
Corticotropin-releasing hormone or dexamethasone regulates rat proopiomelanocortin transcription through Tpit/Pitx-responsive element in its promoterQ40139075
Proopiomelanocortin-derived peptidesQ40559846
Post-translational processing of proopiomelanocortin in the pituitary and in the brainQ41419301
The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing.Q41578036
Effects of retinoic acid on growth hormone-releasing hormone receptor, growth hormone secretagogue receptor gene expression and growth hormone secretion in rat anterior pituitary cells.Q42491485
Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cellsQ43732050
Short term regulation of aldosterone secretion after stimulation and suppression experiments in miceQ43766315
Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation.Q47262544
BETA2 activates transcription from the upstream glucokinase gene promoter in islet beta-cells and gut endocrine cellsQ48404037
Opposite regulation of pro-opiomelanocortin gene transcription by glucocorticoids and CRH.Q48502493
Glucocorticoid regulation of hypothalamic proopiomelanocortinQ48521496
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)e0175435
P577publication date2017-04-13
P1433published inPLOS OneQ564954
P1476titleRole of NeuroD1 on the negative regulation of Pomc expression by glucocorticoid
P478volume12

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cites work (P2860)
Q55423757Inhibitory Effects of a Novel PPAR-γ Agonist MEKT1 on Pomc Expression/ACTH Secretion in AtT20 Cells.
Q54935905Prediction of Molecular Mechanisms for LianXia NingXin Formula: A Network Pharmacology Study.
Q88681571Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility

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