| scholarly article | Q13442814 |
| P50 | author | William Vainchenker | Q3569009 |
| Fawzia Louache | Q56155284 | ||
| Christophe Willekens | Q57058781 | ||
| Virginie Joulin | Q58214805 | ||
| Monika Wittner | Q58389915 | ||
| Eric Solary | Q41021747 | ||
| P2093 | author name string | Y Zhang | |
| M Ito | |||
| S Patel | |||
| F Pasquier | |||
| N Fujii | |||
| P Opolon | |||
| S Shen | |||
| P Gonin | |||
| P Coppo | |||
| S De Botton | |||
| O Bawa | |||
| A Betems | |||
| H Abdelouahab | |||
| P2860 | cites work | The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry | Q24315492 |
| Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4-/- chimeric mice. | Q53743494 | ||
| Identification of CXCR4 as a new nitric oxide-regulated gene in human CD34+ cells. | Q54577850 | ||
| Characterization of a hierarchy in human acute myeloid leukemia progenitor cells | Q71099942 | ||
| Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and Gαi proteins and enhances engraftment of competitive, repopulating stem cells | Q73316429 | ||
| Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist | Q73652781 | ||
| The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice | Q73827359 | ||
| Motility, proliferation, and egress to the circulation of human AML cells are elastase dependent in NOD/SCID chimeric mice | Q81823426 | ||
| Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice | Q24681021 | ||
| Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell | Q27861001 | ||
| A cell initiating human acute myeloid leukaemia after transplantation into SCID mice | Q28131777 | ||
| AMD3100: CXCR4 antagonist and rapid stem cell-mobilizing agent | Q28286940 | ||
| Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development | Q28512895 | ||
| The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1 | Q29616093 | ||
| Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches | Q29617460 | ||
| Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism. | Q33183348 | ||
| Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival. | Q33887787 | ||
| Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers | Q33979799 | ||
| Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis | Q34070556 | ||
| Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells | Q34246928 | ||
| High level engraftment of NOD/SCID mice by primitive normal and leukemic hematopoietic cells from patients with chronic myeloid leukemia in chronic phase. | Q34461470 | ||
| Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction | Q34772401 | ||
| Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide | Q34829342 | ||
| The therapeutic potential of CXCR4 antagonists in the treatment of HIV. | Q35056053 | ||
| A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia | Q35953355 | ||
| The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. | Q36376700 | ||
| Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. | Q37234638 | ||
| Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML. | Q37234641 | ||
| The leukemic stem cell niche: current concepts and therapeutic opportunities | Q37295129 | ||
| Update on clinical experience with AMD3100, an SDF-1/CXCL12-CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells | Q37753850 | ||
| A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection | Q39290210 | ||
| Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. | Q40528868 | ||
| CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice | Q40566210 | ||
| Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia | Q40571705 | ||
| Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines | Q40728781 | ||
| CXCR4 is required for the quiescence of primitive hematopoietic cells | Q42090614 | ||
| Loss of primitive hematopoietic progenitors in patients with human immunodeficiency virus infection | Q45765622 | ||
| Enhanced unique pattern of hematopoietic cell mobilization induced by the CXCR4 antagonist 4F-benzoyl-TN14003. | Q45868417 | ||
| CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow | Q47800956 | ||
| High expression of the chemokine receptor CXCR4 predicts extramedullary organ infiltration in childhood acute lymphoblastic leukaemia | Q48694724 | ||
| Intracellular localization and constitutive endocytosis of CXCR4 in human CD34+ hematopoietic progenitor cells. | Q50786871 | ||
| Stem cell gene expression programs influence clinical outcome in human leukemia. | Q51856192 | ||
| Leukaemia stem cells and the evolution of cancer-stem-cell research. | Q53302987 | ||
| MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. | Q53362332 | ||
| CXCR4 is a prognostic marker in acute myelogenous leukemia. | Q53607339 | ||
| P921 | main subject | leukemia | Q29496 |
| acute myeloid leukemia | Q264118 | ||
| P304 | page(s) | e396 | |
| P577 | publication date | 2012-10-04 | |
| P1433 | published in | Cell Death and Disease | Q2197222 |
| P1476 | title | CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model | |
| P478 | volume | 3 |
| Q91967489 | An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination |
| Q35836868 | Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy |
| Q38622918 | Are there any new insights for G-CSF and/or AMD3100 in chemotherapy of haematological malignants? |
| Q41553248 | CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner |
| Q38359714 | Cancer stem cells in haematological malignancies |
| Q91783057 | Combination of PET and CXCR4-Targeted Peptide Molecule Agents for Noninvasive Tumor Monitoring |
| Q36708959 | Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy. |
| Q37185272 | Dynamic chemotherapy-induced upregulation of CXCR4 expression: a mechanism of therapeutic resistance in pediatric AML. |
| Q58125348 | Engraftment of chronic myelomonocytic leukemia cells in immunocompromised mice supports disease dependency on cytokines |
| Q37191875 | Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia. |
| Q64103896 | In vitro and in vivo efficacy of an anti-CD203c conjugated antibody (AGS-16C3F) in mouse models of advanced systemic mastocytosis |
| Q33775283 | Inhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinoma |
| Q35949372 | Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies |
| Q57492451 | Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia |
| Q26746104 | Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality? |
| Q58596666 | Osteogenic niche in the regulation of normal hematopoiesis and leukemogenesis |
| Q38079235 | Role of CXCR4 in the pathogenesis of acute myeloid leukemia |
| Q49986947 | Role of the microenvironment in myeloid malignancies |
| Q91789449 | Significance of CXCL12/CXCR4 Ligand/Receptor Axis in Various Aspects of Acute Myeloid Leukemia |
| Q50002024 | TGF-β1 and CXCL12 modulate proliferation and chemotherapy sensitivity of acute myeloid leukemia cells co-cultured with multipotent mesenchymal stromal cells |
| Q41260777 | Targeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF-06747143). |
| Q37683451 | Targeting the CXCL12/CXCR4 axis in acute myeloid leukemia: from bench to bedside |
| Q45865484 | The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression |
| Q38167634 | The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets |
| Q85270672 | [Effects of SDF-1/CXCR4 signal pathway blockade by AMD3100 on the adhesion of leukemia cells to osteoblast niche and the drug resistance of leukemia cells] |
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