Cellular homologue (c-src) of the transforming gene of Rous sarcoma virus: isolation, mapping, and transcriptional analysis of c-src and flanking regions

scientific article published on September 1, 1981

Cellular homologue (c-src) of the transforming gene of Rous sarcoma virus: isolation, mapping, and transcriptional analysis of c-src and flanking regions is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1981PNAS...78.5842P
P356DOI10.1073/PNAS.78.9.5842
P953full work available at URLhttps://europepmc.org/articles/PMC348882
https://europepmc.org/articles/PMC348882?pdf=render
https://pnas.org/doi/pdf/10.1073/pnas.78.9.5842
P932PMC publication ID348882
P698PubMed publication ID6272320
P5875ResearchGate publication ID16924598

P50authorHarold E. VarmusQ295691
J. Michael BishopQ311358
P2093author name stringR. C. Parker
P2860cites workUninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src)Q24597268
Hybridization of denatured RNA and small DNA fragments transferred to nitrocelluloseQ24611198
Detection of specific sequences among DNA fragments separated by gel electrophoresisQ25939003
Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene productQ28263712
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebratesQ28776303
The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNAQ29547602
Isolation of the chicken β-globin gene and a linked embryonic β-like globin gene from a chicken DNA recombinant libraryQ31161619
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNAQ34581419
Nucleotide sequence of the rightward operator of phage lambdaQ35074385
Molecular cloning and characterization of avian sarcoma virus circular DNA moleculesQ36506123
Human oncovirologyQ37987947
Identification of a transformation-specific antigen induced by an avian sarcoma virusQ40101156
Characteristics of cellular RNA related to the transforming gene of avian sarcoma virusesQ40128409
Mapping unintegrated avian sarcoma virus DNA: Termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNAQ40196888
Restriction endonuclease cleavage maps of rat and mouse mitochondrial DNAsQ40581569
Properties of a Normal Mouse Cell DNA Sequence (sarc) Homologous to the src Sequence of Moloney Sarcoma VirusQ42828752
A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virusQ45801484
onc sequences (v-fes) of Snyder–Theilen feline sarcoma virus are derived from noncontiguous regions of a cat cellular gene (c-fes)Q45802476
Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNAQ45802663
The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletionsQ47617863
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosisQ53571550
Two-dimensional agarose gel electrophoresis "SeaPlaque" agarose dimension.Q54309750
Organization of Endogenous and Exogenous Viral and Linked Nonviral SequencesQ58171182
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectRous sarcoma virusQ1444330
viral transformationQ17162815
viral genesQ71237937
P304page(s)5842-5846
P577publication date1981-09-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleCellular homologue (c-src) of the transforming gene of Rous sarcoma virus: isolation, mapping, and transcriptional analysis of c-src and flanking regions
P478volume78

Reverse relations

cites work (P2860)
Q35610574Activation of the transforming potential of p60c-src by a single amino acid change
Q33264705Analysis of cDNAs of the proto-oncogene c-src: heterogeneity in 5' exons and possible mechanism for the genesis of the 3' end of v-src
Q40872306Biochemical markers for colorectal cancer. Diagnostic and therapeutic implications
Q26769907CRISPR/Cas9 and cancer targets: future possibilities and present challenges
Q36924864DNA sequence of the viral and cellular src gene of chickens. II. Comparison of the src genes of two strains of avian sarcoma virus and of the cellular homolog
Q40135025Defective Avian Sarcoma Viruses
Q42355775Editorial comment: cancer biology--lessons learned from sarcoma
Q45798470Effect of several nucleotides on the phosphorylating activities of the Rous-sarcoma-virus transforming protein pp60v-sic and its cellular homologue, pp60c-sic
Q36944224Expression of the Chicken c-src Gene in COS Cells
Q36926920FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA
Q35130695Genetic and cytogenetic analyses of breast cancer yield different perspectives of a complex disease
Q35686551High spontaneous mutation rate of Rons sarcoma virus demonstrated by direct sequencing of the RNA genome
Q34469297Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src
Q24630068Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses
Q34055226Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29
Q45800564Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus
Q36422848Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus
Q24618042Isolation of duplicated human c-src genes located on chromosomes 1 and 20
Q59080848Loss of intervening sequences in genomic mouse α-globin DNA inserted in an infectious retrovirus vector
Q36309769Molecular cloning and chromosomal mapping of a human locus related to the transforming gene of Moloney murine sarcoma virus
Q36624033Nobel lecture. Retroviruses and oncogenes. I.
Q24298621Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin
Q34253626Nucleotide Sequence of the Oncogene Encoding the p21 Transforming Protein of Kirsten Murine Sarcoma Virus
Q24300883Nucleotide sequences of feline retroviral oncogenes (v-fes) provide evidence for a family of tyrosine-specific protein kinase genes
Q54082559Oncogenes and linkage groups: conservation during mammalian chromosome evolution.
Q37577123Overexpression of the c-src protein does not induce transformation of NIH 3T3 cells
Q36381266Protein kinase Calpha and epsilon small-molecule targeted therapeutics: a new roadmap to two Holy Grails in drug discovery?
Q27009016Roles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implications
Q36272657Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts
Q34103644Selected glimpses into the activation and function of Src kinase
Q36598671Structural organization and expression of human DNA sequences related to the transforming gene of avian myeloblastosis virus
Q36912175Structure and dimorphism of c-rel (turkey), the cellular homolog to the oncogene of reticuloendotheliosis virus strain T.
Q36928811Structure and expression of c-rel, the cellular homolog to the oncogene of reticuloendotheliosis virus strain T
Q34254297Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus
Q36905370Structure and transcription of the cellular homolog (c-myb) of the avian myeloblastosis virus transforming gene (v-myb).
Q35832019The aortic ring model of angiogenesis: a quarter century of search and discovery
Q40130033The molecular understanding of cancer: from the unspeakable illness to a curable disease
Q36939754Transcription of c-onc genes c-rasKi and c-fms during mouse development
Q28265321Transduction of a cellular oncogene: the genesis of Rous sarcoma virus
Q36874621Transduction of proto-src sequences in tissue culture by a molecular clone of transformation-defective Rous sarcoma virus with an internal src deletion.
Q37601341Tumor induction by direct injection of cloned v-src DNA into chickens
Q24654769Two adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinase
Q35589206Tyrosine kinase inhibitors as cancer therapy
Q39493619Viruses, genes, and cancer. I. The discovery of cellular oncogenes and their role in neoplasia