The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development.

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The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2012-07-441311
P932PMC publication ID3507145
P698PubMed publication ID23033267
P5875ResearchGate publication ID231864148

P50authorStephanie S. WatowichQ39631534
P2093author name stringYong-Jun Liu
Huiyuan Zhang
Ananda W Goldrath
Haiyan S Li
Kalyan C Nallaparaju
Cliff Y Yang
P2860cites workId2 expression delineates differential checkpoints in the genetic program of CD8α+ and CD103+ dendritic cell lineagesQ24617939
Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell developmentQ24645273
ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cellsQ24672345
Regulation of Id2 expression by CCAAT/enhancer binding protein betaQ24791043
Effects of administration of progenipoietin 1, Flt-3 ligand, granulocyte colony-stimulating factor, and pegylated granulocyte-macrophage colony-stimulating factor on dendritic cell subsets in miceQ28204960
Differential Interactions of Id Proteins with Basic-Helix-Loop-Helix Transcription FactorsQ28245175
STAT3 regulates cytokine-mediated generation of inflammatory helper T cellsQ28286840
Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-BQ28293931
IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursorsQ29618425
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factorQ29619247
Charting histone modifications and the functional organization of mammalian genomesQ29620707
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency.Q30368393
Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cellsQ30873503
Id2 is a primary partner for the E2-2 basic helix-loop-helix transcription factor in the human placentaQ33204651
The origin and development of nonlymphoid tissue CD103+ DCs.Q33590397
Transcriptional profiling identifies Id2 function in dendritic cell developmentQ34179059
STAT3 controls myeloid progenitor growth during emergency granulopoiesisQ34193520
Transcriptional programming of the dendritic cell networkQ34249412
Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiationQ34914457
Dendritic cell (DC)-specific targeting reveals Stat3 as a negative regulator of DC functionQ34997011
Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response.Q35346365
Nonredundant roles for Stat5a/b in directly regulating Foxp3Q35828667
Effect of transcription-factor concentrations on leukemic stem cells.Q35848111
STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophilsQ35848810
Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell developmentQ36227877
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivoQ36371293
The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3Q36371303
GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cellsQ36398839
Id2 and Id3 inhibit development of CD34(+) stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. Evidence for a lymphoid origin of pre-DC2.Q36404588
Naturally occurring dominant negative variants of Stat5.Q36563461
Dendritic cell homeostasisQ37157975
Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determinationQ37259798
E and ID proteins branch out.Q37400603
The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsetsQ37412212
The CD8+ dendritic cell subsetQ37700814
Origin and development of dendritic cellsQ37700819
Development and functional specialization of CD103+ dendritic cells.Q37700854
STAT5 in B cell development and leukemiaQ37708692
Mechanisms regulating dendritic cell specification and developmentQ37802420
STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbetaQ39714689
The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8Q40352693
Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cellsQ41477085
Natural interferon alpha/beta-producing cells link innate and adaptive immunityQ41748252
Transcriptional regulator Id2 mediates CD8+ T cell immunity.Q46760945
The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasisQ47734606
Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivoQ50885261
Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrowQ51975671
C/EBPbeta is required for 'emergency' granulopoiesisQ53619729
The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent MannerQ61783457
Granulocyte macrophage colony stimulating factor induced changes in cellular adhesion molecule expression and adhesion to endothelium: in-vitro and in-vivo studies in manQ69492157
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)4363-4373
P577publication date2012-10-01
P1433published inBloodQ885070
P1476titleThe signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development
P478volume120

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cites work (P2860)
Q364277323,3'-Diindolylmethane Inhibits Flt3L/GM-CSF-induced-bone Marrow-derived CD103(+) Dendritic Cell Differentiation Regulating Phosphorylation of STAT3 and STAT5.
Q37322150A type I IFN-Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors.
Q58096557AAV-Vectored Fms-Related Tyrosine Kinase 3 Ligand Inhibits CD34 Progenitor Cell Engraftment in Humanized Mice
Q35866588Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Q48645834Blocking the bFGF/STAT3 interaction through specific signaling pathways induces apoptosis in glioblastoma cells
Q37334492Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the antitumor efficacy of dendritic cells
Q41352500Dendritic Cell Subsets in Asthma: Impaired Tolerance or Exaggerated Inflammation?
Q27022894Diversification of dendritic cell subsets: Emerging roles for STAT proteins
Q42002425E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation
Q35742668Efficient Generation of Plasmacytoid Dendritic Cell from Common Lymphoid Progenitors by Flt3 Ligand
Q38934112Epigenetic program and transcription factor circuitry of dendritic cell development
Q40239444Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs
Q61118475FGL2 promotes tumor progression in the CNS by suppressing CD103 dendritic cell differentiation
Q41255523GM-CSF in murine psoriasiform dermatitis: Redundant and pathogenic roles uncovered by antibody-induced neutralization and genetic deficiency.
Q89698021Human Plasmacytoid Dendritic Cells and Cutaneous Melanoma
Q35205506Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation
Q34055968Innate immune regulation by STAT-mediated transcriptional mechanisms.
Q44823677Interleukin-2-mediated inhibition of dendritic cell development correlates with decreased CD135 expression and increased monocyte/macrophage precursors
Q38221347Intestinal dendritic cells in the regulation of mucosal immunity
Q40417690JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa.
Q90314834Leukemia Inhibitory Factor Inhibits Plasmacytoid Dendritic Cell Function and Development
Q90661514MicroRNA-148a facilitates inflammatory dendritic cell differentiation and autoimmunity by targeting MAFB
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Q26752279Origin, Localization, and Immunoregulatory Properties of Pulmonary Phagocytes in Allergic Asthma
Q38239650Plasmacytoid dendritic cells: development, functions, and role in atherosclerotic inflammation
Q37208020Regulation of Dendritic Cell Differentiation in Bone Marrow during Emergency Myelopoiesis
Q89550727Regulation of Transcription Factor E2-2 in Human Plasmacytoid Dendritic Cells by Monocyte-Derived TNFα
Q91910342STAT Family Protein Expression and Phosphorylation State during moDC Development Is Altered by Platinum-Based Chemotherapeutics
Q92704401STAT3 Inhibits CD103+ cDC1 Vaccine Efficacy in Murine Breast Cancer
Q89157989STAT3 in Tumor-Associated Myeloid Cells: Multitasking to Disrupt Immunity
Q38835846STAT3 signaling in immunity
Q48150411Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.
Q90540850Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution
Q37495470The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids
Q36731249The multifaceted biology of plasmacytoid dendritic cells
Q38193807The role of dendritic cells in graft-versus-tumor effect
Q36949912The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2
Q26779410Transcriptional Regulation of Mononuclear Phagocyte Development
Q38182644Transcriptional control of early T and B cell developmental choices
Q34517731miR-22 controls Irf8 mRNA abundance and murine dendritic cell development

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