Expression of human estrogen receptor-alpha and -beta, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells

scientific article

Expression of human estrogen receptor-alpha and -beta, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1999PNAS...96.5722L
P356DOI10.1073/PNAS.96.10.5722
P932PMC publication ID21927
P698PubMed publication ID10318951
P5875ResearchGate publication ID12979609

P50authorKin-Mang LauQ58469938
P2093author name stringS C Mok
S M Ho
P2860cites workER beta: identification and characterization of a novel human estrogen receptorQ24317610
Cloning of a novel receptor expressed in rat prostate and ovaryQ24607949
Expression of estrogen receptor beta messenger RNA variant in breast cancerQ28259978
Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: down-regulation of ER-beta in neoplastic tissuesQ28264982
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and betaQ28304508
Responses in the brain of estrogen receptor alpha-disrupted miceQ36604561
Endocrine Factors in Common Epithelial Ovarian Cancer*Q37176622
Does HRT modify risk of gynecological cancers?Q39479229
Refinement of two chromosome 11q regions of loss of heterozygosity in ovarian cancer.Q40949679
SKOV3 ovarian carcinoma cells have functional estrogen receptor but are growth-resistant to estrogen and antiestrogensQ41265574
Estrogen action in human ovarian cancerQ41457706
Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor actionQ41546396
Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrixQ41606674
Cloning of the rat progesterone receptor gene 5'-region and identification of two functionally distinct promotersQ42804329
Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs).Q42805879
Human chorionic gonadotropin, follicle-stimulating hormone, and luteinizing hormone in patients with epithelial ovarian carcinomaQ44026933
Transcriptional control of estrogen receptor in estrogen receptor-negative breast carcinoma.Q46193488
Exploring the role of sex steroids through studies of receptor deficient miceQ47861980
Estrogen receptor beta: re-evaluation of estrogen and antiestrogen signalingQ47997907
Estrogen receptor mutations in tamoxifen-resistant breast cancerQ48085724
Plasma level of estradiol in patients with ovarian malignant tumors.Q51770095
Testosterone, SHBG and albumin in patients with ovarian carcinoma.Q51815599
Estrogen receptor-beta mRNA expression in rat ovary: down-regulation by gonadotropins.Q52196619
Definition and refinement of a region of loss of heterozygosity at 11q23.3-q24.3 in epithelial ovarian cancer associated with poor prognosis.Q52519614
Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogenQ67446195
Extension of the life-span of human endothelial cells by an interleukin-1 alpha antisense oligomerQ68568858
Ovarian and peripheral androgen and oestrogen levels in post-menopausal women: correlations with ovarian histologyQ69497452
Elevated progesterone levels in serum and ovarian venous blood in patients with ovarian tumorsQ69791021
Gonadal steroids, gonadotropins and endometrial histology in postmenopausal women with malignant ovarian tumorsQ70301050
Ovarian and peripheral plasma levels of progestogens, androgens and oestrogens in post-menopausal womenQ70596141
Relationship between aromatase activity and steroid receptor levels in ovarian tumors from postmenopausal womenQ70667848
Mutations of the estrogen receptor in endometrial carcinoma: evidence of an association with high tumor gradeQ71763510
Estrogen replacement therapy and fatal ovarian cancerQ72157255
Aging and development of ovarian epithelial carcinoma: the relevance of changes in ovarian stromal androgen productionQ72917090
An estrogen receptor mutant with strong hormone-independent activity from a metastatic breast cancerQ73221160
Progesterone induces apoptosis and up-regulation of p53 expression in human ovarian carcinoma cell linesQ73335132
Rat estrogen receptor-alpha and -beta, and progesterone receptor mRNA expression in various prostatic lobes and microdissected normal and dysplastic epithelial tissues of the Noble ratsQ74013327
A one centimorgan deletion unit on chromosome Xq12 is commonly lost in borderline and invasive epithelial ovarian tumorsQ74178345
Cancer incidence in a cohort of infertile womenQ74628783
Hormone replacement therapy and the risk of epithelial ovarian carcinoma: a meta-analysisQ77168041
Expression of oestrogen receptor alpha and beta in cultured human ovarian surface epithelial cellsQ77227947
Identification of a variant estrogen receptor lacking exon 4 and its coexpression with wild-type estrogen receptor in ovarian carcinomasQ77556510
Hormonal etiology of epithelial ovarian cancer, with a hypothesis concerning the role of androgens and progesteroneQ77636062
Differential expression of estrogen receptor-alpha and -beta messenger RNAs as a potential marker of ovarian carcinogenesisQ77670035
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectestrogenQ277954
P1104number of pages6
P304page(s)5722-5727
P577publication date1999-05-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleExpression of human estrogen receptor-alpha and -beta, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells
P478volume96

