The overactive bladder: review of current pharmacotherapy in adults. Part 1: pathophysiology and anticholinergic therapy

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The overactive bladder: review of current pharmacotherapy in adults. Part 1: pathophysiology and anticholinergic therapy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1517/14656566.7.5.509
P698PubMed publication ID16553567

P2093author name stringRajinder Singh
Jason John
Manit Arya
Hitendra R H Patel
Arun Sahai
Mohammed Shamim Khan
P2860cites workHow widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence studyQ28202479
Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivoQ28379545
Function, signal transduction mechanisms and plasticity of presynaptic muscarinic receptors in the urinary bladderQ33539501
The activation of bladder wall afferent nervesQ33542438
Solifenacin appears effective and well tolerated in patients with symptomatic idiopathic detrusor overactivity in a placebo- and tolterodine-controlled phase 2 dose-finding study.Q34543969
EnterocystoplastyQ34559851
Effectiveness of anticholinergic drugs compared with placebo in the treatment of overactive bladder: systematic reviewQ34950386
Pharmacologic perspective on the physiology of the lower urinary tractQ35031200
Urinary incontinence: newer pharmacotherapeutic trendsQ35539138
Management of overactive bladderQ35671074
The autonomous bladder: a view of the origin of bladder overactivity and sensory urgeQ35685704
Pharmacologic therapy of lower urinary tract dysfunction.Q35692493
Darifenacin, an M3 selective receptor antagonist, is an effective and well-tolerated once-daily treatment for overactive bladderQ35710439
Cost-effectiveness analysis of extended-release formulations of oxybutynin and tolterodine for the management of urge incontinenceQ35938505
The effects of antimuscarinic treatments in overactive bladder: a systematic review and meta-analysisQ36122988
Tolterodine--a new bladder selective muscarinic receptor antagonist: preclinical pharmacological and clinical dataQ36856528
Pharmacokinetics, efficacy, and safety of intravesical formulation of oxybutynin in patients with detrusor overactivityQ39407286
A neurologic basis for the overactive bladderQ41679682
A myogenic basis for the overactive bladderQ41679687
Efficacy of bladder training in older women with urinary incontinenceQ41824956
Distribution of afferent axons in the bladder of ratsQ42482443
Does concomitant stress incontinence alter the efficacy of tolterodine in patients with overactive bladder?Q42631219
Long-term open-label solifenacin treatment associated with persistence with therapy in patients with overactive bladder syndromeQ42648179
Comparison of symptom severity and treatment response in patients with incontinent and continent overactive bladderQ42660202
Overactive bladder: a clinical entity or a marketing hype?Q42699336
Trospium chloride improves overactive bladder symptoms: a multicenter phase III trialQ43310817
Tolterodine once-daily: superior efficacy and tolerability in the treatment of the overactive bladder.Q43542367
A quantitative analysis of purinoceptor expression in human fetal and adult bladdersQ43601082
Tolterodine: a safe and effective treatment for older patients with overactive bladderQ43674684
Tolterodine reduces the number of urge incontinence episodes in patients with an overactive bladderQ43715524
Long-term safety of extended-release oxybutynin chloride in a community-dwelling population of participants with overactive bladder: a one-year studyQ43981420
Efficacy, safety, and tolerability of extended-release once-daily tolterodine treatment for overactive bladder in older versus younger patientsQ44004623
Activation and sensitisation of low and high threshold afferent fibres mediated by P2X receptors in the mouse urinary bladderQ44013297
Long-term safety, tolerability and efficacy of extended-release tolterodine in the treatment of overactive bladderQ44035116
The minor population of M3-receptors mediate contraction of human detrusor muscle in vitroQ44068017
Mechanisms underlying the recovery of urinary bladder function following spinal cord injuryQ44159727
Autonomous activity in the isolated guinea pig bladderQ44276818
Oxybutynin in bladder spasm, neurogenic bladder, and enuresisQ44315476
Comparative efficacy and safety of transdermal oxybutynin and oral tolterodine versus placebo in previously treated patients with urge and mixed urinary incontinenceQ44534042
Prospective, randomized, double-blind study of the efficacy and tolerability of the extended-release formulations of oxybutynin and tolterodine for overactive bladder: results of the OPERA trialQ44559884
Pharmacokinetics, metabolism, and saliva output during transdermal and extended-release oral oxybutynin administration in healthy subjectsQ44559886
Clinical efficacy and tolerability of extended‐release tolterodine and immediate‐release oxybutynin in Japanese and Korean patients with an overactive bladder: a randomized, placebo‐controlled trialQ44655032
Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cellsQ44683028
Efficacy of antimuscarinic therapy for overactive bladder with varying degrees of incontinence severityQ44721051
Randomized, double-blind placebo- and tolterodine-controlled trial of the once-daily antimuscarinic agent solifenacin in patients with symptomatic overactive bladderQ44756641
Signal transduction underlying carbachol-induced contraction of human urinary bladderQ44760506
In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats.Q44922103
Urodynamic effects and safety of modified intravesical oxybutynin chloride in patients with neurogenic detrusor overactivity: 3 years experienceQ45001317
Treatment of urge-predominant mixed urinary incontinence with tolterodine extended release: a randomized, placebo-controlled trialQ45012360
Health-related quality of life of Japanese patients with overactive bladder treated with extended-release tolterodine or immediate-release oxybutynin: a randomized, placebo-controlled trialQ45083861
Randomized, double-blind placebo controlled trial of the once daily antimuscarinic agent solifenacin succinate in patients with overactive bladderQ45148608
Improved quality of life in patients with overactive bladder symptoms treated with solifenacinQ45215936
Intravesical oxybutynin chloride: experience with 42 patientsQ46111859
A pooled analysis of three phase III studies to investigate the efficacy, tolerability and safety of darifenacin, a muscarinic M3 selective receptor antagonist, in the treatment of overactive bladderQ46445206
Comparison of darifenacin and oxybutynin in patients with overactive bladder: assessment of ambulatory urodynamics and impact on salivary flowQ46528879
Efficacy and tolerability of darifenacin, a muscarinic M3 selective receptor antagonist (M3 SRA), compared with oxybutynin in the treatment of patients with overactive bladderQ46535726
Long-term safety, tolerability and efficacy of extended-release tolterodine in the treatment of overactive bladder in Japanese patientsQ46538992
Propiverine versus tolterodine: efficacy and tolerability in patients with overactive bladder.Q46557454
Treatment of overactive bladder in the older patient: pooled analysis of three phase III studies of darifenacin, an M3 selective receptor antagonistQ46577108
Solifenacin is effective for the treatment of OAB dry patients: a pooled analysisQ46591360
Estimated economic costs of overactive bladder in the United StatesQ46914426
A comparison of spontaneous and nerve-mediated activity in bladder muscle from man, pig and rabbit.Q51839265
The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society.Q53317478
A placebo-controlled, multicentre study comparing the tolerability and efficacy of propiverine and oxybutynin in patients with urgency and urge incontinence.Q53342637
Pharmacokinetics and metabolism of darifenacin in the mouse, rat, dog and man.Q53958530
Behavioral vs Drug Treatment for Urge Urinary Incontinence in Older WomenQ56639150
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpharmacotherapyQ701216
P304page(s)509-527
P577publication date2006-04-01
P1433published inExpert Opinion on PharmacotherapyQ5421212
P1476titleThe overactive bladder: review of current pharmacotherapy in adults. Part 1: pathophysiology and anticholinergic therapy
P478volume7

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cites work (P2860)
Q63431938Minimally Invasive and Regenerative Therapeutics
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