FOXO1 Up-Regulates Human L-selectin Expression Through Binding to a Consensus FOXO1 Motif

scientific article

FOXO1 Up-Regulates Human L-selectin Expression Through Binding to a Consensus FOXO1 Motif is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4137/GRSB.S10343
P932PMC publication ID3486891
P698PubMed publication ID23133314

P2093author name stringXitong Dang
Xiaojiong Lu
Yuefen Lou
P2860cites workT cells require Foxo1 to populate the peripheral lymphoid organsQ41486256
L-selectin can mediate leukocyte rolling in untreated mesenteric venules in vivo independent of E- or P-selectinQ41532547
ADAM-17-independent shedding of L-selectinQ42446882
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequenceQ42472986
ADAM17 but not ADAM10 mediates tumor necrosis factor-alpha and L-selectin shedding from leukocyte membranesQ43595800
Role of selectins in experimental Staphylococcus aureus-induced arthritisQ44059601
T lymphocyte rolling and recruitment into peripheral lymph nodes is regulated by a saturable density of L-selectin (CD62L).Q44928569
T lymphocyte activation initiates the degradation of the CD62L encoding mRNA and increases the transcription of the corresponding geneQ44964180
Inhibition of coronary thrombosis and local inflammation by a noncarbohydrate selectin inhibitorQ45872581
Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient miceQ46148261
FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinaseQ46421523
Role of the forkhead transcription family member, FKHR, in thymocyte differentiation.Q52163167
Selectin synthesis and inflammationQ71641184
L-selectin gene T668C mutation in type 1 diabetes patients and their first degree relativesQ73154496
Soluble L-selectin levels in type I diabetes mellitus: a surrogate marker for disease activity?Q73486536
Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcriptionQ73509889
Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitorsQ74177531
L-selectin gene polymorphisms in Graves' diseaseQ80232028
Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcriptionQ80427894
Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophilsQ24300431
Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradationQ24673179
Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the visceraQ28513113
Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activityQ28573827
Relevance of L-selectin shedding for leukocyte rolling in vivoQ30303640
L-selectin shedding regulates leukocyte recruitmentQ30307158
Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expressionQ30454354
Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetateQ31825884
Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.Q33797113
Insulin-regulated gene expressionQ34332489
Highly specialized role of Forkhead box O transcription factors in the immune system.Q34492548
FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity.Q34521158
Phosphoinositide 3-kinases in immunity: lessons from knockout miceQ34583734
Foxo: in command of T lymphocyte homeostasis and toleranceQ34645402
Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHRQ34666304
L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesisQ35049150
Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off dutyQ35139549
FOXO transcription factors as regulators of immune homeostasis: molecules to die for?Q35193785
L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes.Q36371875
Interferon-alpha induces the expression of the L-selectin homing receptor in human B lymphoid cellsQ36534778
Selectins and glycosyltransferases in leukocyte rolling in vivoQ36586954
Transcriptional regulation of mouse L-selectinQ37116497
ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alphaQ37127274
FoxO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrolQ37431323
Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteinsQ37535142
The cytoplasmic domains of TNFalpha-converting enzyme (TACE/ADAM17) and L-selectin are regulated differently by p38 MAPK and PKC to promote ectodomain sheddingQ39724302
Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditureQ40030179
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasisQ40265984
Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.Q40301333
Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.Q40849405
Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cellsQ40854166
A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transductionQ40866321
Constitutive overexpression of the L-selectin gene in fresh leukemic cells of adult T-cell leukemia that can be transactivated by human T-cell lymphotropic virus type 1 Tax.Q41282256
P304page(s)139-149
P577publication date2012-10-29
P1433published inGene Regulation and Systems BiologyQ15753741
P1476titleFOXO1 Up-Regulates Human L-selectin Expression Through Binding to a Consensus FOXO1 Motif
P478volume6

Reverse relations

cites work (P2860)
Q92074475Eosinophilic Esophagitis in Esophageal Atresia
Q48188402Lack of Ikaros cripples expression of Foxo1 and its targets in naive T cells.

Search more.