Reverse relations

described by source (P1343)
Q54808585Caov-3
Q54831365DOV13
Q54936981OVCA420
Q54936983OVCA429
Q54936988OVCA432
Q54936989OVCA433
Q50432263SK-OV-3

cites work (P2860)
Q3876696517 β-Estradiol Reverses Leptin-Inducing Ovarian Cancer Cell Migration by the PI3K/Akt Signaling Pathway
Q548592102,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibits human ovarian cancer cell proliferation.
Q33642960A bifunctional platinum(II) antitumor agent that forms DNA adducts with affinity for the estrogen receptor
Q49359257A computational based approach to identify estrogen receptor alpha/beta heterodimer selective ligands
Q43755070Aberrant promoter methylation of multiple genes in malignant ovarian tumors and in ovarian tumors with low malignant potential
Q36840255Aberrant transforming growth factor beta1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer
Q39028384Active Estrogen Receptor-alpha Signaling in Ovarian Cancer Models and Clinical Specimens
Q36447431Administration of glucocorticoids to ovarian cancer patients is associated with expression of the anti-apoptotic genes SGK1 and MKP1/DUSP1 in ovarian tissues
Q40749668Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 deletion variant in malignant human ovarian, prostate, and breast cancer cell lines.
Q37194722An endogenous aryl hydrocarbon receptor ligand inhibits proliferation and migration of human ovarian cancer cells
Q34345107Androgen receptor cytosine, adenine, guanine repeats, and haplotypes in relation to ovarian cancer risk
Q39188061Androgen receptor protein levels are significantly reduced in serous ovarian carcinomas compared with benign or borderline disease but are not altered by cancer stage or metastatic progression
Q24791470Animal models of ovarian cancer
Q34556898Application of phi29 motor pRNA for targeted therapeutic delivery of siRNA silencing metallothionein-IIA and survivin in ovarian cancers
Q36152737Bisphenol A and hormone-associated cancers: current progress and perspectives
Q34608699Characterization of ascites-derived ovarian tumor cells from spontaneously occurring ovarian tumors of the chicken: evidence for E-cadherin upregulation
Q42487014Characterization of calcium-mobilizing, purinergic P2Y(2) receptors in human ovarian cancer cells
Q34062570Chk1 inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers
Q38864663Cisplatin-, Doxorubicin-, and Docetaxel-Induced Cell Death Promoted by the Aqueous Extract of Solanum nigrum in Human Ovarian Carcinoma Cells.
Q37424155Combined application of 17beta-estradiol and progesterone enhance vascular endothelial growth factor and surfactant protein expression in cultured embryonic lung cells of mice
Q33767047DNA copy numbers profiles in affinity-purified ovarian clear cell carcinoma
Q34595670Decreased progesterone receptor isoform expression in luteal phase fallopian tube epithelium and high-grade serous carcinoma
Q38363908Differential expression of progesterone receptor isoforms A and B in the normal ovary, and in benign, borderline, and malignant ovarian tumors
Q34546378Differentially androgen-modulated genes in ovarian epithelial cells from BRCA mutation carriers and control patients predict ovarian cancer survival and disease progression
Q58325237Discrimination between serous low malignant potential and invasive epithelial ovarian tumors using molecular profiling
Q37143825Do Estrogen Receptor beta Polymorphisms Play A Role in the Pharmacogenetics of Estrogen Signaling?
Q43790618ER-dependent estrogenic activity of parabens assessed by proliferation of human breast cancer MCF-7 cells and expression of ERalpha and PR.
Q35855100Early alterations in ovarian surface epithelial cells and induction of ovarian epithelial tumors triggered by loss of FSH receptor
Q38873842Effects of bisphenol A and 17β-estradiol on vascular endothelial growth factor A and its receptor expression in the non-cancer and cancer ovarian cell lines.
Q36665020Emerging significance of ER-coregulator PELP1/MNAR in cancer
Q92702483Epigenetic Dysregulation at the Crossroad of Women's Cancer
Q37332214Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells
Q40790462Establishment and characterization of an immortalized human oviductal cell line.
Q37379821Estradiol 17β and its metabolites stimulate cell proliferation and antagonize ascorbic acid-suppressed cell proliferation in human ovarian cancer cells
