A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen

scientific article

A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0092-8674(87)90148-6
P698PubMed publication ID2959371

P2093author name stringKeene JD
Query CC
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)211-220
P577publication date1987-10-01
P1433published inCellQ655814
P1476titleA human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen
P478volume51

Reverse relations

cites work (P2860)
Q24293251A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein
Q34253183A conserved idiotype and antibodies to retroviral proteins in systemic lupus erythematosus
Q47366034A general model for the evolution of nuclear pre-mRNA introns
Q43794971A murine cytomegalovirus-neutralizing monoclonal antibody exhibits autoreactivity and induces tissue damage in vivo.
Q71733572A new look at viruses in type 1 diabetes
Q35068487A new look at viruses in type 1 diabetes.
Q36795137A specific 31-nucleotide domain of U1 RNA directly interacts with the 70K small nuclear ribonucleoprotein component
Q36643316A subset of Pr65gag is nucleus associated in murine leukemia virus-infected cells
Q35134487Advances in B-cell epitope analysis of autoantigens in connective tissue diseases
Q70616885Alpha-enolase: a novel cytosolic autoantigen in ANCA positive vasculitis
Q84582675Altered posttranslational modification on U1 small nuclear ribonucleoprotein 68k in systemic autoimmune diseases detected by 2D Western blot
Q42985987An autoantibody cross-reactive to hepatitis C virus core and a host nuclear antigen
Q77873002An immunodominant epitope on DNA topoisomerase I is conformational in nature: heterogeneity in its recognition by systemic sclerosis sera
Q67490204Analysis of an immunodominant epitope of topoisomerase I in patients with systemic sclerosis
Q48295923Analysis of genomic clones of the murine U1RNA-associated 70-kDa protein reveals a high evolutionary conservation of the protein between human and mouse
Q74133507And the beat goes on: discovery of "new" autoantigens
Q55241731Antibodies to Retroviral Proteins and Reverse Transcriptase Activity in Patients With Essential Cryoglobulinemia
Q45788411Antibodies to human immunodeficiency virus (HIV-1) in autoimmune diseases: primary Sjögren's syndrome, systemic lupus erythematosus, rheumatoid arthritis and autoimmune thyroid diseases
Q67704954Antigenic domains on the U1 small nuclear ribonucleoprotein-associated 70K polypeptide: A comparison of regions selectively recognized by human and mouse autoantibodies and by monoclonal antibodies
Q37950626Antinuclear antibody determination methods
Q44640805Are retroviruses involved in the pathogenesis of SLE? Evidence demonstrated by molecular analysis of nucleic acids from SLE patients' plasma
Q67599007Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme disease
Q42616223Autoantibodies from patients with systemic lupus erythematosus bind a shared sequence of SmD and Epstein-Barr virus-encoded nuclear antigen EBNA I.
Q73251249Autoantibodies recognizing proteins copurified with PCNA in patients with connective tissue diseases
Q69353745Autoantibodies to DNA topoisomerase II in cryptogenic fibrosing alveolitis and connective tissue disease
Q36436250Autoantibodies to intracellular autoantigens and their B-cell epitopes: molecular probes to study the autoimmune response.
Q28207765Autoimmunity, polyclonal B-cell activation and infection
Q40968705Autoreactive human T cell lines recognizing ribosomal protein L7.
Q45786978B cell epitope on the U1 snRNP‐C autoantigen contains a sequence similar to that of the herpes simplex virus protein
Q37851311Cell biology of the snRNP particles
Q60449621Chapter 6 The Use of Autoantibodies in the Study of Nuclear and Chromosomal Organization
Q41482629Characterization of an HLA-DR4-restricted T cell clone recognizing a protein moiety of small nuclear ribonucleoproteins (UsnRNP).
Q24305104Cloning and domain structure of the mammalian splicing factor U2AF
Q37365085Comparative analysis of antibody and cell-mediated autoimmunity to transaldolase and myelin basic protein in patients with multiple sclerosis
Q24316396Construction of a transcription map around the gene for ataxia telangiectasia: identification of at least four novel genes
Q37879615Correlation between chlamydial infection and autoimmune response: molecular mimicry between RNA polymerase major sigma subunit from Chlamydia trachomatis and human L7.
Q38660157Current concepts of neuropsychiatric systemic lupus erythematosus (NP-SLE)
Q34755046Defects in virion production caused by mutations affecting the C-terminal portion of the Moloney murine leukemia virus capsid protein
Q35602755Definition of a discontinuous immunodominant epitope at the NH2 terminus of the La/SS-B ribonucleoprotein autoantigen
Q42980909Detection of Hepatitis C Virus Antibody in the Absence of Viral RNA in Patients with Autoimmune Hepatitis
Q43729486Detection of antibodies to HIV-1 gp41- and HLA class II antigen-derived peptides in SLE patients
Q34910262Detection of autoantibodies to ribosomal P protein using recombinant autoantigen in a quantitative immunoassay.
Q34317089Determination of an epitope of the diffuse systemic sclerosis marker antigen DNA topoisomerase I: sequence similarity with retroviral p30gag protein suggests a possible cause for autoimmunity in systemic sclerosis
