ROS as signalling molecules in T cells--evidence for abnormal redox signalling in the autoimmune disease, rheumatoid arthritis

scientific article

ROS as signalling molecules in T cells--evidence for abnormal redox signalling in the autoimmune disease, rheumatoid arthritis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1179/135100005X83680
P698PubMed publication ID16438798

P2093author name stringHelen R Griffiths
P2860cites workA Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodesQ24291514
Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen speciesQ28174200
Mitochondrial free radical generation, oxidative stress, and agingQ29614202
Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domainQ30433525
S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells.Q33202580
Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunityQ33664752
Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2Q33861934
Localization of Th-cell subsets in inflammation: differential thresholds for extravasation of Th1 and Th2 cellsQ33877001
Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stressQ33994493
Inducible nitric oxide synthase in T cells regulates T cell death and immune memoryQ34380306
Structural, redox, and mechanistic parameters for cysteine-sulfenic acid function in catalysis and regulationQ34414537
Nitric oxide, mitochondria, and cell deathQ34499084
Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agentQ34501431
Cytokines in rheumatoid arthritisQ34637317
Biomarkers.Q34701833
Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function.Q34701848
Cell signalling and the glutathione redox systemQ34816510
Replicative senescence of CD8 T cells: effect on human ageingQ35721419
The Nox family of NAD(P)H oxidases: host defense and beyondQ35886272
T cell receptor stimulation, reactive oxygen species, and cell signalingQ35903068
Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patternsQ35979356
Regulation of the chemokine receptor CXCR4 by hypoxiaQ36371842
Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expressionQ36376476
Inhibition of T cell apoptosis in the rheumatoid synoviumQ39777667
2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process.Q40455972
Inducible nitric oxide synthase-mediated proliferation of a T lymphoma cell line.Q40666204
mRNA expression profile of a human cancer cell line in response to Ginkgo biloba extract: induction of antioxidant response and the Golgi systemQ40822585
Ceramide induces a loss in cytosolic peroxide levels in mononuclear cellsQ41910048
The intracellular oxidation of 2',7'-dichlorofluorescin in murine T lymphocytes.Q43514314
Cutting edge: T cell migration regulated by CXCR4 chemokine receptor signaling to ZAP-70 tyrosine kinaseQ43699029
Optimal chemotactic responses of leukemic T cells to stromal cell-derived factor-1 requires the activation of both class IA and IB phosphoinositide 3-kinases.Q44394542
Superoxide, H2O2, and iron are required for TNF-α-induced MCP-1 gene expression in endothelial cells: role of Rac1 and NADPH oxidaseQ44630332
Tyrosine phosphorylation-dependent activation of NFkappaB is compromised in T cells from the elderlyQ44818879
Mitochondrial free radical production and cell signalingQ44819896
Azelnidipine, a newly developed long-acting calcium antagonist, inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endothelial cells through its anti-oxidative propertiesQ44835411
Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cellsQ44947136
Rap1 signaling is required for suppression of Ras-generated reactive oxygen species and protection against oxidative stress in T lymphocytesQ44968886
Extra-cellular superoxide promotes T cell expansion through inactivation of nitric oxideQ44987209
Age-associated change in the frequency of memory CD4+ T cells impairs long term CD4+ T cell responses to influenza vaccineQ47309523
Topical glucocorticoid therapy directly induces up-regulation of functional CXCR4 on primed T lymphocytes in the aqueous humor of patients with uveitisQ47578531
CD28 co-stimulation is intact and contributes to prolonged ex vivo survival of hyporesponsive synovial fluid T cells in rheumatoid arthritisQ48035841
Tumour necrosis factor alpha (TNF-alpha) interferes with Fas-mediated apoptotic cell death on rheumatoid arthritis (RA) synovial cells: a possible mechanism of rheumatoid synovial hyperplasia and a clinical benefit of anti-TNF-alpha therapy for RA.Q50513699
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectrheumatoid arthritisQ187255
P304page(s)273-280
P577publication date2005-01-01
P1433published inRedox ReportQ15758836
P1476titleROS as signalling molecules in T cells--evidence for abnormal redox signalling in the autoimmune disease, rheumatoid arthritis
P478volume10

Reverse relations

cites work (P2860)
Q51764192Animal Toxins as Therapeutic Tools to Treat Neurodegenerative Diseases.
Q45328704Coenzyme Q10 benefits symptoms in Gulf War veterans: results of a randomized double-blind study
Q41449206Collaborative Power of Nrf2 and PPARγ Activators against Metabolic and Drug-Induced Oxidative Injury
Q36815232Contributions to our understanding of T cell physiology through unveiling the T cell proteome
Q28390378Copper-zinc superoxide dismutase-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis induced with myelin oligodendrocyte glycoprotein 35-55
Q41899040Cytochrome-P450 enzymes and autoimmunity: expansion of the relationship and introduction of free radicals as the link.
Q82563610ER stress, p66shc, and p-Akt/Akt mediate adjuvant-induced inflammation, which is blunted by argirein, a supermolecule and rhein in rats
Q55036970Effect of Chronic Oxidative Stress on Neuroinflammatory Response Mediated by CD4+T Cells in Neurodegenerative Diseases.
Q42430052Effects of Apium graveolens Extract on the Oxidative Stress in the Liver of Adjuvant-Induced Arthritic Rats
Q42494792Free radicals and redox signalling in T-cells during chronic inflammation and ageing
Q41911510Gingipains from Porphyromonas gingivalis increase the chemotactic and respiratory burst-priming properties of the 77-amino-acid interleukin-8 variant
Q36866499Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation
Q46914146Identification of clinical parameters associated with serum oxidative stress in patients with rheumatoid arthritis
Q28388335Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
Q23923177Mitochondrial targeting of electron scavenging antioxidants: regulation of selective oxidation vs random chain reactions
Q39429504Molecular Mechanisms behind Free Radical Scavengers Function against Oxidative Stress
Q89459546Novel Anti-arthritic Mechanisms of Polydatin in Complete Freund's Adjuvant-Induced Arthritis in Rats: Involvement of IL-6, STAT-3, IL-17, and NF-кB
Q35856966Novel role for mitochondria: protein kinase Ctheta-dependent oxidative signaling organelles in activation-induced T-cell death
Q37806960Oxidative mechanisms and atherothrombotic cardiovascular disease
Q33554184Oxidative risk for atherothrombotic cardiovascular disease
Q51401255Oxidative stress in systemic lupus erythematosus and rheumatoid arthritis patients: relationship to disease manifestations and activity.
Q37530475Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization.
Q45338276Redox Regulation of Inflammatory Processes Is Enzymatically Controlled.
Q37142186Redox signalling and the inflammatory response in rheumatoid arthritis.
Q37174493Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging
Q37280563Role of increased ROS dissipation in prevention of T1D.
Q80179225Serum oxidative-antioxidative status in patients with ankylosing spondilitis
Q36665312Simultaneous quantification of mitochondrial DNA damage and copy number in circulating blood: a sensitive approach to systemic oxidative stress
Q38977669Single-cell resolution of intracellular T cell Ca2+ dynamics in response to frequency-based H2O2 stimulation
Q89995936Stimuli-Responsive Delivery of Growth Factors for Tissue Engineering
Q34795739Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro
Q38961119Sumoylation Modulates the Susceptibility to Type 1 Diabetes.
Q35123480Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes
Q39366944The Potential of Circadian Realignment in Rheumatoid Arthritis
Q38569178Tumour, Oxidative Stress and Host T Cell Response: Cementing the Dominance

Search more.