Q34249388Estrogen and androgen receptor expression in surface epithelium and inclusion cyst in the ovary of premenopausal and postmenopausal women
Q89842725Estrogen enhances the proliferation and migration of ovarian cancer cells by activating transient receptor potential channel C3
Q28109453Estrogen receptor beta and ovarian cancer: a key to pathogenesis and response to therapy
Q35929364Estrogen receptor beta, a possible tumor suppressor involved in ovarian carcinogenesis
Q33642747Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha.
Q34022694Estrogen signaling crosstalk: Implications for endocrine resistance in ovarian cancer
Q73566195Estrogen stimulation of ovarian surface epithelial cell proliferation
Q24805637Estrogen, progesterone and epithelial ovarian cancer
Q46418281Estrogen-induced loss of progesterone receptor expression in normal and malignant ovarian surface epithelial cells
Q35840390Estrogens and epithelial ovarian cancer
Q34579904Exploiting MEK inhibitor-mediated activation of ERα for therapeutic intervention in ER-positive ovarian carcinoma
Q34056207Expression and function of androgen receptor coactivator p44/Mep50/WDR77 in ovarian cancer
Q43545822Expression of RFG/ELE1alpha/ARA70 in normal and malignant prostatic epithelial cell cultures and lines: regulation by methylation and sex steroids
Q40446182Expression of estrogen receptor-related receptors, a subfamily of orphan nuclear receptors, as new tumor biomarkers in ovarian cancer cells
Q53482030Expression of gonadal steroid receptors in the ovaries of post-menopausal women with malignant or benign endometrial pathology: a pilot study.
Q34200707Expression of membrane progesterone receptors (mPR/PAQR) in ovarian cancer cells: implications for progesterone-induced signaling events
Q34223682Expression of mitochondrial regulators PGC1α and TFAM as putative markers of subtype and chemoresistance in epithelial ovarian carcinoma
Q45274570Expression of progesterone receptor is a favorable prognostic marker in ovarian cancer
Q46403948Expression of steroid hormone receptors in BRCA1-associated ovarian carcinomas
Q58710004Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer
Q57492362Fertility Enhancement but Premature Ovarian Failure in -Deficient Female Zebrafish
Q37091852Gene expression analyses support fallopian tube epithelium as the cell of origin of epithelial ovarian cancer
Q36583705Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators.
Q37035786Gonadotropin-releasing hormone in the ovary
Q33820206HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation
Q40779150High-dose progesterone inhibition of urokinase secretion and invasive activity by SKOV-3 ovarian carcinoma cells: evidence for a receptor-independent nongenomic effect on the plasma membrane
Q37624838Highly and moderately aggressive mouse ovarian cancer cell lines exhibit differential gene expression
Q33647661Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer
Q26751021Hormone Receptors in Serous Ovarian Carcinoma: Prognosis, Pathogenesis, and Treatment Considerations
Q80552811Hormone replacement therapy and ovarian cancer risk: a meta-analysis
Q36966197Hormone response in ovarian cancer: time to reconsider as a clinical target?
Q46232798Human chorionic gonadotropin suppresses ovarian epithelial neoplastic cell proliferation in vitro
Q35787316Human ovarian cancer stem/progenitor cells are stimulated by doxorubicin but inhibited by Mullerian inhibiting substance
Q78454473IL-1alpha gene expression in human endometrial cancer is independent of ovarian steroid receptor expression
Q28304574Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling
Q34577355Identification of ovarian cancer associated genes using an integrated approach in a Boolean framework.
Q96952577Identification of ovarian high-grade serous carcinoma cell lines that show estrogen-sensitive growth as xenografts in immunocompromised mice
Q33986711Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival
Q36948026Increased proteasome-dependent degradation of estrogen receptor-alpha by TGF-beta1 in breast cancer cell lines
Q33963529Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells
