Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation

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Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation is …
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scholarly articleQ13442814

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P356DOI10.1016/J.PVR.2015.08.001
P932PMC publication ID4673669
P698PubMed publication ID26693182

P2093author name stringSung Hee Lee
No-Hee Park
Chang-Ryul Lee
Mo K Kang
Ki-Hyuk Shin
Reuben H Kim
Nicole Kristina Rigas
P2860cites workMiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2Q39420627
Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathwayQ39606694
miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-rasQ39618810
MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation.Q39786661
Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinomaQ39966384
Combined effects of human papillomavirus-18 and N-methyl-N'-nitro-N-nitrosoguanidine on the transformation of normal human oral keratinocytesQ41491044
Immortalization of normal human oral keratinocytes with type 16 human papillomavirusQ42806823
Human papillomavirus 16/18 E5 promotes cervical cancer cell proliferation, migration and invasion in vitro and accelerates tumor growth in vivoQ43456877
Human papillomavirus in oral exfoliated cells and risk of head and neck cancerQ44802936
Independent and combined effects of alcohol intake, tobacco smoking and betel quid chewing on the risk of esophageal cancer in TaiwanQ45083959
Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 yearsQ46214415
Unravelling cancer stem cell potentialQ53089167
HPV E6 induces eIF4E transcription to promote the proliferation and migration of cervical cancerQ53120123
Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cellsQ53226951
Strong association between infection with human papillomavirus and oral and oropharyngeal squamous cell carcinoma: a population-based case-control study in southern SwedenQ54630232
Inducible activation of oncogenic K-ras results in tumor formation in the oral cavityQ54707698
Southern blot hybridization and PCR in detection of oral human papillomavirus (HPV) infections in women with genital HPV infectionsQ67507779
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Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United StatesQ22306233
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44Q24617130
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcomeQ24657877
Origins and Mechanisms of miRNAs and siRNAsQ27860822
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cellsQ28246460
Squamous cell carcinoma of the tongue among young Indian adultsQ28360344
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAsQ29615910
Caught up in a Wnt storm: Wnt signaling in cancerQ29617494
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cellsQ29619847
Alteration of microRNA profiles in squamous cell carcinoma of the head and neck cell lines by human papillomavirusQ34127590
The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancerQ34219266
The hedgehog signaling pathway in cancerQ34576345
The microRNA miR-34a inhibits non-small cell lung cancer (NSCLC) growth and the CD44hi stem-like NSCLC cellsQ35111253
Viral infections in oral mucosa.Q35970119
Recent insights into the role of Notch signaling in tumorigenesisQ36314431
High risk HPV types 18 and 16 are potent modulators of oral squamous cell carcinoma phenotypes in vitroQ36391611
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.Q36741216
Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells.Q36748177
Gene discovery in cervical cancer : towards diagnostic and therapeutic biomarkersQ36982644
Diagnostic utility of p16INK4a: a reappraisal of its use in cervical biopsiesQ37150943
MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.Q37156452
Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotypeQ37184447
Human papillomavirus in head and neck cancer: its role in pathogenesis and clinical implicationsQ37622609
Genetic and molecular alterations associated with oral squamous cell cancer (Review).Q37626579
Elevated intrinsic cancer stem cell population in human papillomavirus-associated head and neck squamous cell carcinomaQ37652879
Clinical, pathological and molecular determinants in squamous cell carcinoma of the oral cavityQ37750805
MicroRNAs in the p53 network: micromanagement of tumour suppressionQ38035144
MicroRNAs involved in regulating epithelial-mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics.Q38043263
HPV16 E5 expression induces switching from FGFR2b to FGFR2c and epithelial-mesenchymal transitionQ38934698
A novel function of HPV16-E6/E7 in epithelial–mesenchymal transitionQ39158629
MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD geneQ39305395
TNFα enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cellsQ39326301
P921main subjecthuman papillomavirus 16Q69461345
human papilloma virusQ69999790
P304page(s)116-125
P577publication date2015-12-01
P1433published inPapillomavirus research (Amsterdam, Netherlands)Q27726667
P1476titleHuman papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation
P478volume1

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Q26767061The Role of HPV in Head and Neck Cancer Stem Cell Formation and Tumorigenesis
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