Ablation of leptin signaling disrupts the establishment, development, and maintenance of endometriosis-like lesions in a murine model

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Ablation of leptin signaling disrupts the establishment, development, and maintenance of endometriosis-like lesions in a murine model is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1210/EN.2007-1225
P932PMC publication ID2219296
P698PubMed publication ID17962343
P5875ResearchGate publication ID5884224

P2093author name stringBo R Rueda
Mark Puder
Takehiro Serikawa
Aaron K Styer
Tayyaba Hasan
Brian T Sullivan
John C Petrozza
Sung Chang
Danielle Arsenault
Ruben R Gonzalez
P2860cites workEndoglin (cd105) and S100A13 as markers of active angiogenesis in endometriosisQ24299810
The unfolding tale of PECAM-1Q28189310
Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)Q28586465
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppressionQ28594263
Whole explants of peritoneum and endometrium: a novel model of the early endometriosis lesionQ31915243
Histone H3.3 is enriched in covalent modifications associated with active chromatinQ33196967
Women with endometriosis show a defect in natural killer activity resulting in a decreased cytotoxicity to autologous endometriumQ33640412
Loss of cables, a cyclin-dependent kinase regulatory protein, is associated with the development of endometrial hyperplasia and endometrial cancerQ34290582
Aromatase and endometriosisQ34313406
'Green mice' as a source of ubiquitous green cells.Q34428099
Etanercept. ImmunexQ34562724
Experimental endometriosis: the nude mouse as a xenographic hostQ34597420
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Mechanisms of excessive estrogen formation in endometriosisQ34683491
Uterine chemokines in reproductive physiology and pathologyQ34690685
Endometriosis: novel etiopathogenetic concepts and clinical perspectives.Q34953089
Role of peritoneal inflammation in endometriosis-associated infertilityQ37773926
Leptin and leptin receptor are expressed in the human endometrium and endometrial leptin secretion is regulated by the human blastocystQ38305376
Biological action of leptin as an angiogenic factorQ38333557
Leptin serves as an upstream activator of an obligatory signaling cascade in the embryo-implantation processQ38334394
Leptin stimulates ischemia-induced retinal neovascularization: possible role of vascular endothelial growth factor expressed in retinal endothelial cellsQ38337328
Leptin-induced increase in leukemia inhibitory factor and its receptor by human endometrium is partially mediated by interleukin 1 receptor signalingQ38341191
Leptin regulation of the interleukin-1 system in human endometrial cellsQ38357235
Evidence for the risk of pelvic endometriosis by age, race and socioeconomic statusQ40189701
Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migrationQ40739492
Chemokine bioactivity of RANTES in endometriotic and normal endometrial stromal cells and peritoneal fluidQ40830304
A Reproductive Endocrine Profile in the Diabetes (db) Mutant Mouse1Q41061873
Increased leptin levels in serum and peritoneal fluid of patients with pelvic endometriosis.Q43586261
Effects of leptin, interleukin-1alpha, interleukin-6, and transforming growth factor-beta on markers of trophoblast invasive phenotype: integrins and metalloproteinasesQ43807132
Interleukin-8 as a macrophage-derived mediator of angiogenesisQ44053300
In vivo rat model of preeclampsiaQ44271036
Steroid receptor and aromatase expression in baboon endometriotic lesionsQ44593824
Endometriosis-associated ovarian carcinoma: differential expression of vascular endothelial growth factor and estrogen/progesterone receptorsQ44611371
Quantitative assessment of human endometriotic tissue maintenance and regression in a noninvasive mouse model of endometriosisQ44848772
Human endometriotic xenografts in immunodeficient RAG-2/gamma(c)KO miceQ45000779
Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis.Q46036918
Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosisQ46058843
Interleukin-8 concentrations are elevated in peritoneal fluid of women with endometriosisQ46721568
Neutrophils and macrophages promote angiogenesis in the early stage of endometriosis in a mouse modelQ46818333
A peptide derived from the human leptin molecule is a potent inhibitor of the leptin receptor function in rabbit endometrial cellsQ50337016
EndometriosisQ55951108
EndometriosisQ56627435
Delay in the diagnosis of endometriosis: a survey of women from the USA and the UKQ71162292
Transplantation of normal and ectopic human endometrial tissue into athymic nude miceQ71415339
Endometriosis: Associations with Menorrhagia, Infertility and Oral ContraceptivesQ72431782
Pathogenesis of endometriosisQ73279940
Inverse correlation between peritoneal fluid leptin concentrations and the extent of endometriosisQ73449770
Leptin and reproductionQ73940192
The peritoneal fluid concentration of leptin is increased in women with peritoneal but not ovarian endometriosisQ73959109
Increase in serum leptin concentrations among women with endometriosis during danazol and leuprolide depot treatmentsQ74090610
Leptin upregulates beta3-integrin expression and interleukin-1beta, upregulates leptin and leptin receptor expression in human endometrial epithelial cell culturesQ77582769
Time course of pelvic endometriotic lesion revascularization in a nude mouse modelQ81016649
Mechanism of elevated vascular endothelial growth factor levels in peritoneal fluids from patients with endometriosisQ81250110
Vascular endothelial growth factor A and C gene expression in endometriosisQ81314837
Angiostatic agents prevent the development of endometriosis-like lesions in the chicken chorioallantoic membraneQ81481765
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectendometriosisQ205764
murine modelQ122890741
P304page(s)506-514
P577publication date2007-10-25
P1433published inEndocrinologyQ3054009
P1476titleAblation of leptin signaling disrupts the establishment, development, and maintenance of endometriosis-like lesions in a murine model
P478volume149

