Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague-Dawley rats

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Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague-Dawley rats is …
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P6179Dimensions Publication ID1018156768
P356DOI10.1186/S13293-015-0049-3
P932PMC publication ID4676821
P698PubMed publication ID26693004
P5875ResearchGate publication ID286636696

P50authorStaci BilboQ90106017
Jaclyn M SchwarzQ90426650
P2093author name stringCaitlin K Posillico
Laurne S Terasaki
P2860cites workThe "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting gliaQ24650739
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesiaQ24650758
Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)Q28288846
Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activationQ28564261
Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesiaQ28568886
Microglia and memory: modulation by early-life infectionQ30468271
Sex differences in micro-opioid receptor expression in the rat midbrain periaqueductal gray are essential for eliciting sex differences in morphine analgesiaQ33642749
Sexually dimorphic activation of the periaqueductal gray-rostral ventromedial medullary circuit during the development of tolerance to morphine in the rat.Q33650162
Sex differences in the anatomical and functional organization of the periaqueductal gray-rostral ventromedial medullary pathway in the rat: a potential circuit mediating the sexually dimorphic actions of morphineQ33661832
Sex differences in minocycline-induced neuroprotection after experimental strokeQ33794484
Persistent pain model reveals sex difference in morphine potencyQ33797829
Opioid activation of toll-like receptor 4 contributes to drug reinforcementQ34294203
Sex differences in opioid analgesia: "from mouse to man".Q34534284
CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease.Q34576624
Sex differences in drug- and non-drug-induced analgesiaQ35101105
Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female miceQ35556560
Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicityQ35611320
Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expressionQ35676825
Sex-independent neuroprotection with minocycline after experimental thromboembolic strokeQ35779826
Spinal synthesis of estrogen and concomitant signaling by membrane estrogen receptors regulate spinal κ- and μ-opioid receptor heterodimerization and female-specific spinal morphine antinociceptionQ35877147
Morphine activates neuroinflammation in a manner parallel to endotoxinQ35924760
The chemokine CX3CL1/fractalkine interferes with the antinociceptive effect induced by opioid agonists in the periaqueductal grey of ratsQ35966430
Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in ratsQ36157812
Different immune cells mediate mechanical pain hypersensitivity in male and female mice.Q36633603
Methamphetamine causes microglial activation in the brains of human abusers.Q36801473
The role of MAC1 in diesel exhaust particle-induced microglial activation and loss of dopaminergic neuron functionQ36863858
A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4.Q36917936
Maternal stress and effects of prenatal air pollution on offspring mental health outcomes in mice.Q37149782
Glia in pathological pain: a role for fractalkineQ37189198
Blockade of Toll-like receptor 4 attenuates morphine tolerance and facilitates the pain relieving properties of morphineQ37208498
Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesiaQ37438487
Spinal endomorphin 2 antinociception and the mechanisms that produce it are both sex- and stage of estrus cycle-dependent in rats.Q37693807
Persistent peripheral inflammation attenuates morphine-induced periaqueductal gray glial cell activation and analgesic tolerance in the male rat.Q37710121
Fractalkine/CX3CR1 signaling during neuropathic painQ38213379
Minocycline selectively inhibits M1 polarization of microgliaQ39496127
Organismic variables and pain inhibition: roles of gender and agingQ39560248
Ventromedial and medial preoptic hypothalamic ibotenic acid lesions potentiate systemic morphine analgesia in female, but not male ratsQ42949094
Importance of sex and relative efficacy at the mu opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioidsQ43794888
Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathyQ44268069
Relationship of spinal dynorphin neurons to delta-opioid receptors and estrogen receptor alpha: anatomical basis for ovarian sex steroid opioid antinociception.Q44328892
Sex, pain, and opioids: interdependent influences of sex and pain modality on dynorphin-mediated antinociception in ratsQ44681220
Minocycline inhibits neuronal death and glial activation induced by beta-amyloid peptide in rat hippocampusQ45028409
Microglial activation is a pharmacologically specific marker for the neurotoxic amphetaminesQ45036507
Differential modulation of TMJ neurons in superficial laminae of trigeminal subnucleus caudalis/upper cervical cord junction region of male and cycling female rats by morphine.Q45284281
Reversal of sex differences in morphine analgesia elicited from the ventrolateral periaqueductal gray in rats by neonatal hormone manipulationsQ45711407
Minocycline or iNOS inhibition block 3-nitrotyrosine increases and blood-brain barrier leakiness in amyloid beta-peptide-injected rat hippocampusQ46946375
Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in ratsQ48271488
Sex-related differences in morphine's antinociceptive activity: relationship to serum and brain morphine concentrationsQ48649920
Sex differences in development of morphine tolerance and dependence in the rat.Q52534906
Roles of gender, gonadectomy and estrous phase in the analgesic effects of intracerebroventricular morphine in ratsQ69449855
Sex-related differences in the effects of morphine and stress on visceral painQ69793149
Analysis of sex and gonadectomy differences in beta-endorphin antinociception elicited from the ventrolateral periaqueductal gray in ratsQ73670714
Antinociceptive and behavioral activation responses elicited by d-Pro(2)-endomorphin-2 in the ventrolateral periaqueductal gray are sensitive to sex and gonadectomy differences in ratsQ73943270
P921main subjectminocyclineQ415336
P304page(s)33
P577publication date2015-12-12
P1433published inBiology of Sex DifferencesQ27723474
P1476titleExamination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague-Dawley rats
P478volume6