Q41318437Distribution of human endogenous retrovirus HERV-K genomes in humans and different primates
Q37791690Do infections facilitate the emergence of systemic sclerosis?
Q24642604Early targets of nuclear RNP humoral autoimmunity in human systemic lupus erythematosus
Q69773227Elevation of the levels of SmB, B' and D proteins but not that of the La (SS-B) antigen during HSV infections
Q37649659Endogenous retroviral pathogenesis in lupus
Q41137058Epitope patterns of Anti-RNP antibodies in rheumatic diseases evidence for an antigen-driven autoimmune response
Q35832053Epitopes of human immunodeficiency virus regulatory proteins tat, nef, and rev are expressed in normal human tissue
Q41128916Evolution and biological significance of human retroelements
Q41438943Features of autoantigens.
Q24621357Fine epitope mapping of the human SS-B/La protein. Identification of a distinct autoepitope homologous to a viral gag polyprotein
Q33534690Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins
Q40431527Follicular Dendritic Cells and Infection by Human Immunodeficiency Virus Type 1—A Crucial Target Cell and Virus Reservoir
Q53359978Frequency and significance of antibodies to P450IID6 protein in Japanese patients with chronic hepatitis C.
Q67987624HLA class II restriction of autoantibody production in patients with systemic lupus erythematosus
Q39317795HTLV-I associated myelopathy: a case of viral-induced auto-immunity
Q36686295Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs
Q41751993Heterogeneity of RNP and Sm autoantigens in relation to the cell sources and the activated state of the cells
Q36497719Human RNA "rumor" viruses: the search for novel human retroviruses in chronic disease
Q34248273Human Ro ribonucleoprotein particles: characterization of native structure and stable association with the La polypeptide
Q33536189Human T cell leukemia virus type-I and rheumatoid arthritis
Q36870307Human T-cell lymphotropic virus (HTLV)-related endogenous sequence, HRES-1, encodes a 28-kDa protein: a possible autoantigen for HTLV-I gag-reactive autoantibodies
Q41664725Human anti-Ro autoantibodies bind peptides accessible to the surface of the native Ro autoantigen
Q36350643Human anti-p68 autoantibodies recognize a common epitope of U1 RNA containing small nuclear ribonucleoprotein and influenza B virus
Q24677052Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas
Q36109600Human endogenous retroviruses and their possible impact on dermatology.
Q35369410Human endogenous retroviruses: nature, occurrence, and clinical implications in human disease
Q47702950Humoral aspects of polymyositis/dermatomyositis
Q38146984Humoral autoimmunity in systemic rheumatic disease. A review.
Q36494607IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice
Q28208168Identification of an immunodominant epitope on RNA polymerase III recognized by systemic sclerosis sera: application to enzyme-linked immunosorbent assay
Q24633425Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors
Q40820568Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.
Q93511968Immunity to viruses
Q44862389Immunochemical analysis of an arginine-rich systemic lupus erythematosus autoepitope
Q41220119Immunopathogenesis of systemic sclerosis
Q40656756Immunopathogenesis of systemic sclerosis: possible role of retroviruses
Q71752162Immunopathology of primary biliary cirrhosis
Q41417294Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane
Q37625577Infection--genetics relationship in systemic lupus erythematosus.
Q33844647Influenza viruses induce autoantibodies to a brain-specific 37-kDa protein in rabbit
Q34576096Interactions between autoimmunity and molecular and cell biology. Bridges between clinical and basic sciences
Q24338971Isolation of complementary DNA for bullous pemphigoid antigen by use of patients' autoantibodies
Q36746396Key residues revealed in a major conformational epitope of the U1-70K protein
Q34299845Key sequences involved in the spreading of the systemic autoimmune response to spliceosomal proteins
Q45785432Lack of relationship between human immunodeficiency virus infection and systemic lupus erythematosus
Q40863475Localization of autoepitopes on the PCM-1 autoantigen using scleroderma sera with autoantibodies against the centrosome
Q45178223Major Autoantigenic Sites of the (U1) Small Nuclear Ribonucleoprotein-Specific 68-kDa Protein
Q45188961Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B'' and their cognate RNAs
Q36751110Mapping epitopes of U1-70K autoantibodies at single-amino acid resolution
Q35333170Mapping of epitopes recognized by anti-(U1)RNP autoantibodies
Q40928703Mechanisms of the pathogenic autoimmune response in lupus: prospects for specific immunotherapy
Q33695798Mechanisms of viral pathogenesis in rheumatic disease
Q35630484Membrane expression of nuclear antigens: a model for autoimmunity in Sjogren's syndrome?
Q28236216Mixed connective tissue disease
Q35847783Mixed connective tissue disease with interstitial pneumonia in HTLV-1 carrier: case report and review of the literature
Q24297302Molecular analysis of the 60-kDa human Ro ribonucleoprotein
