| scholarly article | Q13442814 |
| P50 | author | Daniel Altmann | Q41433034 |
| David D Brand | Q56999832 | ||
| P2093 | author name string | D M Zaller | |
| A H Kang | |||
| A Woods | |||
| J M Stuart | |||
| E F Rosloniec | |||
| L K Myers | |||
| K B Whittington | |||
| M Gumanovskaya | |||
| P2860 | cites work | Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays | Q25939005 |
| The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis | Q28306666 | ||
| Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability | Q29617252 | ||
| Persistence of collagen type II-specific T-cell clones in the synovial membrane of a patient with rheumatoid arthritis | Q33832421 | ||
| HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region | Q34326526 | ||
| Genetic and environmental factors in the immune pathogenesis of rheumatoid arthritis | Q35155210 | ||
| The genetic basis of rheumatoid arthritis. The shared epitope hypothesis | Q35155219 | ||
| Autoimmunity to type II collagen an experimental model of arthritis | Q36335891 | ||
| Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition | Q36344766 | ||
| Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates | Q36345534 | ||
| Type II collagen-induced arthritis in rats. Passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis | Q36346088 | ||
| Induction of arthritis in monkeys by immunization with type II collagen | Q36355205 | ||
| The T cell response of HLA-DR transgenic mice to human myelin basic protein and other antigens in the presence and absence of human CD4. | Q36364563 | ||
| HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis | Q36366088 | ||
| Sequence homology and immunologic cross-reactivity of human cytomegalovirus with HLA-DR beta chain: a means for graft rejection and immunosuppression | Q36825746 | ||
| MHC and autoimmune diseases: susceptibility to rheumatoid arthritis associated with a hydrophobic strip of alpha helix encoded by several MHC alleles | Q37526113 | ||
| Immune response of HLA-DQ8 transgenic mice to peptides from the third hypervariable region of HLA-DRB1 correlates with predisposition to rheumatoid arthritis | Q37702346 | ||
| The Epstein-Barr virus glycoprotein gp110, a molecular link between HLA DR4, HLA DR1, and rheumatoid arthritis | Q38187718 | ||
| The Human Immune Response Region (HLA-D) and Disease Susceptibility | Q40146421 | ||
| Identification of MHC class II and TCR binding residues in the type II collagen immunodominant determinant mediating collagen-induced arthritis | Q41173522 | ||
| Species-specific binding of CD4 to the beta 2 domain of major histocompatibility complex class II molecules | Q41821340 | ||
| Human major histocompatibility complex class II-restricted T cell responses in transgenic mice | Q42942451 | ||
| A CD4 cell is capable of transferring suppression of collagen-induced arthritis. | Q44359227 | ||
| HLA genes associated with rheumatoid arthritis. Identification of susceptibility alleles using specific oligonucleotide probes | Q44999242 | ||
| Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine alpha 1(II)-CB11 in H-2q mice | Q48084198 | ||
| Two better cell lines for making hybridomas expressing specific T cell receptors. | Q48287125 | ||
| Specificity of an HLA-DRB1*0401-restricted T cell response to type II collagen. | Q52307926 | ||
| Properties of Antigen-Specific H-2 Restricted T Cell Hybridomas | Q56922624 | ||
| A Structural Model for TCR Recognition of the HLA Class II Shared Epitope Sequence Implicated in Susceptibility to Rheumatoid Arthritis | Q57159097 | ||
| Immunisation against heterologous type II collagen induces arthritis in mice | Q59053172 | ||
| Specificity of antibodies to type II collagen in rheumatoid arthritis | Q67674031 | ||
| Multi-pin peptide synthesis strategy for T cell determinant analysis | Q67674727 | ||
| HLA-DR4 and other genetic markers in rheumatoid arthritis | Q68096297 | ||
| Serum IgG anti-native type II collagen antibodies in rheumatoid arthritis: association with HLA DR4 and lack of clinical correlation | Q68102843 | ||
| Analysis of the molecular specificities of anti-class II monoclonal antibodies by using L cell transfectants expressing HLA class II molecules | Q69042057 | ||
| Sex-linked differences in susceptibility of cynomolgus monkeys to type II collagen-induced arthritis. Evidence that epitope-specific immune suppression is involved in the regulation of type II collagen autoantibody formation | Q69077861 | ||
| Immune responses in vitro. I. Culture conditions for antibody synthesis | Q69161651 | ||
| The MHC-binding and gp120-binding functions of CD4 are separable | Q69355384 | ||
| Assessment of the potential pathogenicity of type II collagen autoantibodies in patients with rheumatoid arthritis. Evidence of restricted IgG3 subclass expression and activation of complement C5 to C5a | Q69657958 | ||
| Autoantibody specificities of immune complexes sequestered in articular cartilage of patients with rheumatoid arthritis and osteoarthritis | Q70080495 | ||
| A Case of Germinal Center Formation by CD45RO T and CD20 B Lymphocytes in Rheumatoid Arthritic Subchondral Bone: Proposal for a Two-Compartment Model of Immune-Mediated Disease with Implications for Immunotherapeutic Strategies | Q71649521 | ||