Q36413695Integrative transcriptomics-based identification of cryptic drivers of taxol-resistance genes in ovarian carcinoma cells: Analysis of the androgen receptor
Q35600183Local estrogen metabolism in epithelial ovarian cancer suggests novel targets for therapy
Q35888377Loss of ERbeta expression as a common step in estrogen-dependent tumor progression
Q97539631Loss of progesterone receptor through epigenetic regulation is associated with poor prognosis in solid tumors
Q92071291Menopausal Hormone Replacement Therapy and the Risk of Ovarian Cancer: A Meta-Analysis
Q43864747Menopausal hormone therapy and risk of ovarian cancer in the European prospective investigation into cancer and nutrition
Q36643725Methylation status of oestrogen receptor-alpha gene promoter sequences in human ovarian epithelial cell lines
Q37888659Molecular targeted therapy in ovarian cancer: what is on the horizon?
Q90317700Natural history of ovarian high-grade serous carcinoma from time effects of ovulation inhibition and progesterone clearance of p53-defective lesions
Q35620640Oral contraceptive use and reproductive factors and risk of ovarian cancer in the European Prospective Investigation into Cancer and Nutrition
Q35552356Ovarian cancer and high-risk women—implications for prevention, screening, and early detection
Q35983656Pathophysiological dynamics of human ovarian surface epithelial cells in epithelial ovarian carcinogenesis
Q35178056Preclinical evaluation on the tumor suppression efficiency and combination drug effects of fermented wheat germ extract in human ovarian carcinoma cells
Q38321797Profiling estrogen-regulated gene expression changes in normal and malignant human ovarian surface epithelial cells.
Q46141026Prognostic value of estrogen receptor and progesterone receptor status in young Chinese ovarian carcinoma patients
Q33829679Prognostic value of progesterone receptor expression in ovarian cancer: a meta-analysis
Q53367630Recurrent copy number alterations in BRCA1-mutated ovarian tumors alter biological pathways.
Q33623349Relationship between epidemiologic risk factors and hormone receptor expression in ovarian cancer: results from the Nurses' Health Study
Q43597404Relationship between expression of coactivators and corepressors of hormone receptors and resistance of ovarian cancers to growth regulation by steroid hormones
Q34764768Risk factors for ovarian cancer: an overview with emphasis on hormonal factors
Q36703049Role of endocrine and growth factors on the ovarian surface epithelium.
Q39915688ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function
Q36243394Sex Steroid Hormone Receptor Expression Affects Ovarian Cancer Survival
Q38939445Stability, permeability and growth-inhibitory properties of gonadotropin-releasing hormone liposaccharides
Q38320209Structurally similar estradiol analogs uniquely alter the regulation of intracellular signaling pathways
Q50107365Targeting estrogen receptor beta (ERβ) for treatment of ovarian cancer: importance of KDM6B and SIRT1 for ERβ expression and functionality
Q39268041Tectorigenin sensitizes paclitaxel-resistant human ovarian cancer cells through downregulation of the Akt and NFκB pathway
Q64245953The Role of Androgen Receptor Signaling in Ovarian Cancer
Q39309057The association between reproductive and hormonal factors and ovarian cancer by estrogen-α and progesterone receptor status
Q37695280The carcinogenicity of dietary acrylamide intake: a comparative discussion of epidemiological and experimental animal research.
Q35646553The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis
Q36623704The human ovarian surface epithelium is an androgen responsive tissue
Q73135110The oestrogen receptor (ER) in vulva, vagina and ovary
Q36169983The progesterone receptor PROGINS polymorphism is not related to oxidative stress factors in women with polycystic ovary syndrome
Q36796735The role of activin A and Akt/GSK signaling in ovarian tumor biology
Q26786826The role of reproductive hormones in epithelial ovarian carcinogenesis
Q24316645Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transition
Q46545456Tumor suppressor and growth regulatory genes are overexpressed in severe early-onset preeclampsia--an array study on case-specific human preeclamptic placental tissue
Q24815527WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome

Search more.