Zebrafish models flex their muscles to shed light on muscular dystrophies

scientific article

Zebrafish models flex their muscles to shed light on muscular dystrophies is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1242/DMM.010082
P932PMC publication ID3484855
P698PubMed publication ID23115202
P5875ResearchGate publication ID232745858

P50authorPeter D. CurrieQ56046863
Joachim BergerQ57431900
P2860cites workSkeletal muscle laminin and MDC1A: pathogenesis and treatment strategiesQ22001192
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophyQ24306218
Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophyQ24308817
Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycanQ24316123
Mutations in the integrin alpha7 gene cause congenital myopathyQ24317420
Type VI collagen mutations in Bethlem myopathy, an autosomal dominant myopathy with contracturesQ24318933
Ullrich scleroatonic muscular dystrophy is caused by recessive mutations in collagen type VIQ24629650
Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept studyQ24643018
The zebrafish candyfloss mutant implicates extracellular matrix adhesion failure in laminin alpha2-deficient congenital muscular dystrophyQ24681141
Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124Q27660081
Chimaeric mice deficient in dystroglycans develop muscular dystrophy and have disrupted myoneural synapsesQ28141198
Defective membrane repair in dysferlin-deficient muscular dystrophyQ28203095
In vivo imaging of molecular interactions at damaged sarcolemmaQ28261975
Dysferlin, a novel skeletal muscle gene, is mutated in Miyoshi myopathy and limb girdle muscular dystrophyQ28281738
A gene related to Caenorhabditis elegans spermatogenesis factor fer-1 is mutated in limb-girdle muscular dystrophy type 2BQ28281749
Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null miceQ28590908
The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesisQ28754755
Animal models of human disease: zebrafish swim into viewQ29615723
Dystrophin: the protein product of the Duchenne muscular dystrophy locusQ29618077
The zebrafish dystrophic mutant softy maintains muscle fibre viability despite basement membrane rupture and muscle detachmentQ30490034
The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathiesQ30499359
The dystrophin associated protein complex in zebrafishQ31134324
Zebrafish orthologs of human muscular dystrophy genesQ33279472
The role of zebrafish in chemical geneticsQ33300427
Zebrafish models for human FKRP muscular dystrophiesQ33594227
Drug screening in a zebrafish model of Duchenne muscular dystrophy.Q33845739
Zebrafish models of collagen VI-related myopathiesQ33878282
PTC124 targets genetic disorders caused by nonsense mutationsQ34003720
Very mild muscular dystrophy associated with the deletion of 46% of dystrophinQ34371637
Dystrophin in adult zebrafish muscleQ74393273
Local dystrophin restoration with antisense oligonucleotide PRO051Q80412961
The 2012 version of the gene table of monogenic neuromuscular disordersQ83257090
The struggle to model muscular dystrophyQ84327051
Zebrafish Fukutin family proteins link the unfolded protein response with dystroglycanopathiesQ34766986
A dystroglycan mutation associated with limb-girdle muscular dystrophy.Q34767085
Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complexQ34774115
Current status of pharmaceutical and genetic therapeutic approaches to treat DMD.Q34994545
Interventions for muscular dystrophy: molecular medicines entering the clinicQ35014916
Evaluation of exon-skipping strategies for Duchenne muscular dystrophy utilizing dystrophin-deficient zebrafishQ35216325
A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.Q36232550
Forced expression of dystrophin deletion constructs reveals structure-function correlations.Q36237129
Mutations in LAMB2 causing a severe form of synaptic congenital myasthenic syndromeQ37098005
Genetic isolation and characterization of a splicing mutant of zebrafish dystrophinQ37102146
Dystroglycanopathies: coming into focusQ37852376
Exercise and Duchenne muscular dystrophy: toward evidence-based exercise prescription.Q37853099
Targeting RNA to treat neuromuscular diseaseQ37909000
Developmental defects in a zebrafish model for muscular dystrophies associated with the loss of fukutin-related protein (FKRP).Q38291016
Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cellsQ38299785
Different localization of dystrophin in developing and adult human skeletal muscleQ41985725
Characterization of zebrafish dysferlin by morpholino knockdown.Q42255405
Targeted gene disruption in somatic zebrafish cells using engineered TALENsQ42862072
Protein O-mannosylation is necessary for normal embryonic development in zebrafishQ43064260
Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency.Q44661085
Expression of Deletion-Containing Dystrophins in mdx Muscle: Implications for Gene Therapy and Dystrophin FunctionQ45868162
Kindlin-2 is an essential component of intercalated discs and is required for vertebrate cardiac structure and function.Q46823860
Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryoQ47073103
Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos.Q47073130
Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva.Q47073234
The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesisQ47073713
Dystrophin-deficient zebrafish feature aspects of the Duchenne muscular dystrophy pathologyQ47073756
The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafishQ47073763
Delta-sarcoglycan is necessary for early heart and muscle development in zebrafishQ47073817
Quantification of birefringence readily measures the level of muscle damage in zebrafish.Q47073970
Delta-sarcoglycan is required for early zebrafish muscle organizationQ47074188
Conserved synteny and the zebrafish genomeQ48055824
Collagen VI deficiency induces early onset myopathy in the mouse: an animal model for Bethlem myopathy.Q52532612
Characterisation of dystrophin during development of human skeletal muscleQ68134305
P433issue6
P921main subjecteukaryoteQ19088
tissueQ40397
Danio rerioQ169444
human musculoskeletal systemQ726543
animal disease modelQ64732998
biomedical investigative techniqueQ66648976
P304page(s)726-732
P577publication date2012-11-01
P1433published inDisease Models & MechanismsQ1524006
P1476titleZebrafish models flex their muscles to shed light on muscular dystrophies
P478volume5

Reverse relations

cites work (P2860)
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Q36305781Computational approaches for understanding the diagnosis and treatment of Parkinson's disease
Q37610505Current Translational Research and Murine Models For Duchenne Muscular Dystrophy.
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Q89448668Duchenne muscular dystrophy animal models for high-throughput drug discovery and precision medicine
Q54221386Endotoxin molecule lipopolysaccharide-induced zebrafish inflammation model: a novel screening method for anti-inflammatory drugs.
Q38785603Establishment and Characterization of a New Muscle Cell Line of Zebrafish (Danio rerio) as an In Vitro Model for Gene Expression Studies
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Q90147730Failure to identify modifiers of NEBULIN-related nemaline myopathy in two pre-clinical models of the disease
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Q56814708Model organism data evolving in support of translational medicine
Q26991681Model organisms in the fight against muscular dystrophy: lessons from drosophila and Zebrafish
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Q37529679Skeletal muscle fiber type: using insights from muscle developmental biology to dissect targets for susceptibility and resistance to muscle disease
Q27028125Swimming into prominence: the zebrafish as a valuable tool for studying human myopathies and muscular dystrophies.
Q35228265Swimming-induced exercise promotes hypertrophy and vascularization of fast skeletal muscle fibres and activation of myogenic and angiogenic transcriptional programs in adult zebrafish
Q40975689Tmem2 regulates cell-matrix interactions that are essential for muscle fiber attachment
Q49642318Zebrafish Embryonic Slow Muscle Is a Rapid System for Genetic Analysis of Sarcomere Organization by CRISPR/Cas9, but Not NgAgo
Q34389847Zebrafish as a model system to study toxicology
Q53477530[Potential of the zebrafish model to study congenital muscular dystrophies].

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