Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human.

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Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0177928
P932PMC publication ID5435338
P698PubMed publication ID28545106

P50authorFlorian CaimentQ55274597
Theo M C M de KokQ55453416
Mark GosinkQ56946460
Julian KrauskopfQ88153803
P2093author name stringKent J Johnson
Roscoe L Warner
Deborah A Burt
Jiri Aubrecht
Jos C Kleinjans
Shelli J Schomaker
Patricia Chandler
P2860cites workCirculating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseasesQ36365092
Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitationsQ36693002
Identification of cardiac-related circulating microRNA profile in human chronic heart failureQ36729339
Role of B cells in antigen presentation of the hepatitis B coreQ36829085
Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicityQ37656707
Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?Q37981140
Diversifying microRNA sequence and functionQ38117040
Regulation of microRNA by hepatitis B virus infection and their possible association with control of innate immunity.Q38223363
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndromeQ38312576
Pancreas-enriched miRNAs are altered in the circulation of subjects with diabetes: a pilot cross-sectional study.Q39456074
Elevated Hepatic miR-22-3p Expression Impairs Gluconeogenesis by Silencing the Wnt-Responsive Transcription Factor Tcf7.Q40716224
Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target GenesQ41549935
miR-125b inhibits hepatitis B virus expression in vitro through targeting of the SCNN1A geneQ42195546
Extracellular miRNAs: the mystery of their origin and functionQ44235487
Circulating miRNAs as potential biomarkers in Alzheimer's diseaseQ44261737
Profiling of circulating microRNAs reveals common microRNAs linked to type 2 diabetes that change with insulin sensitization.Q51327695
Circulating microRNAs as potential markers of human drug-induced liver injuryQ60609564
Pulmonary recruitment, adherence, and chemotaxis of neutrophils in a rat model of cirrhosis and pneumococcal pneumoniaQ68064107
Identification of a panel of five serum miRNAs as a biomarker for Parkinson's diseaseQ86847853
Next generation sequencing reveals microRNA isoforms in liver cirrhosis and hepatocellular carcinomaQ87980389
Insulin signalling and the regulation of glucose and lipid metabolismQ24292020
MicroRNAs: target recognition and regulatory functionsQ24609584
Circulating microRNAs, potential biomarkers for drug-induced liver injuryQ24656209
Inhibition of Alpha Interferon Signaling by Hepatitis B VirusQ27478029
Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potentialQ28077959
A pancreatic islet-specific microRNA regulates insulin secretionQ28292726
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Q29547403
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteinsQ29615034
Characterization of microRNA expression profiles in normal human tissuesQ29615492
Mechanisms of fibrogenesis in liver cirrhosis: The molecular aspects of epithelial-mesenchymal transitionQ33563882
Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitisQ34082773
Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studiesQ34291952
Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAsQ34305941
miRBase: the microRNA sequence databaseQ34564134
Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2.Q34951363
IsomiRage: From Functional Classification to Differential Expression of miRNA IsoformsQ35343481
Application of high-throughput sequencing to circulating microRNAs reveals novel biomarkers for drug-induced liver injuryQ35379600
A liver-specific microRNA binds to a highly conserved RNA sequence of hepatitis B virus and negatively regulates viral gene expression and replication.Q35609609
GenSensor Suite: A Web-Based Tool for the Analysis of Gene and Protein Interactions, Pathways, and RegulationQ35614928
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal cladesQ35633577
What is normal? Next generation sequencing-driven analysis of the human circulating miRNAOmeQ35918523
Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in childrenQ36022680
MicroRNAs in body fluids--the mix of hormones and biomarkersQ36176435
Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury.Q36187981
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesDESeq2Q113018293
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
pathogenesisQ372016
biopsyQ179991
hepatotoxicityQ1349821
P304page(s)e0177928
P577publication date2017-05-17
P1433published inPLOS OneQ564954
P1476titleSerum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human
P478volume12

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cites work (P2860)
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Q64068390Diffusion-weighted magnetic resonance imaging and micro-RNA in the diagnosis of hepatic fibrosis in chronic hepatitis C virus
Q92651928Direct Detection of miR-122 in Hepatotoxicity Using Dynamic Chemical Labeling Overcomes Stability and isomiR Challenges
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Q90963083Latest advances in diagnosing and predicting DILI: what was new in 2017?
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Q47947610MicroRNAs as biomarkers for clinical studies
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Q60961914The diagnostic role of miR-122 in drug-induced liver injury: A systematic review and meta-analysis
Q50053201The human circulating miRNome reflects multiple organ disease risks in association with short-term exposure to traffic-related air pollution

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