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cites work (P2860)
Q34337117A novel role of the Sp/KLF transcription factor KLF11 in arresting progression of endometriosis
Q37729658Anti-Endometriotic Effects of Pueraria Flower Extract  in Human Endometriotic Cells and Mice
Q41958089Cardioprotective effect of notoginsenoside R1 in a rabbit lung remote ischemic postconditioning model via activation of the TGF-β1/TAK1 signaling pathway
Q47960296Early Endometriosis in Females Is Directed by Immune-Mediated Estrogen Receptor α and IL-6 Cross-Talk
Q37627341Ectopic endometrium-derived leptin produces estrogen-dependent chronic pain in a rat model of endometriosis
Q45416173Effects of leptin on lipopolysaccharide-induced remodeling in an in vitro model of human myometrial inflammation
Q90721057Elevated serum chemokines are independently associated with both endometriosis and uranium exposure
Q26750772Endometriosis: where are we and where are we going?
Q81898561Found in inflammatory zone 1 induces angiogenesis in murine models of asthma
Q36748684Gene expression of leptin and long leptin receptor isoform in endometriosis: a case-control study
Q33597069High-resolution ultrasound imaging: a novel technique for the noninvasive in vivo analysis of endometriotic lesion and cyst formation in small animal models
Q34506185Impact of surgical excision of lesions on pain in a rat model of endometriosis
Q37497913Increased expression of the leptin receptor in human ovaries affected by endometrioma and detection of high levels of leptin in the ovarian endometriomal fluid
Q36942357Intraperitoneal inflammation decreases endometriosis in a mouse model.
Q34577547Leptin pro-angiogenic signature in breast cancer is linked to IL-1 signalling
Q38855561Leptin promotes human endometriotic cell migration and invasion by up-regulating MMP-2 through the JAK2/STAT3 signaling pathway
Q33941240Leptin regulation of proangiogenic molecules in benign and cancerous endometrial cells
Q38151768Leptin-activity blockers: development and potential use in experimental biology and medicine
Q37277170Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer
Q41634189Niclosamide As a Potential Nonsteroidal Therapy for Endometriosis That Preserves Reproductive Function in an Experimental Mouse Model.
Q33952473Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer
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Q36114008Role of estrogen receptor signaling required for endometriosis-like lesion establishment in a mouse model
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Q33609029Transforming Growth Factor-beta 1 Involved in the Pathogenesis of Endometriosis through Regulating Expression of Vascular Endothelial Growth Factor under Hypoxia

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