Dysregulated co-stimulatory molecule expression in a Sjögren's syndrome mouse model with potential implications by microRNA-146a

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Dysregulated co-stimulatory molecule expression in a Sjögren's syndrome mouse model with potential implications by microRNA-146a is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MOLIMM.2015.09.027
P932PMC publication ID4679674
P698PubMed publication ID26505653

P2093author name stringQing Yu
Seunghee Cha
Carol M Stewart
Gautam Nayar
Yun-Jong Park
Adrienne E Gauna
Jun-o Jin
Marelys Onate
P2860cites workNF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responsesQ24670080
Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cellsQ27340853
PD-1 and its ligands in tolerance and immunityQ28131650
AU-rich elements: characterization and importance in mRNA degradationQ29547896
Molecular dynamics simulations of Ago silencing complexes reveal a large repertoire of admissible 'seed-less' targets.Q34293710
MicroRNA-146a in autoimmunity and innate immune responses.Q34318595
Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseasesQ34615216
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responsesQ34650346
MicroRNA-146a is upregulated by and negatively regulates TLR2 signaling.Q34701099
Progress in understanding autoimmune exocrinopathy using the non-obese diabetic mouse: an updateQ34720542
What's the difference between CD80 and CD86?Q35155949
Glandular and extraglandular expression of costimulatory molecules in patients with Sjögren's syndromeQ35550391
Inflammatory caspases are critical for enhanced cell death in the target tissue of Sjögren's syndrome before disease onsetQ35765504
Local delivery of AAV2-CTLA4IgG decreases sialadenitis and improves gland function in the C57BL/6.NOD-Aec1Aec2 mouse model of Sjögren's syndromeQ36085054
miR-146a controls the resolution of T cell responses in miceQ36193546
MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjögren's syndromeQ36841784
MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in miceQ36864863
Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patientsQ36955334
Altered miR-146a expression in Sjögren's syndrome and its functional role in innate immunityQ37140499
microRNAs and the immune responseQ37178538
MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cellsQ37263163
Revisiting the principles of microRNA target recognition and mode of actionQ37368876
The role of intrinsic epithelial activation in the pathogenesis of Sjögren’s syndromeQ37777764
Cellular microRNAs (miRNAs) and Sjögren's syndrome: candidate regulators of autoimmune response and autoantigen expressionQ37883679
The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancerQ37997552
MicroRNA involvement in lupus: the beginning of a new taleQ38021618
The emerging role of microRNAs in the pathogenesis of systemic lupus erythematosusQ38109412
Isolation of mouse salivary gland stem cellsQ38763879
Functional expression of a costimulatory B7.2 (CD86) protein on human salivary gland epithelial cells that interacts with the CD28 receptor, but has reduced binding to CTLA4.Q40826690
Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sjögren's syndromeQ40972080
The BB1 monoclonal antibody recognizes both cell surface CD74 (MHC class II-associated invariant chain) as well as B7-1 (CD80), resolving the question regarding a third CD28/CTLA-4 counterreceptorQ41007929
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responsesQ44393406
Minor salivary gland involvement in Sjögren's syndromeQ45065171
CD28 costimulation: walking the immunological tightropeQ45743806
CD86 and CD80 differentially modulate the suppressive function of human regulatory T cellsQ47192084
Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86.Q51807589
Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells.Q51842808
Circulating microRNA expression profiles associated with systemic lupus erythematosus.Q54272397
Early pathogenic events associated with Sjögren's syndrome (SjS)-like disease of the NOD mouse using microarray analysis.Q54573527
Salivary gland epithelial cells (SGEC): carriers of exquisite B7-2 (CD86) costimulatory moleculesQ56899321
Treatment with anti-CD86 costimulatory molecule prevents the autoimmune lesions in murine Sjögren's syndrome (SS) through up-regulated Th2 responseQ73348120
Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjögren's syndrome) on a healthy murine backgroundQ74455359
The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritisQ83676869
P4510describes a project that usesImageJQ1659584
P433issue2 Pt C
P407language of work or nameEnglishQ1860
P921main subjectSjögren's syndromeQ335555
P304page(s)606-616
P577publication date2015-10-21
P1433published inMolecular ImmunologyQ6895954
P1476titleDysregulated co-stimulatory molecule expression in a Sjögren's syndrome mouse model with potential implications by microRNA-146a
P478volume68

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cites work (P2860)
Q64946980Analysis of differentially expressed microRNA of TNF-α-stimulated mesenchymal stem cells and exosomes from their culture supernatant.
Q42045034Leptin/OB-R pathway promotes IL-4 secretion from B lymphocytes and induces salivary gland epithelial cell apoptosis in Sjögren's syndrome
Q57471217MicroRNAs in Autoimmunity and Hematological Malignancies
Q38370521Relationship of miRNA-146a to primary Sjögren's syndrome and to systemic lupus erythematosus: a meta-analysis.

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