| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1980PNAS...77.4354D |
| P356 | DOI | 10.1073/PNAS.77.7.4354 |
| P932 | PMC publication ID | 349833 |
| P698 | PubMed publication ID | 6933488 |
| P5875 | ResearchGate publication ID | 16264521 |
| P50 | author | Elias James Corey | Q135171 |
| P2093 | author name string | R A Lewis | |
| J M Drazen | |||
| K F Austen | |||
| A Marfat | |||
| D A Clark | |||
| G Goto | |||
| P2860 | cites work | The release of histamine and formation of a slow-reacting substance (SRS-A) during anaphylactic shock | Q24537753 |
| Some quantitative uses of drug antagonists | Q29616831 | ||
| Leukotriene C: a slow-reacting substance from murine mastocytoma cells | Q33972104 | ||
| Effects of Intravenous Administration of Slow-Reacting Substance of Anaphylaxis, Histamine, Bradykinin, and Prostaglandin F2α on Pulmonary Mechanics in the Guinea Pig | Q34519374 | ||
| Slow reacting substances of anaphylaxis: Identification of leukotrienes C-1 and D from human and rat sources | Q36395340 | ||
| Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guinea pig tracheal spirals and parenchymal strips | Q37034601 | ||
| Structure of leukotriene C identification of the amino acid part | Q39296258 | ||
| Bronchodilator activity of dimaprit in the guinea pig in vitro and in vivo | Q39887408 | ||
| Lung mechanics following antigen challenge of Ascaris suum-sensitive rhesus monkeys | Q44698740 | ||
| Selective inhibitor of slow reacting substance of anaphylaxis. | Q54018062 | ||
| Pulmonary response to antigen infusion in the sensitized guinea pig: modification by atropine | Q67367611 | ||
| Occurrence of an unidentified substance during anaphylactic shock in cavy lung | Q73184860 | ||
| Mechanics of respiration in unanesthetized guinea pigs | Q74804934 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4354-4358 | |
| P577 | publication date | 1980-07-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro | |
| P478 | volume | 77 |
| Q44563484 | 5-lipoxygenase knockout mice exhibit a resistance to acute pancreatitis induced by cerulein |
| Q43790347 | A Tale of Two CysLTs |
| Q36973737 | A novel clade of cysteinyl leukotriene scavengers in soft ticks. |
| Q69839498 | A possible role for leukotrienes in the regulation of glomerular haemodynamics in the dog |
| Q41273463 | A specific LTD4/LTE4-receptor antagonist improves pulmonary function in patients with mild, chronic asthma |
| Q44264978 | Actions of cysteinyl leukotrienes in the enteric nervous system of guinea-pig stomach and small intestine |
| Q43791880 | Acute effects of the cys-leukotriene-1 receptor antagonist, montelukast, on experimental colitis in rats |
| Q42538650 | Agonist and antagonist activities of the leukotriene analogue BAY u9773 in guinea pig lung parenchyma |
| Q37606896 | Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4 |
| Q70431958 | Alteration of leukotriene D4 hypotension by thyrotropin releasing hormone |
| Q36952174 | An eicosanoid-centric view of atherothrombotic risk factors |
| Q42635224 | An in vivo model for measuring antigen-induced SRS-A-mediated bronchoconstriction and plasma SRS-A levels in the guinea-pig |
| Q69008582 | Antagonism of the in vivo and in vitro effects of leukotriene D4 by SC-39070 in guinea pigs |
| Q54041134 | Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes. |
| Q34774360 | Anti-allergic therapies: effects on eosinophil progenitors. |
| Q41270730 | Anti-leukotriene agents: a new direction in asthma therapy |
| Q33930448 | Anti-leukotrienes in asthma: yet to arrive |
| Q40143304 | Arachidonic Acid Metabolism and Inflammation a brief Introduction |
| Q33595339 | Asthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs. |
| Q54312688 | Asthmatic airways have a disproportionate hyperresponsiveness to LTE4, as compared with normal airways, but not to LTC4, LTD4, methacholine, and histamine. |
| Q39495430 | Autonomic pharmacology of leukotrienes |
| Q46921890 | Biochemical and pharmacological characterization of the binding of the selective peptide-leukotriene antagonist, 3H-ICI 198,615, to leukotriene D4 receptors in guinea-pig lung membranes |
| Q70298182 | Bronchoconstrictor effects of leukotriene C in humans |
| Q42215096 | CSF leukotriene C4 following subarachnoid hemorrhage |
| Q70140218 | Calcium ionophore and chemotactic peptide stimulation of peptidoleukotriene synthesis in DMSO-differentiated HL60 cells |