Q40486179Molecular biology of autoantigens and new insights into autoimmunity
Q41201783Molecular biology of autoantigens in rheumatic diseases
Q24609151Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles
Q35333128Molecular mimicry and autoantigens in connective tissue diseases
Q37146122Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE.
Q34684816Molecular mimicry of human endothelial cell antigen by autoantibodies to nonstructural protein 1 of dengue virus
Q37552271Multiple overlapping homologies between two rheumatoid antigens and immunosuppressive viruses
Q36467450No significant correlation between specific antibodies to mouse mammary tumour virus and human cancer
Q36677450Nuclear RNA-binding Proteins
Q41500830Nucleosome-driven autoimmune response in lupus. Pathogenic T helper cell epitopes and costimulatory signals
Q36363997Oligodendrocyte-specific expression and autoantigenicity of transaldolase in multiple sclerosis
Q36840285Pathogenesis of SLE: immunopathology in man.
Q41852549Plasmacytoid dendritic cells in the duodenum of individuals diagnosed with myalgic encephalomyelitis are uniquely immunoreactive to antibodies to human endogenous retroviral proteins.
Q41140044Predicting Antigenic Determinants of Autoantigens
Q36351149Preferential nuclear compartmentalization of endogenous mink cell focus-forming-related retroviral transcripts
Q41438933RNA recognition by autoantigens and autoantibodies
Q41112963RNA surfaces as functional mimetics of proteins
Q69425749Rapid clearance of the lupus antigen Sm is delayed by autoantibody: a possible mechanism of autoimmunity perpetuation
Q35610673Reaction of anti-OJ autoantibodies with components of the multi-enzyme complex of aminoacyl-tRNA synthetases in addition to isoleucyl-tRNA synthetase
Q67666300Recombinant 70-kD protein used for determination of autoantigenic epitopes recognized by anti-RNP sera
Q38301671Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.
Q43722270Repetitive p68-autoantigen specific epitopes recognized by human anti-(U1) small nuclear ribonucleoprotein autoantibodies
Q37204656Retrovirus in salivary glands from patients with Sjögren's syndrome
Q40631119Retroviruses and autoimmune rheumatic diseases
Q41225515Retroviruses and systemic lupus erythematosus
Q40468530Retroviruses and the pathogenesis of systemic sclerosis.
Q36218578Ribonucleoprotein particles in cellular processes
Q33848284Role of antigen selectivity in autoimmune responses to the Ku (p70/p80) antigen
Q35084896Role of endogenous retroviruses in autoimmune diseases
Q36738984Role of intermolecular/intrastructural B- and T-cell determinants in the diversification of autoantibodies to ribonucleoprotein particles
Q42674837Sequential autoantigenic determinants of the small nuclear ribonucleoprotein Sm D shared by human lupus autoantibodies and MRL lpr/lpr antibodies
Q46106079Serodiagnosis of Wegener's granulomatosis: pathobiologic and clinical implications
Q41096261Structure and expression of a Xenopus gene encoding an snRNP protein (U1 70K).
Q48061610Structure and expression of a plant U1 snRNP 70K gene: alternative splicing of U1 snRNP 70K pre-mRNAs produces two different transcripts
Q33255074Structure and expression of the Drosophila melanogaster gene for the U1 small nuclear ribonucleoprotein particle 70K protein
Q41972255Structure of the small nuclear RNP particle U1: identification of the two structural protuberances with RNP-antigens A and 70K
Q40530121Structure-probing of U1 snRNPs gradually depleted of the U1-specific proteins A, C and 70k. Evidence that A interacts differentially with developmentally regulated mouse U1 snRNA variants
Q38175446Systemic lupus erythematosus and human endogenous retroviruses
Q36707517Systemic lupus erythematosus: RNA-protein autoantigens, models of disease heterogeneity, and theories of etiology
Q41301655T cell lines recognizing the 70-kD protein of U1 small nuclear ribonucleoprotein (U1snRNP)
Q34779998The U1-snRNP complex: structural properties relating to autoimmune pathogenesis in rheumatic diseases
Q38289890The amino-terminal domain of yeast U1-70K is necessary and sufficient for function
Q24294606The complete primary structure of the human snRNP E protein
Q35192913The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection
Q40482959The occurrence of systemic lupus erythematosus in an asymptomatic carrier of human T-cell lymphotropic virus type I.
Q48018433The plant U1 small nuclear ribonucleoprotein particle 70K protein interacts with two novel serine/arginine-rich proteins
Q41225538The potential roles of endogenous retroviruses in autoimmunity
Q43794940The presence of antibodies to purified p24gag protein of HTLV-I in sera of patients with systemic lupus erythematosus (SLE)
Q33927166The role of an autoantigen, histidyl-tRNA synthetase, in the induction and maintenance of autoimmunity
Q27932931The yeast homolog of the U1 snRNP protein 70K is encoded by the SNP1 gene
Q37783216Theoretical and experimental approaches to generalized autoimmunity
Q34731092Therapy of systemic lupus erythematosus: a look into the future
Q38707294Type W Human Endogenous Retrovirus (HERV-W) Integrations and Their Mobilization by L1 Machinery: Contribution to the Human Transcriptome and Impact on the Host Physiopathology.

Search more.