scholarly article | Q13442814 |
P356 | DOI | 10.1007/BF00273412 |
P698 | PubMed publication ID | 3165725 |
P2093 | author name string | W Plunkett | |
V Heinemann | |||
D Murray | |||
R E Meyn | |||
R Walters | |||
P2860 | cites work | High-dose cytosine arabinoside: treatment and cellular pharmacology of chronic myelogenous leukemia blast crisis | Q33452103 |
A pilot study of high-dose 1-beta-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: clinical response and pharmacology. | Q33483006 | ||
Application of arabinofuranosyl cytosine in the kinetic analysis and quantitation of DNA repair in human cells after ultraviolet irradiation | Q34252372 | ||
Applicability of the alkaline elution procedure as modified for the measurement of DNA damage and its repair in nonradioactively labeled cells | Q35074646 | ||
Improved microfluorometric DNA determination in biological material using 33258 Hoechst | Q36895188 | ||
NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals | Q37316864 | ||
Kinetics of Inhibition of Deoxynucleotide-Polymerizing Enzyme Activities from Normal and Leukemic Human Cells by 9-beta-D-Arabinofuranosyladenine 5'-Triphosphate and 1-beta-D-Arabinofuranosylcytosine 5'-Triphosphate | Q40661875 | ||
Phase I-II clinical and pharmacologic studies of high-dose cytosine arabinoside in refractory leukemia | Q40805621 | ||
The effect of cytosine arabinoside on the frequency of single-strand breaks in DNA of mammalian cells following irradiation or chemical treatment | Q41290809 | ||
Saturation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate accumulation in leukemia cells during high-dose 1-beta-D-arabinofuranosylcytosine therapy | Q41324222 | ||
Experimental antitumor activity of aminoanthraquinones | Q41487334 | ||
High-dose cytosine arabinoside and mitoxantrone: a highly effective regimen in refractory acute myeloid leukemia | Q42216165 | ||
High-dose cytosine arabinoside therapy for refractory leukemia | Q42244165 | ||
DNA-binding specificity and RNA polymerase inhibitory activity of bis(aminoalkyl)anthraquinones and bis(methylthio)vinylquinolinium iodides | Q42262844 | ||
Relationship between cytotoxicity and DNA damage in mammalian cells treated with anthracenedione derivatives | Q45283553 | ||
Treatment of poor risk acute leukemia with sequential high-dose ARA-C and asparaginase. | Q53553679 | ||
Mitozantrone-induced toxicity and DNA strand breaks in leukaemic cells. | Q54415532 | ||
Interactions of a new antitumor agent, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-9,10-anthracenedione, with nucleic acids | Q62590663 | ||
Schedule-dependent synergism for the combination of 1-beta-D-arabinofuranosylcytosine and daunorubicin | Q69733644 | ||
Phase I-II trial of mitoxantrone in acute leukemia | Q69832560 | ||
Mitozantrone and high-dose cytarabine in refractory adult acute myeloid leukaemia | Q69868917 | ||
The antitumor agent mitoxantrone binds cooperatively to DNA: evidence for heterogeneity in DNA conformation | Q69879901 | ||
Mitoxantrone affects topoisomerase activities in human breast cancer cells | Q70139548 | ||
Mitoxantrone as a single agent and in combination chemotherapy in patients with refractory acute leukemia | Q70385124 | ||
The efficiency of DNA strand-break repair in two fibrosarcoma tumors and in normal tissues of mice irradiated in vivo with X rays | Q70391667 | ||
Variation in normal and tumor tissue sensitivity of mice to ionizing radiation-induced DNA strand breaks in vivo | Q71096758 | ||
Lethal effects of 1-beta-D-arabinofuranosylcytosine incorporation into deoxyribonucleic acid during ultraviolet repair | Q71280277 | ||
Correlation of cytotoxicity with incorporation of ara-C into DNA | Q71302520 | ||
Interactions of the antitumor agents mitoxantrone and bisantrene with deoxyribonucleic acids studied by electron microscopy | Q71306385 | ||
DNA strand breaks caused by inhibitors of DNA synthesis: 1-beta-D-arabinofuranosylcytosine and aphidicolin | Q71614063 | ||
Studies in mouse L-cells on the incorporation of 1-beta-D-arabinofuranosylcytosine into DNA and on inhibition of DNA polymerase by 1-beta-D-arabinofuranosylcytosine 5'-triphosphate | Q71726732 | ||
Phase II trial of mitoxantrone in refractory acute leukemia | Q71733423 | ||
Accumulation of leukemic cell DNA strand breaks with adriamycin and cytosine arabinoside | Q71745518 | ||
Quantitation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in the leukemic cells from bone marrow and peripheral blood of patients receiving 1-beta-D-arabinofuranosylcytosine therapy | Q71998653 | ||
Inhibition of mammalian DNA polymerase by the 5'-triphosphate of 1-beta-d-arabinofuranosylcytosine and the 5'-triphosphate of 9-beta-d-arabinofuranoxyladenine | Q72310743 | ||
Fluorometric quantitation of single-stranded DNA: A method applicable to the technique of alkaline elution | Q72691303 | ||
Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells | Q72750026 | ||
P433 | issue | 3 | |
P921 | main subject | DNA damage | Q5205747 |
P304 | page(s) | 205-210 | |
P577 | publication date | 1988-01-01 | |
P1433 | published in | Cancer Chemotherapy and Pharmacology | Q326137 |
P1476 | title | Mitoxantrone-induced DNA damage in leukemia cells is enhanced by treatment with high-dose arabinosylcytosine | |
P478 | volume | 22 |
Q41843895 | Assessment of Drug Sensitivity in Hematopoietic Stem and Progenitor Cells from Acute Myelogenous Leukemia and Myelodysplastic Syndrome Ex Vivo |
Q73209536 | Dose-escalation study of single dose mitoxantrone in combination with timed sequential chemotherapy in patients with refractory or relapsing acute myelogenous leukemia |
Q73269119 | Early secondary acute myelogenous leukemia in breast cancer patients after treatment with mitoxantrone, cyclophosphamide, fluorouracil and radiation therapy |
Q62022698 | FLANG salvage chemotherapy is an effective regimen that offers a safe bridge to transplantation for patients with relapsed or refractory acute myeloid leukemia |
Q41132585 | Lack of involvement of reactive oxygen in the cytotoxicity of mitoxantrone, CI941 and ametantrone in MCF-7 cells: comparison with doxorubicin |
Q48724165 | Mitoxantrone-induced DNA strand breaks in cell-cultures of malignant human astrocytoma and glioblastoma tumors |
Q36657495 | Mitoxantrone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer |
Q41120664 | Mitoxantrone: a review of its pharmacological properties and use in acute nonlymphoblastic leukaemia |
Q34288371 | Nucleoside analogues: mechanisms of drug resistance and reversal strategies. |
Q54220320 | Quantification of topoisomerase-DNA complexes in leukemia cells from patients undergoing therapy with a topoisomerase-directed agent. |
Q36761725 | Timed-sequential chemotherapy as induction and/or consolidation regimen for younger adults with acute myelogenous leukemia |
Q41055118 | Treatment of childhood acute myeloid leukaemia |
Q33332473 | Treatment of patients with recurrent and primary refractory acute myelogenous leukemia using mitoxantrone and intermediate-dose cytarabine: a pharmacologically based regimen |
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