| Q72909166 | Cellular regulatory role of leukotriene B4: Its effects on cation homeostasis in rabbit neutrophils |
| Q37506875 | Characterization of a leukotriene D4 receptor in guinea pig lung |
| Q72403879 | Characterization of specific receptors for leukotriene D4 on human alveolar macrophages |
| Q64074581 | Chemical Equilibrium at the Tick-Host Feeding Interface:A Critical Examination of Biological Relevance in Hematophagous Behavior |
| Q53473787 | Chemical Mediators of Immediate Hypersensitivity Reactions |
| Q41610803 | Childhood asthma and allergic rhinitis: the role of leukotrienes |
| Q36138245 | Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects |
| Q54424060 | Comparative role of peptide leukotrienes and histamine in the development of nasal mucosal swelling in nasal allergy. |
| Q41452031 | Concepts regarding formation, action, and pharmacologic inhibition of arachidonic acid metabolites in asthma |
| Q35367314 | Contractile activities of structural analogs of leukotrienes C and D: necessity of a hydrophobic region |
| Q35409446 | Contractile activities of structural analogs of leukotrienes C and D: role of the polar substituents |
| Q46191153 | Contraction of guinea pig gail bladder strips by leukotrienes and other agonists |
| Q24545573 | Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes |
| Q34181970 | Current treatment of asthma--focus on leukotrienes |
| Q42139167 | Cyclooxygenase blockade elevates leukotriene E4 production during acute anaphylaxis in sheep |
| Q28536784 | CysLT(1)R antagonists inhibit tumor growth in a xenograft model of colon cancer |
| Q40852202 | Cysteinyl leukotriene 1 receptor influences intestinal polyp incidence in a gender-specific manner in the ApcMin/+ mouse model |
| Q24633568 | Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes |
| Q28308101 | Cysteinyl leukotrienes and their receptors: bridging inflammation and colorectal cancer |
| Q30310359 | Cysteinyl leukotrienes in chronic hyperplastic rhinosinusitis |
| Q43819143 | Design, synthesis and pharmacological evaluation of novel pyrazolo[3,4-b]thieno[2,3-d]pyridine acid derivatives: a new class of anti-inflammatory and anti-platelet agents |
| Q72886780 | Detection of leukotriene A4 as an intermediate in the biosynthesis of leukotrienes C4 and D4 |
| Q70489397 | Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations |
| Q34293766 | Discovery of leukotrienes and development of antileukotriene agents |
| Q36568292 | Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis |
| Q44730447 | Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats |
| Q35871386 | Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on PAF-induced airway responses in neonatally immunized rabbits |
| Q69812346 | Effect of arachidonic acid, fatty acids, prostaglandins, and leukotrienes on volume regulation in Ehrlich ascites tumor cells |
| Q36180930 | Effect of azelastine on bronchoconstriction induced by histamine and leukotriene C4 in patients with extrinsic asthma |
| Q54057196 | Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects. |
| Q44794382 | Effect of sulfidopeptide leukotriene receptor antagonists on endotoxin-induced pulmonary dysfunction in awake sheep |
| Q36573372 | Effect of the 5-lipoxygenase inhibitor ZD2138 on allergen-induced early and late asthmatic responses |
| Q36573399 | Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma |
| Q72555247 | Effect of the Ca2+ antagonist nifedipine on the release of platelet-activating factor (PAF-acether), slow-reacting substance and β-glucuronidase from human neutrophils |
| Q35532086 | Effect of the leukotriene receptor antagonist pranlukast on cellular infiltration in the bronchial mucosa of patients with asthma |
| Q41249700 | Effects of L-serine borate on antagonism of leukotriene C4-induced contractions of guinea-pig trachea |
| Q34403416 | Effects of leukotrienes C4 and D4 on human isolated saphenous veins |
| Q35562984 | Effects of the neuroimmune mediators, peptidoleukotrienes, endothelin, and interleukin-1 on intestinal ion transport |
| Q40457625 | Eicosanoids and asthma: an update |
| Q40818931 | Eicosanoids and phospholipases |
| Q38487485 | Endogenous regulation of bronchomotor tone |
| Q54429198 | Evaluation of LY163443, 1-[2-hydroxy-3-propyl-4-([4- (1H-tetrazol-5-ylmethyl)phenoxy]methyl) phenyl]ethanone, as a pharmacologic antagonist of leukotrienes D4 and E4. |
| Q42577082 | Experimental model of ischemic bowel necrosis. The role of platelet-activating factor and endotoxin |