| Could HLA-DRB1 be the protective locus in rheumatoid arthritis? | Q71708457 | ||
| Incidence and specificity of antibodies to types I, II, III, IV, and V collagen in rheumatoid arthritis and other rheumatic diseases as measured by125i-radioimmunoassay | Q72704685 | ||
| Isolation and characterization of the cyanogen bromide peptides from the l(II) chain of chick cartilage collagen | Q95788346 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1113-1122 | |
| P577 | publication date | 1997-03-01 | |
| P1433 | published in | Journal of Experimental Medicine | Q3186912 |
| P1476 | title | An HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen | |
| P478 | volume | 185 |
| Q41782459 | A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II molecule |
| Q54123094 | A new categorization of HLA DR alleles on a functional basis. |
| Q34679722 | A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes. |
| Q34222660 | A role for calreticulin in the pathogenesis of rheumatoid arthritis |
| Q27481378 | A systematic bioinformatics approach for selection of epitope-based vaccine targets |
| Q91757270 | Ameliorating effects of Gö6976, a pharmacological agent that inhibits protein kinase D, on collagen-induced arthritis |
| Q35605653 | Analog peptides of type II collagen can suppress arthritis in HLA-DR4 (DRB1*0401) transgenic mice. |
| Q47555471 | Analysis of viral diversity for vaccine target discovery |
| Q33324394 | Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules |
| Q36376336 | Anergy in peripheral memory CD4(+) T cells induced by low avidity engagement of T cell receptor |
| Q73313513 | Antibodies to type II collagen and HLA disease susceptibility markers in rheumatoid arthritis |
| Q39776822 | Antigen processing of the heptavalent pneumococcal conjugate vaccine carrier protein CRM(197) differs depending on the serotype of the attached polysaccharide |
| Q24807019 | Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men |
| Q35823339 | Beryllium presentation to CD4+ T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease |
| Q37690636 | Characterization of T cell phenotype and function in a double transgenic (collagen-specific TCR/HLA-DR1) humanized model of arthritis. |
| Q42326335 | Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis |
| Q35475327 | Collagen type II and a thermo-responsive polymer of N-isopropylacrylamide induce arthritis independent of Toll-like receptors: a strong influence by major histocompatibility complex class II and Ncf1 genes |
| Q80422777 | Collagen-induced arthritis |
| Q42971869 | Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen. |
| Q36907623 | Comparative analysis of collagen type II-specific immune responses during development of collagen-induced arthritis in two B10 mouse strains. |
| Q27765717 | Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein |
| Q36476612 | Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis |
| Q36498837 | Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice. |
| Q37353611 | Design of peptide immunotherapies for MHC Class-II-associated autoimmune disorders |
| Q30978132 | Dissection of the genetic complexity of arthritis using animal models |
| Q42054161 | Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing |
| Q34561569 | Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources |
| Q39675520 | Effects of type II collagen epitope carbamylation and citrullination in human leucocyte antigen (HLA)-DR4(+) monozygotic twins discordant for rheumatoid arthritis. |
| Q39158358 | Engineered regulatory T cells coexpressing MHC class II:peptide complexes are efficient inhibitors of autoimmune T cell function and prevent the development of autoimmune arthritis |
| Q28476101 | Enhancement of tumour-specific immune responses in vivo by 'MHC loading-enhancer' (MLE) |
| Q61628140 | Evaluating candidate autoantigens in rheumatoid arthritis |
| Q52313895 | Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice. |
| Q77892061 | Genetics of susceptibility to chronic experimental encephalomyelitis and arthritis |
| Q37172531 | HLA class II transgenic mice mimic human inflammatory diseases. |
| Q33815475 | HLA class II transgenic mice: models of the human CD4+ T-cell immune response. |
| Q39799339 | HLA transgenic mice as humanized mouse models of disease and immunity. |
| Q34948997 | HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation |
| Q92089102 | Highly conserved influenza T cell epitopes induce broadly protective immunity |
| Q34212258 | Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization |
| Q34096264 | Human autoimmunity genes in mice |
| Q64228779 | Humanized Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Cell-Based Therapies |
| Q35754332 | Humanized animal models for autoimmune diseases |
| Q33554688 | Identification of HLA class II-restricted determinants of Mycobacterium tuberculosis-derived proteins by using HLA-transgenic, class II-deficient mice |
| Q44885833 | Identification of type II collagen peptide 261-273-specific T cell clones in a patient with relapsing polychondritis |
| Q24633296 | Immunogenicity of protein therapeutics: The key causes, consequences and challenges |
| Q48055351 | In Vivo Dual Fluorescence Imaging to Detect Joint Destruction. |
