CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy.

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CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0178352
P932PMC publication ID5446182
P698PubMed publication ID28552941

P50authorJinping ZhangQ88171818
P2093author name stringYuan Li
Lei Shen
Qing Qiao
Xiaopan Zhang
Guoyuan Lu
Jieqiong Sun
P2860cites work[Intercapillary deposits of IgA-IgG]Q54576467
Recruitment of CCR6-expressing Th17 cells by CCL 20 secreted from IL-1 beta-, TNF-alpha-, and IL-17A-stimulated endometriotic stromal cells.Q54646957
Interaction of IgA with Fc alpha receptors of human mesangial cells activates transcription factor nuclear factor-kappa B and induces expression and synthesis of monocyte chemoattractant protein-1, IL-8, and IFN-inducible protein 10Q73748087
IgA nephropathyQ74735791
Polymeric IgA increases the synthesis of macrophage migration inhibitory factor by human mesangial cells in IgA nephropathyQ78655918
IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cellsQ81324718
IgA nephropathyQ81805629
Chemokines play a critical role in the cross-regulation of Th1 and Th17 immune responses in murine crescentic glomerulonephritisQ83863964
IL-17A produced by both γδ T and Th17 cells promotes renal fibrosis via RANTES-mediated leukocyte infiltration after renal obstructionQ87662585
IL-17 and Th17 CellsQ27860566
Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARCQ28239561
Interleukin-17 and type 17 helper T cellsQ28256510
Differentiation of effector CD4 T cell populations (*)Q29614838
The CC chemokine CCL20 and its receptor CCR6.Q30333360
The role of Th1 and Th17 cells in glomerulonephritisQ30487944
Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitisQ31156447
Chemokines, chemokine receptors, and renal disease: from basic science to pathophysiologic and therapeutic studiesQ33806880
Chemokine receptor expression by inflammatory T cells in EAE.Q33846596
CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritisQ33979326
Hemolytic Streptococcus may exacerbate kidney damage in IgA nephropathy through CCL20 response to the effect of Th17 cellsQ34275117
CCL20 Secretion from the Nucleus Pulposus Improves the Recruitment of CCR6-Expressing Th17 Cells to Degenerated IVD TissuesQ34792558
Synergistic effect of mesangial cell-induced CXCL1 and TGF-β1 in promoting podocyte loss in IgA nephropathyQ34983730
The role of chemokines and chemokine receptors in progressive renal diseases.Q35075856
Chemokines and chemokine receptors are involved in the resolution or progression of renal disease.Q35083615
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.Q36229199
Kidney diseases and chemokinesQ36384807
CC Chemokine Ligand 20 and Its Cognate Receptor CCR6 in Mucosal T Cell Immunology and Inflammatory Bowel Disease: Odd Couple or Axis of Evil?Q37012341
Chemokines and leukocyte trafficQ37246677
The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathyQ37525267
The Th17 immune response in renal inflammationQ37726972
Macromolecular IgA1 taken from patients with familial IgA nephropathy or their asymptomatic relatives have higher reactivity to mesangial cells in vitroQ38355363
Targeting IL-17 and IL-23 in Immune Mediated Renal DiseaseQ38621612
Glycosylation of circulating IgA in patients with IgA nephropathy modulates proliferation and apoptosis of mesangial cells.Q43717108
Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin systemQ44669207
Human T cells that are able to produce IL-17 express the chemokine receptor CCR6.Q45054355
CCR6/CCL20 chemokine expression profile in distinct colorectal malignanciesQ45088749
IgA nephropathy: a disease in search of a large-scale clinical trial to reliably inform practiceQ46187159
Synthesis of TNF-alpha by mesangial cells cultured with polymeric anionic IgA--role of MAPK and NF-kappaB.Q46980113
Soluble IgA and IgG aggregates are catabolized by cultured rat mesangial cells and induce production of TNF-alpha and IL-6, and proliferation.Q50767056
Regulation of IL-17 in human CCR6+ effector memory T cells.Q51964294
Interleukin-17 induces CC chemokine receptor 6 expression and cell migration in colorectal cancer cells.Q53021850
TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis.Q53510500
Expression of the chemokine receptor CCR6 in human renal inflammation.Q54411230
Spleen tyrosine kinase is important in the production of proinflammatory cytokines and cell proliferation in human mesangial cells following stimulation with IgA1 isolated from IgA nephropathy patients.Q54485643
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmesangial cellQ3331086
P304page(s)e0178352
P577publication date2017-05-26
P1433published inPLOS OneQ564954
P1476titleCCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy
P478volume12

Reverse relations

cites work (P2860)
Q64082489Hirudin ameliorates immunoglobulin A nephropathy by inhibition of fibrosis and inflammatory response
Q93222504IL-17 in Renal Immunity and Autoimmunity
Q91976174Mesangial Cells Exhibit Features of Antigen-Presenting Cells and Activate CD4+ T Cell Responses
Q58593956T cells in IgA nephropathy: role in pathogenesis, clinical significance and potential therapeutic target
Q91714381The Role of Immune Modulation in Pathogenesis of IgA Nephropathy

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