Human mutL homolog 1 expression characteristic and prognostic effect on patients with sporadic colorectal cancer

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Human mutL homolog 1 expression characteristic and prognostic effect on patients with sporadic colorectal cancer is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4694529
P698PubMed publication ID26770629

P2093author name stringXiaoyan Wang
Wei Yuan
Shourong Shen
Xianbo Yu
Zhenqiang Sun
Chibin Pu
Mingyu Huang
Weiguo Ren
P2860cites workGlobal cancer statisticsQ22241238
Molecular origins of cancer: Molecular basis of colorectal cancerQ24617331
Mutation of a mutL homolog in hereditary colon cancerQ28114939
Promoter methylation status of DNA repair gene (hMLH1) in gastric carcinoma patients of the Kashmir valleyQ28277915
Systematic review of microsatellite instability and colorectal cancer prognosisQ28303189
Mismatch repair defects in cancerQ33885063
Microsatellite instability in colorectal adenomas: relevance and clinical importanceQ34047914
Is reduced expression of mismatch repair genes MLH1 and MSH2 in patients with sporadic colorectal cancer related to their prognosis?Q34579284
Are there two sides to colorectal cancer?Q34822109
Mismatch repair genes expression defects & association with clinicopathological characteristics in colorectal carcinomaQ35234577
The role of hypermethylation of the hMLH1 promoter region in HNPCC versus MSI+ sporadic colorectal cancersQ35435480
Molecular pathways: microsatellite instability in colorectal cancer: prognostic, predictive, and therapeutic implicationsQ35836592
HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differencesQ35875965
Extensive molecular screening for hereditary non-polyposis colorectal cancerQ36641429
Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian seriesQ36776983
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screeningQ37066133
Microsatellite instability and therapeutic consequences in colorectal cancer.Q38020733
Role of microsatellite instability in the management of colorectal cancersQ38063688
Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part I. The utility of immunohistochemistryQ39514722
Prognostic impact of microsatellite instability in colorectal cancer patients treated with adjuvant FOLFOX.Q42841501
Prognostic value of microsatellite instability in sporadic locally advanced rectal cancer following neoadjuvant radiotherapyQ45001727
Deficient mismatch repair phenotype is a prognostic factor for colorectal cancer in elderly patientsQ45768258
Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer.Q46121063
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instabilityQ47704165
Survival analysis in families affected by hereditary non-polyposis colorectal cancer.Q50957274
Microsatellite instability in sporadic colorectal carcinoma is not an indicator of prognosis.Q54129757
Better survival rates in patients with MLH1-associated hereditary colorectal cancerQ57567998
Immunohistochemical Test for MLH1 and MSH2 Expression Predicts Clinical Outcome in Stage II and III Colorectal Cancer PatientsQ60729686
Microsatellite instability in sporadic colon carcinomas has no independent prognostic value in a Belgian study populationQ62937143
Mutations in MLH1 are more frequent than in MSH2 in sporadic colorectal cancers with microsatellite instabilityQ71970804
Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancersQ74690591
Correlation of mismatch repair genes immunohistochemistry and microsatellite instability status in HNPCC-associated tumoursQ78852509
Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancerQ80557773
Value of immunohistochemical detection of DNA mismatch repair proteins in predicting germline mutation in hereditary colorectal neoplasmsQ81186123
Expression of the hMLH1 and hMSH2 proteins in normal tissues: relationship to cancer predisposition in hereditary non-polyposis colon cancerQ81450104
Mismatch repair status in sporadic colorectal cancer: immunohistochemistry and microsatellite instability analysesQ84202364
[Prognostic significance of macrosatellite instability in patients uder 50 years of age suffering from colorectal cancer]Q84339399
Absence of hMLH1 or hMSH2 expression as a stage-dependent prognostic factor in sporadic colorectal cancersQ84409187
[Influence of microsatellite instability on survival of patients with sporadic colorectal cancer in China]Q84598042
P433issue10
P921main subjectcolorectal cancerQ188874
P304page(s)19652-19661
P577publication date2015-10-15
P1433published inInternational Journal of Clinical and Experimental MedicineQ6051338
P1476titleHuman mutL homolog 1 expression characteristic and prognostic effect on patients with sporadic colorectal cancer
P478volume8

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cites work (P2860)
Q90247729A Hereditable Mutation of MSH2 Gene Associated with Lynch Syndrome in a Five Generation Chinese Family
Q90643328DNA methylation biomarkers in stool for early screening of colorectal cancer
Q58583909Prognostic Value of Mismatch Repair Genes for Patients With Colorectal Cancer: Meta-Analysis

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