Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo

scientific article

Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.191.10.1661
P932PMC publication ID2193147
P698PubMed publication ID10811860
P5875ResearchGate publication ID236238726

P50authorLuigina RomaniQ37386517
P2093author name stringC Montagnoli
A Bacci
A Mencacci
A Spreca
C F d'Ostiani
G Del Sero
P Ricciardi-Castagnoli
P2860cites workDendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial productsQ24678867
Dendritic cells and the control of immunityQ27860918
The mannose receptor is a pattern recognition receptor involved in host defenseQ28266161
Mechanisms of host defense against Candida species. I. Phagocytosis by monocytes and monocyte-derived macrophagesQ28301343
Nonfilamentous C. albicans mutants are avirulentQ29617839
Mechanisms of phagocytosis in macrophagesQ29618100
The dendritic cell system and its role in immunogenicityQ29619870
The Toll-receptor family and control of innate immunityQ33536547
Regulatory networks controlling Candida albicans morphogenesisQ33702252
The role of dendritic cells in the induction and regulation of immunity to microbial infection.Q33711401
Receptor mediated subversion of macrophage cytokine production by intracellular pathogens.Q33711413
Immunity to Candida albicans: Th1, Th2 cells and beyond.Q33718345
Characteristics of invasive candidiasis in gamma interferon- and interleukin-4-deficient mice: role of macrophages in host defense against Candida albicansQ33752636
Molecular characterization of the human macrophage mannose receptor: demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in Cos-1 cellsQ34269349
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processingQ34310837
In vitro susceptibility of fungi to killing by neutrophil granulocytes discriminates between primary pathogenicity and opportunismQ34534366
Distinct dendritic cell subsets differentially regulate the class of immune response in vivoQ34950113
CD4+ T-helper-cell responses in mice with low-level Candida albicans infection.Q35530617
Involvement of mannose receptor in cytokine interleukin-1beta (IL-1beta), IL-6, and granulocyte-macrophage colony-stimulating factor responses, but not in chemokine macrophage inflammatory protein 1beta (MIP-1beta), MIP-2, and KC responses, caused bQ35544447
Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cellsQ36066835
The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cellsQ36231530
Phagocytosis of antigens by Langerhans cells in vitroQ36362124
CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivoQ36367705
Antigen-pulsed CD8alpha+ dendritic cells generate an immune response after subcutaneous injection without homing to the draining lymph node.Q36367734
Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalizationQ36367948
Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cellsQ36375116
Regulation of interleukin-12 by complement receptor 3 signalingQ36377284
Measles virus suppresses cell-mediated immunity by interfering with the survival and functions of dendritic and T cellsQ36380589
Genetic regulation of commitment to interleukin 4 production by a CD4(+) T cell-intrinsic mechanismQ36401375
Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunityQ36404267
Fc receptor and complement receptor-mediated phagocytosis in host defence.Q36620223
Coiling phagocytosis of trypanosomatids and fungal cells.Q39572883
Host/pathogen interactions. Subversion of the mammalian cell cytoskeleton by invasive bacteriaQ39784118
Early differential molecular response of a macrophage cell line to yeast and hyphal forms of Candida albicansQ40148786
A TH1-TH2-like switch in candidiasis: new perspectives for therapy.Q40466988
The role of cell-mediated immunity in candidiasisQ40704101
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
Interaction of the fungal pathogen Candida albicans with integrin CD11b/CD18: recognition by the I domain is modulated by the lectin-like domain and the CD18 subunit.Q40991611
IL12 in Candida albicans infections.Q41137299
Interleukin-12 gene-expression of macrophages is regulated by nitric oxideQ41185978
Different cytokines regulate antigen uptake and presentation of a precursor dendritic cell lineQ41225268
Biological role of Th cell subsets in candidiasisQ41231632
Establishment of a cell line with features of early dendritic cell precursors from fetal mouse skinQ41316011
Growth inhibition of Candida albicans hyphae by CD8+ lymphocytesQ41345497
The T cell response against fungal infectionsQ41587158
Initiation of T-helper cell immunity to Candida albicans by IL-12: the role of neutrophilsQ41610649
IL-12 is both required and prognostic in vivo for T helper type 1 differentiation in murine candidiasis.Q43481185
Invasive candida infections--evolution of a fungal pathogenQ43701986
Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania majorQ43837143
Paclitaxel enhances macrophage IL-12 production in tumor-bearing hosts through nitric oxideQ44861283
Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice.Q44867018
Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicansQ44907215
Mannose receptor-mediated uptake of antigens strongly enhances HLA class II-restricted antigen presentation by cultured dendritic cells.Q52041455
Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1.Q52529254
Definition of dendritic cell subpopulations present in the spleen, Peyer's patches, lymph nodes, and skin of the mouseQ58436660
Innate and adaptive immunity to Candida albicans: A new view of an old paradigmQ58855410
Specific and non-specific immunity to Candida albicans a lesson from genetically modified animalsQ58855415
An immunoregulatory role for neutrophils in CD4+ T helper subset selection in mice with candidiasisQ58855421
Interleukin-12 but not interferon-γ production correlates with induction of T helper type-1 phenotype in murine candidiasisQ58855430
The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivityQ59564566
Stimulation of oxidative metabolism in murine polymorphonuclear leukocytes by unopsonized fungal cells: evidence for a mannose-specific mechanismQ70161146
Interactions of Candida albicans Yeast Cells, Germ Tubes and Hyphae with Human Polymorphonuclear Leucocytes in vitroQ70214056
Chronic mucocutaneous candidiasis. I. Altered antigen-stimulated IL-2, IL-4, IL-6 and interferon-gamma (IFN-gamma) productionQ71254982
Human dendritic cells phagocytose and process Borrelia burgdorferiQ71555606
Modulation of Macrophage Phagocytic Activity by Cell Wall Components of Candida albicansQ72013441
Rapid recruitment of late endosomes and lysosomes in mouse macrophages ingesting Candida albicansQ73036167
Allergenicity of acid protease secreted by Candida albicansQ73039735
Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodesQ73500921
Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan: mannose receptor-mediated phagocytosis initiates IL-12 productionQ73648229
Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnoverQ74303609
Dendritic cellsQ74353968
Reciprocal control of T helper cell and dendritic cell differentiationQ74452751
Candida albicans hyphal formation and virulence: is there a clearly defined role?Q74533074
The role of tumor necrosis factor alpha in modulating the quantity of peripheral blood-derived, cytokine-driven human dendritic cells and its role in enhancing the quality of dendritic cell function in presenting soluble antigens to CD4+ T cells inQ74620494
Coiling phagocytosis: when the zipper jams, the cup is deformedQ77529499
Retrovirally induced switch from production of IL-12 to IL-4 in dendritic cellsQ78066630
IL-12 acts selectively on CD8 alpha- dendritic cells to enhance presentation of a tumor peptide in vivoQ78224712
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectCandida albicansQ310443
dendritic cellQ506253
P304page(s)1661-1674
P577publication date2000-05-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleDendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo
P478volume191