| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1031299072 |
| P356 | DOI | 10.1186/S12974-015-0458-6 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1186/s12974-015-0458-6 |
| P932 | PMC publication ID | 4696218 |
| P698 | PubMed publication ID | 26714634 |
| P5875 | ResearchGate publication ID | 288918014 |
| P50 | author | Pietro Giusti | Q57075422 |
| P2093 | author name string | Maria Teresa Conconi | |
| Rosa Di Liddo | |||
| Thomas Bertalot | |||
| Laura Facci | |||
| Stephen D Skaper | |||
| Morena Zusso | |||
| Carla Marinelli | |||
| P2860 | cites work | Neuroinflammation and psychiatric illness | Q21245244 |
| MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4 | Q22009943 | ||
| Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs | Q24303416 | ||
| Toll-like receptors | Q27860671 | ||
| Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 | Q27860854 | ||
| The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors | Q27860900 | ||
| The role of neuroinflammation in neuropathic pain: mechanisms and therapeutic targets | Q28297385 | ||
| The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors | Q28512624 | ||
| Toll-like receptor 3 contributes to spinal glial activation and tactile allodynia after nerve injury | Q28567414 | ||
| Double-stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3-expressing astrocytes | Q28578265 | ||
| Microglia: active sensor and versatile effector cells in the normal and pathologic brain | Q29547240 | ||
| Negative regulation of toll-like receptor-mediated immune responses | Q29619019 | ||
| The immunology of stroke: from mechanisms to translation | Q29620066 | ||
| Astrocytes are active players in cerebral innate immunity | Q29620562 | ||
| Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity | Q30476891 | ||
| Microglial cells in astroglial cultures: a cautionary note | Q30480840 | ||
| The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy | Q30668465 | ||
| Comparative analysis of the effects of sample source and test methodology on the assessment of protein expression in acute myelogenous leukemia | Q33217703 | ||
| Applications of flow cytometry to clinical microbiology | Q33555394 | ||
| Signaling pathways involved in LPS induced TNFalpha production in human adipocytes | Q33645157 | ||
| Clinically useful information provided by the flow cytometric immunophenotyping of hematological malignancies: current status and future directions | Q33744603 | ||
| A Decade of Research on TLR2 Discovering Its Pivotal Role in Glial Activation and Neuroinflammation in Neurodegenerative Diseases | Q33787337 | ||
| Pathological pain and the neuroimmune interface | Q33925677 | ||
| Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS. | Q48716364 | ||
| Immunology. Dangers in and out. | Q51749187 | ||
| Reduction of TLR4 mRNA stability and protein expressions through inhibiting cytoplasmic translocation of HuR transcription factor by E₂ and/or ERα in LPS-treated H9c2 cardiomyoblast cells. | Q54369357 | ||
| In response to pathogens, glial cells dynamically and differentially regulate Toll-like receptor gene expression. | Q54644936 | ||
| TLR signaling tailors innate immune responses in human microglia and astrocytes | Q57041985 | ||
| Astrocytes enhance lipopolysaccharide-induced nitric oxide production by microglial cells | Q78445192 | ||
| Lipopolysaccharide regulates toll-like receptor 4 expression in human aortic smooth muscle cells | Q79895774 | ||
| Differential activation of astrocytes by innate and adaptive immune stimuli | Q80990228 | ||
| The role of TLR2 in nerve injury-induced neuropathic pain is essentially mediated through macrophages in peripheral inflammatory response | Q82705607 | ||
| Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways | Q82705613 | ||
| Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential | Q34510368 | ||
| Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ) | Q35124699 | ||
| Toll-like receptor expression and activation in astroglia: differential regulation by HIV-1 Tat, gp120, and morphine. | Q35779664 | ||
| Toll-like receptors in chronic pain | Q35830682 | ||
| Emerging role of Toll-like receptors in the control of pain and itch | Q35944972 | ||
| Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis | Q35945721 | ||
| Recognition of Staphylococcus aureus-derived peptidoglycan (PGN) but not intact bacteria is mediated by CD14 in microglia | Q36647941 | ||
| Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-gamma Agonists | Q36731548 | ||
| TLR2 expression in astrocytes is induced by TNF-alpha- and NF-kappa B-dependent pathways | Q37113924 | ||
| Toll-like receptors in neurodegeneration. | Q37186287 | ||
| A novel method to establish microglia-free astrocyte cultures: comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia | Q37418389 | ||
| Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice | Q37497125 | ||
| Toll-like receptors 2, -3 and -4 prime microglia but not astrocytes across central nervous system regions for ATP-dependent interleukin-1β release. | Q37738372 | ||
| Inflammation and neurodegeneration: the story 'retolled'. | Q38040234 | ||
| Toll-like receptors: sensor molecules for detecting damage to the nervous system | Q38084713 | ||
| Evolving Bacterial Envelopes and Plasticity of TLR2-Dependent Responses: Basic Research and Translational Opportunities | Q38160006 | ||
| Immune dysregulation in autism spectrum disorder | Q38168141 | ||
| Role of glia in neuropathic pain | Q38175748 | ||
| Microglial priming in neurodegenerative disease | Q38196699 | ||
| Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease | Q38203104 | ||
| Toll-like receptors in central nervous system injury and disease: a focus on the spinal cord | Q38234121 | ||
| The role of glia in the spinal cord in neuropathic and inflammatory pain | Q38407843 | ||
| Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt signaling pathways | Q39030143 | ||
| The procyanidin trimer C1 inhibits LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages | Q39222263 | ||
