Kaposi's Sarcoma-Associated Herpesvirus Interleukin-6 Modulates Endothelial Cell Movement by Upregulating Cellular Genes Involved in Migration

scientific article

Kaposi's Sarcoma-Associated Herpesvirus Interleukin-6 Modulates Endothelial Cell Movement by Upregulating Cellular Genes Involved in Migration is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MBIO.01499-15
P932PMC publication ID4676281
P698PubMed publication ID26646010

P50authorBlossom DamaniaQ27921691
Louise GiffinQ74933010
P2093author name stringJohn A West
P2860cites workNIH Image to ImageJ: 25 years of image analysisQ23319322
Transmembrane CEACAM1 affects integrin-dependent signaling and regulates extracellular matrix protein-specific morphology and migration of endothelial cellsQ24293449
Biliary glycoprotein, a potential human cell adhesion molecule, is down-regulated in colorectal carcinomasQ24564315
KSHV: pathways to tumorigenesis and persistent infectionQ27026000
CEA-related cell adhesion molecule 1: a potent angiogenic factor and a major effector of vascular endothelial growth factorQ28199550
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcomaQ28242984
Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) miceQ28266642
The global health burden of infection-associated cancers in the year 2002Q28290871
Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomasQ28299069
Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-SrcQ28508235
Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivoQ28588612
Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's diseaseQ29619158
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activityQ33282964
Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1Q33484744
Kinetics of Kaposi's sarcoma-associated herpesvirus gene expressionQ33653424
Human herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6.Q33819690
Kaposi sarcoma-associated herpesvirus infects monotypic (IgM lambda) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders.Q33939333
Detection of viral interleukin-6 in Kaposi sarcoma-associated herpesvirus-linked disordersQ33939338
Acquired immunodeficiency syndrome-associated cancers in Sub-Saharan AfricaQ34218212
Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV.Q34408877
Human cytomegalovirus-encoded pUL7 is a novel CEACAM1-like molecule responsible for promotion of angiogenesisQ34440895
HIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β signaling pathwayQ34542341
Colocalization of the viral interleukin-6 with latent nuclear antigen-1 of human herpesvirus-8 in endothelial spindle cells of Kaposi's sarcoma and lymphoid cells of multicentric Castleman's diseaseQ73427381
Serum viral interleukin-6 in AIDS-related multicentric Castleman diseaseQ73768899
CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic diseaseQ74099040
Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirusQ77136406
The expression of CD66a and possible roles in colorectal adenoma and adenocarcinomaQ79401885
CEACAM1, a novel serum biomarker for pancreatic cancerQ80188196
Pro-angiogenic signaling by the endothelial presence of CEACAM1Q80984514
On the role of CEACAM1 in cancerQ81232134
Systemic dysregulation of CEACAM1 in melanoma patientsQ84295467
Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivatorQ34782463
Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphomaQ35131811
Kaposi's sarcoma-associated herpesvirus infection of blood endothelial cells induces lymphatic differentiationQ35137826
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody productionQ35138138
CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cellsQ35627666
Human herpesvirus 8 viral interleukin-6 interacts with splice variant 2 of vitamin K epoxide reductase complex subunit 1.Q35689626
Expression of a virus-derived cytokine, KSHV vIL-6, in HIV-seronegative Castleman's diseaseQ35764989
Human herpesvirus 8 encodes a homolog of interleukin-6.Q35876140
HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in miceQ36018434
Concurrent expression of latent and a limited number of lytic genes with immune modulation and antiapoptotic function by Kaposi's sarcoma-associated herpesvirus early during infection of primary endothelial and fibroblast cells and subsequent declinQ37010247
Determinants of secretion and intracellular localization of human herpesvirus 8 interleukin-6.Q37232908
Complex N-linked glycans on Asn-89 of Kaposi sarcoma herpes virus-encoded interleukin-6 mediate optimal function by affecting cytokine protein conformationQ37447587
The expression and modulation of CEACAM1 and tumor cell transformationQ38023157
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasisQ38125604
KSHV-encoded viral IL-6 activates multiple human IL-6 signaling pathwaysQ38318315
The CEACAM1-L glycoprotein associates with the actin cytoskeleton and localizes to cell-cell contact through activation of Rho-like GTPasesQ38477338
Upregulation of the TLR3 pathway by Kaposi's sarcoma-associated herpesvirus during primary infectionQ38610318
Modulation of Kaposi's sarcoma-associated herpesvirus interleukin-6 function by hypoxia-upregulated protein 1.Q38985652
Signal transduction by human herpesvirus 8 viral interleukin-6 (vIL-6) is modulated by the nonsignaling gp80 subunit of the IL-6 receptor complex and is distinct from signaling induced by human IL-6.Q39290036
Re-expression of CEACAM1 long cytoplasmic domain isoform is associated with invasion and migration of colorectal cancerQ39574908
Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposi's sarcoma-associated herpesvirusQ39729318
The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virionsQ39877021
Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cellsQ39877852
CEACAM1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases.Q40216819
Dual role of carcinoembryonic antigen-related cell adhesion molecule 1 in angiogenesis and invasion of human urinary bladder cancer.Q40479962
Kaposi's sarcoma-associated herpesvirus-encoded viral interleukin-6 is secreted and modified differently than human interleukin-6: evidence for a unique autocrine signaling mechanismQ40534487
Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expressionQ40537413
Human herpesvirus 8-encoded interleukin-6 homologue (viral IL-6) induces endogenous human IL-6 secretionQ40872607
Characterization of signaling cascades triggered by human interleukin-6 versus Kaposi's sarcoma-associated herpes virus-encoded viral interleukin 6.Q40890381
A Kaposi's sarcoma-associated herpesvirus-encoded cytokine homolog (vIL-6) activates signaling through the shared gp130 receptor subunitQ41098043
Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6.Q41125455
Human herpesvirus 8 interleukin-6 contributes to primary effusion lymphoma cell viability via suppression of proapoptotic cathepsin D, a cointeraction partner of vitamin K epoxide reductase complex subunit 1 variant 2.Q41909015
Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cellsQ42141115
cis-Determinants in the cytoplasmic domain of CEACAM1 responsible for its tumor inhibitory functionQ42809766
Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6.Q42814766
Carcinoembryonic antigen cell adhesion molecule 1 directly associates with cytoskeleton proteins actin and tropomyosinQ43763073
High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric castleman disease in HIV-infected patients.Q44424254
Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus.Q45769785
CEACAM1: a novel urinary marker for bladder cancer detectionQ47678360
Protein expression of carcinoembryonic antigen cell adhesion molecules in benign and malignant melanocytic skin lesionsQ47747746
The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factorsQ47755368
To the editor: Murine gammaherpesvirus 68 (MHV-68) escapes from NK-cell-mediated immune surveillance by a CEACAM1-mediated immune evasion mechanism.Q51841441
CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation.Q53287381
Optimal ratios of biliary glycoprotein isoforms required for inhibition of colonic tumor cell growth.Q53442183
Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cellsQ71563744
P4510describes a project that usesImageJQ1659584
P433issue6
P921main subjectendotheliumQ111140
cell migrationQ189092
P304page(s)e01499-15
P577publication date2015-12-08
P1433published inmBioQ15817061
P1476titleKaposi's Sarcoma-Associated Herpesvirus Interleukin-6 Modulates Endothelial Cell Movement by Upregulating Cellular Genes Involved in Migration
P478volume6

