Three spontaneous H-2Db mutants are generated by genetic micro-recombination (gene conversion) events. Impact on the H-2-restricted immune responsiveness

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Three spontaneous H-2Db mutants are generated by genetic micro-recombination (gene conversion) events. Impact on the H-2-restricted immune responsiveness is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.168.6.2319
P932PMC publication ID2189132
P698PubMed publication ID3199070

P2093author name stringS G Nathenson
R A Zeff
R W Melvold
S Hemmi
J Geliebter
P2860cites workStructure of the human class I histocompatibility antigen, HLA-A2Q24297966
Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-CelluloseQ24563043
Genomic sequencingQ24594942
Detection of specific sequences among DNA fragments separated by gel electrophoresisQ25939003
Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNAQ29547801
The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigensQ33933458
Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primerQ35314314
Conservation and diversity in the class I genes of the major histocompatibility complex: sequence analysis of a Tlab gene and comparison with a Tlac geneQ35595164
Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6.Q35605598
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarityQ36270017
Exclusive involvement of H-2D(b) or H-2K(d) product in the interaction between T-killer lymphocytes and syngeneic H-2(b) or H-2(d) viral lymphomasQ36335910
Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotypeQ36341762
Immune response genes control T killer cell response against Moloney tumor antigen cytolysis regulating reactions against the best available H-2 + viral antigen associationQ36343656
Cytotoxic T lymphocyte nonresponsiveness to the male antigen H-Y in the H-2Db mutants bm13 and bm14. Complementation of the response in F1 crosses with the I-Ab mutant bm12 nonresponder and failure of B6 or Db mutant mice tolerant of each other to rQ36348150
Molecular basis of the dm1 mutation in the major histocompatibility complex of the mouse: a D/L hybrid geneQ36351221
Organization and evolution of D region class I genes in the mouse major histocompatibility complexQ36351824
A nonpolymorphic class I gene in the murine major histocompatibility complexQ36604416
The complete amino acid sequence of the murine transplantation antigen H-2Db as deduced by molecular cloningQ36648502
Microrecombinations generate sequence diversity in the murine major histocompatibility complex: analysis of the Kbm3, Kbm4, Kbm10, and Kbm11 mutantsQ36847160
Interaction between Kb and Q4 gene sequences generates the Kbm6 mutationQ36910005
Molecular studies of murine mutant BALB/c-H-2dm2 define a deletion of several class I genes including the entire H-2Ld geneQ37411901
Spontaneous H-2 mutants provide evidence that a copy mechanism analogous to gene conversion generates polymorphism in the major histocompatibility complexQ37600894
Evidence for an H-2/viral protein complex on the cell surface as the basis for the H-2 restriction of cytotoxicityQ39463923
H-2-linked murine cytotoxic T cell responses specific for sendai virus-infected cellsQ39523661
MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and ResponsivenessQ39576364
Complete sequence of constant and 3′ noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencingQ39638787
Murine major histocompatibility complex class-I mutants: molecular analysis and structure-function implicationsQ39733306
Genes of the Major Histocompatibility Complex in Mouse and ManQ40161786
Primary structural: analysis of the transplantation antigens of the murine H-2 major histocompatibility complexQ40312972
Lack of T-cell mediated cytotoxicity in M-MSV system depending on H-2 haplotypesQ40726324
Duplicated gene pairs and alleles of class I genes in the Qa2 region of the murine major histocompatibility complex: a comparisonQ41430047
A crucial role of the H-2 D locus in the regulation of both the D- and the K-associated cytotoxic T lymphocyte response against Moloney leukemia virus, demonstrated with two Db mutants.Q45794251
Inability of mice to generate cytotoxic T lymphocytes to vesicular stomatitis virus restricted to H-2Kk or H-2DkQ45802739
Primary structure of murine major histocompatibility complex alloantigens. Amino acid sequence of the NH2-terminal ninety-eight residues of the H-2Db glycoproteinQ54017460
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigensQ59092174
Evidence that multiple residues on both the alpha-helices of the class I MHC molecule are simultaneously recognized by the T cell receptorQ68094902
The H-2Kkml mutation: a single nucleotide substitution is responsible for multiple functional differences in a class I MHC moleculeQ68376134
Specificity and regulation of cytotoxic T-lymphocyte responses analyzed with H-2 mutantsQ70199611
Studies of twoH-2D b mutants: B6.C-H-2 bm13 and B6.C-H-2 bm14Q72620564
Allogeneic and associative recognition determinants of H-2 moleculesQ72729228
Mapping class I gene sequences in the major histocompatibility complexQ72933772
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectimmune responsivenessQ106892710
P304page(s)2319-2335
P577publication date1988-12-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleThree spontaneous H-2Db mutants are generated by genetic micro-recombination (gene conversion) events. Impact on the H-2-restricted immune responsiveness
P478volume168