Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells.

scientific article

Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3324/HAEMATOL.2011.061408
P932PMC publication ID3487441
P698PubMed publication ID22689689
P5875ResearchGate publication ID225293497

P50authorCéline PangaultQ59609247
Michel CognéQ30118126
P2093author name stringKarin Tarte
Marjolein van Egmond
Daniel Drocourt
Gérard Tiraby
Armelle Cuvillier
Brice Laffleur
Virginie Pascal
Arnaud Debin
Laurent Imbertie
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Interaction of immunoglobulin A with complement and phagocytic cellsQ69389397
Fc alpha receptors mediate release of tumour necrosis factor-alpha and interleukin-6 by human monocytes following receptor aggregationQ71819211
C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisitedQ73326011
Signaling events involved in anti-CD20-induced apoptosis of malignant human B cellsQ73638542
Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8aQ73968562
Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodiesQ74213454
Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa geneQ77535970
Complement activation plays a key role in the side-effects of rituximab treatmentQ77637131
Human immunoglobulin A receptor (FcalphaRI, CD89) function in transgenic mice requires both FcR gamma chain and CR3 (CD11b/CD18)Q77850461
Monomeric and polymeric IgA show a similar association with the myeloid FcalphaRI/CD89Q83288035
Superagonistic CD28 stimulation of allogeneic T cells protects from acute graft-versus-host diseaseQ84500241
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HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysisQ33479955
Expression of homing receptors on IgA1 and IgA2 plasmablasts in blood reflects differential distribution of IgA1 and IgA2 in various body fluidsQ33725110
A novel human IgA monoclonal antibody protects against tuberculosisQ33800841
Multiple roles for the major histocompatibility complex class I- related receptor FcRnQ33932754
The intriguing role of polymorphonuclear neutrophils in antitumor reactions.Q34128787
Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotypeQ34434169
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The function of immunoglobulin A in immunityQ36346119
Depletion of the C3 component of complement enhances the ability of rituximab-coated target cells to activate human NK cells and improves the efficacy of monoclonal antibody therapy in an in vivo modelQ37484505
TRAIL and other TRAIL receptor agonists as novel cancer therapeuticsQ37598582
Recombinant dimeric IgA antibodies against the epidermal growth factor receptor mediate effective tumor cell killing.Q39593092
Impact of human IgA antibodies on complement-dependent cytotoxicity mediated by combinations of EGF-R-directed antibodiesQ39699202
Development of an in vivo antibody-mediated killing (IVAK) model, a flow cytometric method to rapidly evaluate therapeutic antibodiesQ40006850
Immature neutrophils mediate tumor cell killing via IgA but not IgG Fc receptorsQ40432649
Transepithelial transport of immunoglobulinsQ40661174
Chimeric IgA antibodies against HLA class II effectively trigger lymphoma cell killingQ40694990
Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid raftsQ40695150
Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.Q42940097
FcalphaRI (CD89) as a novel trigger molecule for bispecific antibody therapyQ43447889
Human IgA activates the complement system via the mannan-binding lectin pathwayQ43710180
Glucocorticoids and rituximab in vitro: synergistic direct antiproliferative and apoptotic effects.Q44102003
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.Q45861628
In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling.Q46131685
Human IgA1 initiates complement-mediated killing of Neisseria meningitidisQ46912472
Complement activation determines the therapeutic activity of rituximab in vivo.Q47745204
Effector mechanisms of recombinant IgA antibodies against epidermal growth factor receptor.Q53533176
Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin.Q54018517
Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis.Q54048451
P433issue11
P304page(s)1686-1694
P577publication date2012-06-11
P1433published inHaematologicaQ5638209
P1476titleAnti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells
P478volume97

Reverse relations

cites work (P2860)
Q48223734Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity.
Q33891585Exploring Site-Specific N-Glycosylation of HEK293 and Plant-Produced Human IgA Isotypes
Q38239286Fc receptor-dependent mechanisms of monoclonal antibody therapy of cancer
Q41704272Human Cell Line-Derived Monoclonal IgA Antibodies for Cancer Immunotherapy
Q64060912IgA and FcαRI: Pathological Roles and Therapeutic Opportunities
Q91811769IgA: Structure, Function, and Developability
Q37138332Improved in vivo anti-tumor effects of IgA-Her2 antibodies through half-life extension and serum exposure enhancement by FcRn targeting
Q46027197Myeloid cells as effector cells for monoclonal antibody therapy of cancer.
Q97643316Neutrophil diversity and plasticity in tumour progression and therapy
Q41061029Neutrophils trigger a NF-κB dependent polarization of tumor-supportive stromal cells in germinal center B-cell lymphomas.
Q92248471Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice
Q42372842Therapeutic Antibodies: What Have We Learnt from Targeting CD20 and Where Are We Going?

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