A mimic of phosphorylated prolactin induces apoptosis by activating AP-1 and upregulating p21/waf1 in human prostate cancer PC3 cells

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A mimic of phosphorylated prolactin induces apoptosis by activating AP-1 and upregulating p21/waf1 in human prostate cancer PC3 cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OL.2012.876
P932PMC publication ID3499593
P698PubMed publication ID23162652
P5875ResearchGate publication ID233539840

P2093author name stringWei Wu
Lianlian DU
P2860cites workA short form of the prolactin (PRL) receptor is able to rescue mammopoiesis in heterozygous PRL receptor miceQ44353904
Different biological effects of unmodified prolactin and a molecular mimic of phosphorylated prolactin involve different signaling pathways.Q44479705
Ligand-independent homo- and heterodimerization of human prolactin receptor variants: inhibitory action of the short forms by heterodimerization.Q50735815
Prolactin (PRL)-PRL receptor system increases cell proliferation involving JNK (c-Jun amino terminal kinase) and AP-1 activation: inhibition by glucocorticoidsQ73688138
Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelopeQ36972637
TNF-alpha/IL-1/NF-kappaB transduction pathway in human cancer prostateQ37246961
Prolactin and prolactin receptors are expressed and functioning in human prostateQ37363252
Naringin-induced p21WAF1-mediated G(1)-phase cell cycle arrest via activation of the Ras/Raf/ERK signaling pathway in vascular smooth muscle cellsQ38498234
Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kappaB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase.Q38504930
Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylationQ39923869
S179D prolactin sensitizes human prostate cancer cells such that physiological concentrations of 1, 25 dihydroxy vitamin D3 result in growth inhibition and cell deathQ40097694
Different forms of prolactin have opposing effects on the expression of cell cycle regulatory proteins in differentiated mammary epithelial cells.Q40245543
S179D prolactin increases vitamin D receptor and p21 through up-regulation of short 1b prolactin receptor in human prostate cancer cellsQ40384675
Human prolactin receptor variants in breast cancer: low ratio of short forms to the long-form human prolactin receptor associated with mammary carcinomaQ40525069
A molecular mimic of phosphorylated prolactin markedly reduced tumor incidence and size when DU145 human prostate cancer cells were grown in nude mice.Q40785892
Prolactin stimulates activation of c-jun N-terminal kinase (JNK).Q40847193
Transduction of prolactin's (PRL) growth signal through both long and short forms of the PRL receptorQ42819754
P433issue5
P921main subjectphosphorylationQ242736
P304page(s)1064-1068
P577publication date2012-08-23
P1433published inOncology LettersQ20640514
P1476titleA mimic of phosphorylated prolactin induces apoptosis by activating AP-1 and upregulating p21/waf1 in human prostate cancer PC3 cells
P478volume4

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