| Q67298623 | Heterogeneity of leukotriene receptions in guinea-pig trachea |
| Q72688292 | Human epidermis transforms exogenous leukotriene A4 into peptide leukotrienes: possible role in transcellular metabolism |
| Q25256827 | Hyperresponsiveness to inhaled but not intravenous methacholine during acute respiratory syncytial virus infection in mice |
| Q68462301 | Hypoxia and CCl4-induced liver injury, but not acidosis, impair metabolism of cysteinyl leukotrienes in perfused rat liver |
| Q40380559 | Identification and characterization of a monocyte-derived neutrophil-activating factor in corticosteroid-resistant bronchial asthma |
| Q44269714 | Identification and characterization of leukotriene C4 receptors in isolated rat renal glomeruli. |
| Q72526877 | IgE-dependent release of leukotriene C4 from alveolar macrophages |
| Q46886073 | Immunological and non-immunological release of leukotrienes and histamine by guinea-pig heart. |
| Q47793566 | In vitro antigen-specific sulphidoleukotriene production in patients allergic to Dermatophagoides pteronyssinus. |
| Q74593919 | In vitro responses to antigen stimulation: comparison between human lung parenchyma resected from asthmatic patients and non-asthmatic patients |
| Q72919064 | In vivo effects of leukotriene B4, C4 and D4. Evidence that changes in blood pressure are mediated by prostaglandins |
| Q44198490 | Increased leukotrienes in exhaled breath condensate in childhood asthma |
| Q69892333 | Inflammatory mechanisms in the Arthus reaction |
| Q41864703 | Influence of epithelium on the inhibition of melittin-induced contraction of guinea-pig isolated trachea by the potassium channel opener NIP-121. |
| Q53919262 | Interaction of leukotriene D4 and histamine on bronchomotor tone, in the guinea-pig. |
| Q37054017 | Interactions Between Macrophages and Granulocytes in Bronchial Asthma |
| Q46803385 | Involvement of capsaicin-sensitive afferent neurones in a vagal-dependent interaction between leukotriene D4 and histamine on bronchomotor tone |
| Q39640198 | Late-phase IgE-mediated reactions |
| Q42604168 | Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha |
| Q67868849 | Leukotriene A4 modulates generation of leukotriene B4 and sulphidopeptide leukotrienes by human neutrophils |
| Q36267105 | Leukotriene B4 action on endothelium mediates augmented neutrophil/endothelial adhesion |
| Q59054282 | Leukotriene C4 affects pulmonary and cardiovascular dynamics in monkey |
| Q68743794 | Leukotriene C4 and D4 contract rat glomerular mesangial cells |
| Q41581363 | Leukotriene D4 potentiates histamine-induced bronchoconstriction in guinea-pigs. |
| Q37562061 | Leukotriene E4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfidopeptide leukotriene receptors |
| Q36882130 | Leukotriene antagonists and inhibitors of leukotriene biosynthesis as potential therapeutic agents |
| Q36346186 | Leukotriene generation by eosinophils |
| Q36205826 | Leukotriene modifiers as potential therapeutics for cardiovascular disease |
| Q37810108 | Leukotriene pathway in sickle cell disease: a potential target for directed therapy |
| Q35779312 | Leukotriene receptor antagonists--risks and benefits for use in paediatric asthma |
| Q33705498 | Leukotriene receptors |
| Q59821954 | Leukotriene receptors as potential therapeutic targets |
| Q40842366 | Leukotriene-receptor antagonists and 5-lipoxygenase inhibitors in asthma |
| Q46870989 | Leukotrienes C and D induce aspirin-sensitive bronchoconstriction in the guinea-pig |
| Q55982487 | Leukotrienes and Inflammation |
| Q39144237 | Leukotrienes and airway responses. |
| Q24563001 | Leukotrienes and aspirin induced asthma |
| Q40087798 | Leukotrienes and lung disease |
| Q53922282 | Leukotrienes as mediators of skin inflammation |
| Q49314573 | Leukotrienes in disease. Implications for drug development |
| Q24634918 | Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response |
| Q40133100 | Leukotrienes, allergy and inflammation |
| Q40132150 | Leukotrienes: A Novel Group of Biologically Active Compounds |
| Q40268064 | Leukotrienes: a new approach to the biochemistry of hypersensitivity. |
| Q39521976 | Leukotrienes: regulation of biosynthesis, metabolism, and bioactivity |
| Q37061552 | Leukotrienes: their possible role in pulpal and periapical diseases |
| Q72085346 | Lung responsiveness to antigen in sensitised mice of different strains |
| Q40955961 | Management of asthma with zafirlukast. Clinical experience and tolerability profile |
