Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation

scientific article

Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1029979011
P356DOI10.1186/1479-5876-10-217
P932PMC publication ID3508881
P698PubMed publication ID23113945
P5875ResearchGate publication ID232744072

P50authorSimon LovestoneQ30582986
Iwona KłoszewskaQ38633661
Hilkka SoininenQ38636823
Lars-Olof WahlundQ38637441
Patrizia MecocciQ46713839
Jane Z. ReedQ50731852
Magda N. TsolakiQ57073392
Ines GrecoQ58826728
Bruno VellasQ66877204
Christian SpengerQ114432264
Joanna Riddoch-ContrerasQ114432268
P2093author name stringAndrew Simmons
Julie Barnes
Nicola Day
P2860cites workThe KUPKB: a novel Web application to access multiomics data on kidney diseaseQ28260266
Reorganizing the protein space at the Universal Protein Resource (UniProt)Q29547338
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's diseaseQ29614881
Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controlsQ33676329
Blood-based biomarkers of Alzheimer's disease: challenging but feasibleQ33824444
Cerebrospinal fluid and plasma biomarkers in Alzheimer diseaseQ34098866
uPAR: a versatile signalling orchestratorQ34162183
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer diseaseQ35034130
Proteome-based plasma markers of brain amyloid-β deposition in non-demented older individualsQ35076119
Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkersQ36787240
Elevated C-reactive protein levels are associated with prevalent dementia in the oldest-oldQ37339094
Regulation of cell signalling by uPAR.Q37660895
The urokinase receptor: focused cell surface proteolysis, cell adhesion and signalingQ37663098
Biomarkers for Alzheimer's disease therapeutic trialsQ37815749
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different speciesQ38508018
Sialic acid, homocysteine and CRP: potential markers for dementiaQ43274128
MRI measures of Alzheimer's disease and the AddNeuroMed studyQ43497894
Increased expression of the urokinase plasminogen-activator receptor in amyloid beta peptide-treated human brain microglia and in AD brainsQ43868531
Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors.Q44291669
Plasma transthyretin as a candidate marker for Alzheimer's diseaseQ44768899
A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's diseaseQ46063519
Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's diseaseQ46707483
Amyloid β-Protein Stimulates the Expression of Urokinase-type Plasminogen Activator (uPA) and Its Receptor (uPAR) in Human Cerebrovascular Smooth Muscle CellsQ48306498
Expression of matrix metalloproteinase-9 and urinary-type plasminogen activator in Alzheimer's disease brainQ48896798
AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North AmericaQ49041459
The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels.Q51605501
The AddNeuroMed framework for multi-centre MRI assessment of Alzheimer's disease: experience from the first 24 months.Q51824464
Novel systemic markers for patients with Alzheimer disease? - a pilot study.Q53296345
Is there a relationship between high C-reactive protein (CRP) levels and dementia?Q53305180
AddNeuroMed--the European collaboration for the discovery of novel biomarkers for Alzheimer's diseaseQ95800564
P921main subjectAlzheimer's diseaseQ11081
in silicoQ192572
biomarkerQ864574
P304page(s)217
P577publication date2012-10-31
P1433published inJournal of Translational MedicineQ15716664
P1476titleAlzheimer's disease biomarker discovery using in silico literature mining and clinical validation
P478volume10

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cites work (P2860)
Q51760901A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication.
Q91919314A Preliminary Cohort Study Assessing Routine Blood Analyte Levels and Neurological Outcome after Spinal Cord Injury
Q48036293Advancing Alzheimer's research: A review of big data promises
Q33752058Circulating biomarkers that predict incident dementia
Q47626694Current practices and future outlook on the integration of biomarkers in the drug development process
Q45934744Editorial: Painting by numbers: using modern approaches to analyse and visualise clinical and research data.
Q38419506Linking hypothetical knowledge patterns to disease molecular signatures for biomarker discovery in Alzheimer's disease
Q35811161NeuroTransDB: highly curated and structured transcriptomic metadata for neurodegenerative diseases
Q39044367The developing landscape of diagnostic and prognostic biomarkers for spinal cord injury in cerebrospinal fluid and blood
Q38592069Translation of Pre-Clinical Studies into Successful Clinical Trials for Alzheimer's Disease: What are the Roadblocks and How Can They Be Overcome?

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