| Toll-like receptor signaling in amyotrophic lateral sclerosis spinal cord tissue | Q39785069 | ||
| MD-2 binds to bacterial lipopolysaccharide | Q40783908 | ||
| Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. | Q40870297 | ||
| The Extracellular IFI16 Protein Propagates Inflammation in Endothelial Cells Via p38 MAPK and NF-κB p65 Activation | Q41350185 | ||
| Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes | Q41889316 | ||
| Phenotype of the accessory cell necessary for mitogen-stimulated T and B cell responses in human peripheral blood: delineation by its sensitivity to the lysosomotropic agent, L-leucine methyl ester | Q41920471 | ||
| Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils. | Q44102020 | ||
| Innate and adaptive immune responses in neurodegeneration and repair. | Q44581205 | ||
| Myoloid-related protein 8, an endogenous ligand of Toll-like receptor 4, is involved in epileptogenesis of mesial temporal lobe epilepsy via activation of the nuclear factor-κB pathway in astrocytes | Q45084169 | ||
| Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response. | Q45098944 | ||
| Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells | Q45345615 | ||
| Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes | Q46654805 | ||
| A simplified flow cytometry method of CD4 and CD8 cell counting based on thermoresistant reagents: implications for large scale monitoring of HIV-infected patients in resource-limited settings | Q46721076 | ||
| Astrocyte-microglia cooperation in the expression of a pro-inflammatory phenotype | Q48088702 | ||
| Interferon-gamma reduces cyclooxygenase-2-mediated prostaglandin E2 production from primary mouse astrocytes independent of nitric oxide formation. | Q48181333 | ||
| Cultured astrocytes express toll-like receptors for bacterial products | Q48235492 | ||
| Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony | Q48337623 | ||
| Obtention and characterization of primary astrocyte and microglial cultures from adult monkey brains. | Q48626499 | ||
| Culture of neonatal rodent microglia, astrocytes, and oligodendrocytes from cortex and spinal cord. | Q48639546 | ||
| P921 | main subject | toll-like receptor | Q408004 |
| astrocyte | Q502961 | ||
| microglia | Q1622829 | ||
| P304 | page(s) | 244 | |
| P577 | publication date | 2015-12-30 | |
| P1433 | published in | Journal of Neuroinflammation | Q15716679 |
| P1476 | title | Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes | |
| P478 | volume | 12 |
| Q64137489 | A connexin43/YAP axis regulates astroglial-mesenchymal transition in hemoglobin induced astrocyte activation |
| Q64447018 | A core transcriptional signature of human microglia: Derivation and utility in describing region‐dependent alterations associated with Alzheimer's disease |
| Q58545225 | AST-120 Reduces Neuroinflammation Induced by Indoxyl Sulfate in Glial Cells |
| Q40531804 | Ammonia Attenuates LPS-Induced Upregulation of Pro-Inflammatory Cytokine mRNA in Co-Cultured Astrocytes and Microglia |
| Q41327539 | An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells |
| Q40260468 | Astrocyte-mediated inflammation in cortical spreading depression |
| Q61810725 | Bacterial regulation of macrophage bacterial recognition receptors in COPD are differentially modified by budesonide and fluticasone propionate |
| Q42367275 | CNS cell-type localization and LPS response of TLR signaling pathways |
| Q98223004 | Dichotomous engagement of HDAC3 activity governs inflammatory responses |
| Q64890712 | Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats. |
| Q42030450 | Expression and Differential Responsiveness of Central Nervous System Glial Cell Populations to the Acute Phase Protein Serum Amyloid A. |
| Q48510107 | Gene transfer of a naked plasmid (pUDK-HGF) encoding human hepatocyte growth factor attenuates skin/muscle incision and retraction-induced chronic post-surgical pain in rats. |
| Q64073224 | Glial phagocytic clearance in Parkinson's disease |
| Q46273850 | Hemoglobin pretreatment endows rat cortical astrocytes resistance to hemin-induced toxicity via Nrf2/HO-1 pathway |
| Q33785671 | Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia |
| Q42577077 | Inhibition of Zymosan-Induced Inflammatory Factors Expression by ATRA Nanostructured Lipid Carriers |
| Q88197849 | Juniperonic Acid Incorporation into the Phospholipids of Murine Macrophage Cells Modulates Pro-Inflammatory Mediator Production |
| Q38662525 | Lipopolysaccharide inhibits myogenic differentiation of C2C12 myoblasts through the Toll-like receptor 4-nuclear factor-κB signaling pathway and myoblast-derived tumor necrosis factor-α |
| Q33809556 | Microglial Activation in the Pathogenesis of Huntington's Disease |
| Q39401287 | Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival |
| Q42712047 | Pharmacological Tools to Activate Microglia and their Possible use to Study Neural Network Patho-physiology. |
| Q55505620 | Potential immunotherapies for traumatic brain and spinal cord injury. |
| Q38862845 | Regulation of striatal astrocytic receptor for advanced glycation end-products variants in an early stage of experimental Parkinson's disease |
| Q94481934 | Retinoic acid inducible gene-I mediated detection of bacterial nucleic acids in human microglial cells |
| Q47962378 | Role of pattern recognition receptors of the neurovascular unit in inflamm-aging. |
| Q55235067 | Serum amyloid A primes microglia for ATP-dependent interleukin-1β release. |
| Q38951157 | Sex Differences in Microglia Activity within the Periaqueductal Gray of the Rat: A Potential Mechanism Driving the Dimorphic Effects of Morphine. |
| Q97530906 | Synthesis, Characterization, and Biological Activity of Aminated Zymosan |
| Q52098231 | Systemic Inflammation as a Driver of Brain Injury: the Astrocyte as an Emerging Player. |
| Q40197681 | Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) Activation Balance Astrocyte Polarization into a Proinflammatory Phenotype. |
| Q61795497 | Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes |
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