| Q39399589 | Mast cells in allergic diseases and mastocytosis |
| Q46159151 | Mechanisms of leukotriene-induced contractions of guinea pig airways: Leukotriene C4has a potent direct action whereas leukotriene B4acts indirectly |
| Q40084813 | Mediation of local homeostasis and inflammation by leukotrienes and other mast cell-dependent compounds |
| Q40108738 | Mediators of Anaphylaxis |
| Q72863354 | Mediators of Immediate Hypersensitivity Derived from Arachidonic Acid |
| Q41748208 | Mediators of arachidonic acid-induced contractions of indomethacin-treated guinea-pig airways: leukotrienes C4 and D4. |
| Q38221901 | Metabolic interactions between eicosanoids in blood and vascular cells |
| Q40109738 | Metabolites of arachidonic acid |
| Q72390113 | Molecular determinants for functional responses to the sulfidopeptide leukotrienes: Metabolism and receptor subclasses |
| Q70340074 | Monocytes activate eosinophils for enhanced helminthotoxicity and increased generation of leukotriene C4 |
| Q57638511 | Nebulization and selective deposition of LTD4in human lungs |
| Q34443036 | Neurally mediated airway constriction in human and other species: a comparative study using precision-cut lung slices (PCLS). |
| Q39742728 | New developments concerning leukotriene antagonists: a review |
| Q46950553 | Nicardipine suppresses bronchoconstrictor actions of pharmacologic agents in guinea pigs |
| Q36344497 | Novel structural determinants of the human neutrophil chemotactic activity of leukotriene B. |
| Q40261836 | Oxygenation products of arachidonic acid as mediators of hypersensitivity and inflammation |
| Q41898865 | Pathogenic Mechanisms and In Vitro Diagnosis of AERD. |
| Q70214964 | Peptide Leukotriene Release after Antigen Challenge in Patients Sensitive to Ragweed |
| Q50532820 | Peptide leukotriene receptor antagonist diminishes pancreatic edema formation in rats with cerulein-induced acute pancreatitis. |
| Q46456215 | Pharmacological activity of leukotrienes A4, B4, C4 and D4 on selected guinea-pig, rat, rabbit and human smooth muscles |
| Q46569184 | Pharmacological alteration of antigen-induced contraction of lung parenchymal strips isolated from the actively sensitized guinea pig |
| Q33836701 | Pharmacological characterization of leukotriene receptors |
| Q35044822 | Pharmacological evidence for a novel cysteinyl-leukotriene receptor subtype in human pulmonary artery smooth muscle |
| Q46288179 | Pharmacological study of the effects of leukotrienes C4, D4, E4 & F4 on guinea pig trachelis: Interaction with FPL-55712 |
| Q37518954 | Pharmacology of peptide leukotriene receptor antagonists |
| Q33805187 | Pharmacotherapy of asthma in children, with special reference to leukotriene receptor antagonists |
| Q90623550 | Phase 2 trial of montelukast for prevention of pain in sickle cell disease |
| Q46984900 | Platelet-activating factor-induced contraction of guinea-pig lung parenchymal strips: possible involvement of arachidonate metabolites |
| Q42939963 | Prevention of endogenous leukotriene production during anaphylaxis in the guinea pig by an inhibitor of leukotriene biosynthesis (MK-886) but not by dexamethasone |
| Q70050119 | Production of peptide leukotrienes in endotoxin shock |
| Q35586687 | Properties of highly purified leukotriene C4 synthase of guinea pig lung |
| Q36097894 | Propranolol-induced airway hyperreactivity in guinea-pigs |
| Q40150237 | Prostaglandin and Thromboxane Mediation of Cardiopulmonary Failure |
| Q34192889 | Prostaglandins, thromboxanes and leukotrienes in clinical medicine |
| Q69816137 | Recombinant human tumour necrosis factor (rTNF)2 enhances leukotriene biosynthesis in neutrophils and eosinophils stimulated with the Ca2+ ionophore A23187 |
| Q33705470 | Regulation of expression of the 5-lipoxygenase pathway |
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| Q68259501 | Release of leukotriene C4 in respiratory tract during acute viral infection |
| Q43506240 | Release of leukotrienes and histamine by the isolated anaphylactic heart |
| Q46231942 | Release of slow reacting substance from the guinea-pig lung by phospholipases A2 of Vipera russelli snake venom |
| Q71350693 | Renal and systemic hemodynamic responses to intravenous infusion of leukotriene C4 in the rat |
| Q42049963 | Renal vascular effects of leukotriene C4 in the isolated perfused kidney of the rat. |
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