scholarly article | Q13442814 |
P819 | ADS bibcode | 1980PNAS...77.5663F |
P356 | DOI | 10.1073/PNAS.77.10.5663 |
P953 | full work available at URL | https://europepmc.org/articles/PMC350129 |
https://europepmc.org/articles/PMC350129?pdf=render | ||
https://pnas.org/doi/pdf/10.1073/pnas.77.10.5663 | ||
P932 | PMC publication ID | 350129 |
P698 | PubMed publication ID | 6160578 |
P5875 | ResearchGate publication ID | 17024905 |
P2093 | author name string | J. R. Bertino | |
D. J. Fernandes | |||
P2860 | cites work | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 |
Inhibition of thymidylate synthetase and dihydrofolate reductase by naturally occurring oligoglutamate derivatives of folic acid | Q28336731 | ||
Cytotoxicity of 5-fluoro-2'-deoxyuridine: requirement for reduced folate cofactors and antagonism by methotrexate | Q33963638 | ||
Role of thymidylate synthetase activity in development of methotrexate cytotoxicity | Q33982869 | ||
Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion | Q34484419 | ||
Assay of intracellular free and macromolecular-bound metabolites of 5-fluorodeoxyuridine and 5-fluorouracil | Q39892733 | ||
Human thymidylate synthetase derived from blast cells of patients with acture myelocytic leukemia. Purification and chracterization | Q40505167 | ||
Schedule-dependent antitumor effects of methotrexate and 5-fluorouracil | Q41050779 | ||
Formation of methotrexate polyglutamates in rat hepatocytes | Q41673315 | ||
Enhanced 5-Fluorouracil Nucleotide Formation After Methotrexate Administration: Explanation for Drug Synergism | Q41760435 | ||
Effect of [3H]methotrexate impurities on apparent transport of methotrexate by a sensitive and resistant L1210 cell line. | Q42261665 | ||
The interconversion of serine and glycine; preparation and properties of catalytic derivatives of pteroylglutamic acid | Q42954216 | ||
Accumulation of methotrexate diglutamate in human liver during methotrexate therapy | Q43805026 | ||
Studies with a mathematical model of folate metabolism | Q44050316 | ||
Therapeutic consequences of antitumour drug interactions: methotrexate and 5-fluorouracil in the chemotherapy of C3H mice with transplanted mammary adenocarcinoma | Q44527223 | ||
Polyglutamyl derivatives of folate as substrates and inhibitors of thymidylate synthetase. | Q44939984 | ||
The identification of pteroylpentaglutamate as the major folate derivative in rat liver and the demonstration of its biosynthesis from exogenous [3H] pteroylglutamate | Q45057225 | ||
Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides. | Q52163261 | ||
Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis | Q52859269 | ||
7,8-Dihydropteroyl oligo-γ-L-glutamates. Synthesis and kinetic studies with purified dihydrofolate reductase from mammalian sources | Q53782667 | ||
Polygammaglutamyl metabolites of methotrexate. | Q53801402 | ||
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The incorporation of 3H-cytosine arabinoside and its effect on murine leukemic cells (L5178Y) | Q54342224 | ||
Effects of 5-fluorouracil on 5-fluorodeoxyuridine 5'-monophosphate and 2-deoxyuridine 5'-monophosphate pools, and DNA synthesis in solid mouse L1210 and rat Walker 256 tumors | Q54582208 | ||
Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. | Q54642095 | ||
Purification of mammalian tumor (L1210) thymidylate synthetase by affinity chromatography on stable biospecific adsorbent. Stabilization of the enzyme with neutral detergents | Q66961523 | ||
Inhibition of pig liver methylenetetrahydrofolate reductase by dihydrofolate: some mechanistic and regulatory implications | Q66971081 | ||
The turnover of folate coenzymes in murine lymphoma cells | Q67254001 | ||
Synthesis of methotrexate polyglutamates in cultured human cells | Q67268196 | ||
Purification and properties of T2 bacteriophage-induced thymidylate synthetase | Q67291204 | ||
Human thymidylate synthetase. II. Derivatives of pteroylmono- and -polyglutamates as substrates and inhibitors | Q67327959 | ||
Demonstration of separate binding sites for the folate coenzymes and deoxynucleotides with inactivated Lactobacillus casei thymidylate synthetase | Q67526222 | ||
Folate metabolism in mammalian cells in culture. I Partial characterization of the folate derivatives present in L1210 mouse leukemia cells | Q67769087 | ||
Mechanism of action of methotrexate. IV. Free intracellular methotrexate required to suppress dihydrofolate reduction to tetrahydrofolate by Ehrlich ascites tumor cells in vitro | Q68287945 | ||
Formyltetrahydrofolate synthetase. Binding of adenosine triphosphate and related ligands determined by partition equilibrium | Q70618330 | ||
Separation of pteroyl-oligo-gamma-L-glutamates by high-performance liquid-chromatography | Q71192300 | ||
A New Assay of Thymidylate Synthetase Activity Based on the Release of Tritium from Deoxyuridylate-5-3H | Q71196962 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 5663-5667 | |
P577 | publication date | 1980-10-01 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | 5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates | |
P478 | volume | 77 |