Reverse relations

cites work (P2860)
Q26741576A Central Role for STAT3 in Gammaherpesvirus-Life Cycle and -Diseases
Q89868075Epstein-Barr Virus and Human Herpesvirus 8 in Idiopathic Pulmonary Fibrosis
Q90379391Human Cytomegalovirus Upregulates Expression of HCLS1 Resulting in Increased Cell Motility and Transendothelial Migration during Latency
Q41919772Kaposi's Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes
Q60949741Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral IL-6 (vIL-6) Enhances Immunoglobulin Class-Switch Recombination
Q92185487Kinome profiling of non-Hodgkin lymphoma identifies Tyro3 as a therapeutic target in primary effusion lymphoma
Q92238951Modulation of Angiogenic Processes by the Human Gammaherpesviruses, Epstein-Barr Virus and Kaposi's Sarcoma-Associated Herpesvirus
Q39173806Modulation of oncogenic signaling networks by Kaposi's sarcoma-associated herpesvirus
Q93211764Similar Immunological Profiles Between African Endemic and Human Immunodeficiency Virus Type 1-Associated Epidemic Kaposi Sarcoma (KS) Patients Reveal the Primary Role of KS-Associated Herpesvirus in KS Pathogenesis
Q91168794Suppression of the SAP18/HDAC1 complex by targeting TRIM56 and Nanog is essential for oncogenic viral FLICE-inhibitory protein-induced acetylation of p65/RelA, NF-κB activation, and promotion of cell invasion and angiogenesis
Q59126441The Kaposi's sarcoma-associated herpesvirus viral interleukin 6 gene affects metastasis and expression of B cell markers in a murine xenograft model
Q94562806Viral interleukin-6 encoded by an oncogenic virus promotes angiogenesis and cellular transformation by enhancing STAT3-mediated epigenetic silencing of caveolin 1
Q96586662p300 Promotes Cell Proliferation through Suppressing Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Reactivation in the Infected B-Lymphoma Cells

Search more.