Ethyl pyruvate protects against experimental acute-on-chronic liver failure in rats

scientific article

Ethyl pyruvate protects against experimental acute-on-chronic liver failure in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3748/WJG.V18.I40.5709
P932PMC publication ID3484339
P698PubMed publication ID23155311
P5875ResearchGate publication ID233424362

P50authorZuojiong GongQ61162460
P2093author name stringHui Chen
Cheng Fan
Xun Li
Lu-Wen Wang
Li-Kun Wang
Can-Ming He
P2860cites workHigh mobility group box-1 protein inhibits regulatory T cell immune activity in liver failure in patients with chronic hepatitis BQ64937350
Activation of gene expression in human neutrophils by high mobility group box 1 proteinQ73087842
Polyenylphosphatidylcholine prevents carbon tetrachloride-induced lipid peroxidation while it attenuates liver fibrosisQ73740629
Changes in intestinal microflora in patients with chronic severe hepatitisQ77458775
Systemic endotoxemia during chronic viral hepatitisQ78505626
Effects of lactitol on intestinal microflora and plasma endotoxin in patients with chronic viral hepatitisQ79269759
Increased serum and hepatic tissue levels of interleukin-18 in patients with fulminant hepatic failureQ80291576
The effect of ethyl pyruvate on oxidative stress in intestine and bacterial translocation after thermal injuryQ80490374
Not just nuclear proteins: 'novel' autophagy cancer treatment targets - p53 and HMGB1Q82746541
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
HMG-1 as a late mediator of endotoxin lethality in miceQ28139166
Targeting HMGB1 in inflammationQ28266138
RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophagesQ28568915
High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytesQ28574795
HMGB1: the jack-of-all-trades protein is a master DNA repair mechanicQ33799406
Novel HMGB1-inhibiting therapeutic agents for experimental sepsisQ33814903
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammationQ34156078
Reactive oxygen species as mediators of organ dysfunction caused by sepsis, acute respiratory distress syndrome, or hemorrhagic shock: potential benefits of resuscitation with Ringer's ethyl pyruvate solutionQ34530931
The pathophysiological basis of acute-on-chronic liver failureQ34830328
Intestinal endotoxemia as a pathogenetic mechanism in liver failureQ35002596
Ringer's ethyl pyruvate solution: a novel resuscitation fluid for the treatment of hemorrhagic shock and sepsisQ35136460
Cholinergic anti-inflammatory pathway activity and High Mobility Group Box-1 (HMGB1) serum levels in patients with rheumatoid arthritis.Q35856595
Acute liver failure: a critical appraisal of available animal modelsQ36355365
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusionQ36403403
Influence of heme oxygenase-1 expression on immune liver fibrosis induced by cobalt protoporphyrin in ratsQ37241948
Gabexate mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injuryQ39797512
HMGB1 develops enhanced proinflammatory activity by binding to cytokines.Q40016396
Pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin).Q40230859
Inflammation-promoting activity of HMGB1 on human microvascular endothelial cellsQ40686939
Ethyl pyruvate modulates acute inflammatory reactions in human endothelial cells in relation to the NF-kappaB pathwayQ40884597
Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model.Q42062324
A fulminant hepatic failure model in the rat: involvement of interleukin-1beta and tumor necrosis factor-alphaQ43709297
Resuscitation from hemorrhagic shock with Ringer's ethyl pyruvate solution improves survival and ameliorates intestinal mucosal hyperpermeability in ratsQ44031120
Role of the perforin/granzyme cell death pathway in D-Gal/LPS-induced inflammatory liver injuryQ44902660
Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemiaQ45020202
Ethyl pyruvate ameliorates liver ischemia-reperfusion injury by decreasing hepatic necrosis and apoptosisQ45235016
Ethyl pyruvate prevents intestinal inflammatory response and oxidative stress in a rat model of extrahepatic cholestasis.Q45921694
Effect of ethyl pyruvate on physical and immunological barriers of the small intestine in a rat model of sepsis.Q46017280
Ethyl pyruvate protects colonic anastomosis from ischemia-reperfusion injuryQ46209458
Ethyl pyruvate ameliorates liver injury secondary to severe acute pancreatitisQ46232195
PACAP inhibit the release and cytokine activity of HMGB1 and improve the survival during lethal endotoxemiaQ46421830
Post-synthetic acetylation of HMGB1 protein modulates its interactions with supercoiled DNA.Q46452162
Protective effects of ethyl pyruvate treatment on paraquat-intoxicated ratsQ46595796
Ethyl pyruvate ameliorates ileus induced by bowel manipulation in miceQ46743207
A critical role in structure-specific DNA binding for the acetylatable lysine residues in HMGB1.Q46778200
Establishment of a D-galactosamine/lipopolysaccharide induced acute-on-chronic liver failure model in ratsQ46929281
Effect of treatment with ethyl pyruvate on multiple organ dysfunction and mortality following delayed resuscitation after burn injury in ratQ46980846
Ethyl pyruvate improves survival and ameliorates distant organ injury in rats with severe acute pancreatitisQ46981742
P433issue40
P407language of work or nameEnglishQ1860
P921main subjectliver failureQ970208
P304page(s)5709-5718
P577publication date2012-10-01
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleEthyl pyruvate protects against experimental acute-on-chronic liver failure in rats
P478volume18

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cites work (P2860)
Q42266454Blockade of high-mobility group box-1 ameliorates acute on chronic liver failure in rats.
Q28068263Ethyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuries
Q41909868Ethyl pyruvate pretreatment attenuates concanavalin a-induced autoimmune hepatitis in mice.
Q42268031Ethyl pyruvate prevents inflammatory factors release and decreases intestinal permeability in rats with D-galactosamine-induced acute liver failure
Q36621514Improved prescription of taohechengqi-tang alleviates D-galactosamine acute liver failure in rats
Q39037784Inhibitions of NF-κB and TNF-α result in differential effects in rats with acute on chronic liver failure induced by d-Gal and LPS.
Q35843059Liuweiwuling tablets attenuate acetaminophen-induced acute liver injury and promote liver regeneration in mice
Q36815008Recombinant adenovirus containing hyper-interleukin-6 and hepatocyte growth factor ameliorates acute-on-chronic liver failure in rats
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Q41532442Trichostatin A Protects Against Experimental Acute-on-Chronic Liver Failure in Rats Through Regulating the Acetylation of Nuclear Factor-κB.