| Q40855997 | Induction of CTL response by a minimal epitope vaccine in HLA A*0201/DR1 transgenic mice: dependence on HLA class II restricted T(H) response. |
| Q44535197 | Induction of carbohydrate-specific antibodies in HLA-DR transgenic mice by a synthetic glycopeptide: a potential anti cancer vaccine for human use. |
| Q37384851 | Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice |
| Q44563812 | Inhibition of T-cell activation with HLA-DR1/DR4 restricted Non-T-cell stimulating peptides |
| Q45420244 | Inhibitory effects on HLA-DR1-specific T-cell activation by influenza virus haemagglutinin-derived peptides |
| Q45751487 | Involvement of autoimmunity against type II collagen in the development of arthritis in mice transgenic for the human T cell leukemia virus type I tax gene |
| Q89759416 | Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases |
| Q38207877 | Lymphocyte-based model systems for allergy research: a historic overview |
| Q36278295 | MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis |
| Q36430136 | MHC class II proteins and disease: a structural perspective |
| Q35107011 | MHC molecules in health and disease: At the cusp of a paradigm shift |
| Q35620743 | Mice lacking all conventional MHC class II genes |
| Q63433140 | Mouse models for rheumatoid arthritis |
| Q35156717 | New insights into the functional role of the rheumatoid arthritis shared epitope |
| Q52010918 | Novel promiscuous HLA-DQ HIV Nef peptide that induces IFN-gamma-producing memory CD4+ T cells. |
| Q33333935 | On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease |
| Q46937066 | Peptide-binding assays and HLA II transgenic Abeta degrees mice are consistent and complementary tools for identifying HLA II-restricted peptides. |
| Q38104674 | Preclinical models used for immunogenicity prediction of therapeutic proteins |
| Q31089923 | Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis |
| Q36735401 | Primer: comparative genetics of animal models of arthritis--a tool to resolve complexity |
| Q42061110 | Production of CD4⁺ and CD8⁺ T cell hybridomas |
| Q57536855 | Reply |
| Q42177520 | Resolution of infection promotes a state of dormancy and long survival of CD4 memory T cells. |
| Q24806869 | Rheumatoid arthritis viewed using a headache paradigm |
| Q33895804 | Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies |
| Q36288434 | Second-generation peptidomimetic inhibitors of antigen presentation effectively treat autoimmune diseases in HLA-DR-transgenic mouse models |
| Q55345808 | Shared epitope-aryl hydrocarbon receptor crosstalk underlies the mechanism of gene-environment interaction in autoimmune arthritis. |
| Q33258637 | Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket |
| Q27653688 | Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis |
| Q37651126 | Suboptimal engagement of the T-cell receptor by a variety of peptide-MHC ligands triggers T-cell anergy |
| Q36526075 | Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones |
| Q73954901 | Synthetic peptides that inhibit binding of the collagen type II 261-273 epitope to rheumatoid arthritis-associated HLA-DR1 and -DR4 molecules and collagen-specific T-cell responses |
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| Q39534685 | T cell hybridomas to study MHC-II restricted B-cell receptor-mediated antigen presentation by human B cells |
| Q41856587 | T cell responses to a non-glycosylated epitope predominate in type II collagen-immunised HLA-DRB1*0101 transgenic mice |
| Q24792514 | T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis |
| Q42395223 | T-cell immune adaptor SKAP1 regulates the induction of collagen-induced arthritis in mice |
| Q52370705 | Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues. |
| Q40117186 | The CII-specific autoimmune T-cell response develops in the presence of FTY720 but is regulated by enhanced Treg cells that inhibit the development of autoimmune arthritis. |
| Q36674612 | The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity |
| Q36638368 | The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN. |
| Q73838437 | The MHC is a major determinant of viral status, but not fibrotic stage, in individuals infected with hepatitis C |
| Q35165161 | The Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits gamma interferon-regulated HLA-DR and Fc gamma R1 on human macrophages through Toll-like receptor 2. |
| Q40059657 | The Role of Leukocyte-Associated Ig-like Receptor-1 in Suppressing Collagen-Induced Arthritis. |
| Q24805318 | The genetics of rheumatoid arthritis and the need for animal models to find and understand the underlying genes |
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| Q34067135 | The rheumatoid arthritis HLA-DRB1 shared epitope |
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| Q33458893 | The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis |
| Q34554029 | Transgenic models of autoimmune disease |
| Q33713326 | Transgenic mouse models of rheumatoid arthritis |
| Q35738486 | Use of Humanized Mice to Study the Pathogenesis of Autoimmune and Inflammatory Diseases |
| Q37150458 | Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis |
| Q27746792 | X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II |
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