scholarly article | Q13442814 |
P2093 | author name string | Murali Prakriya | |
Richard S Lewis | |||
P2860 | cites work | TRP-PLIK, a bifunctional protein with kinase and ion channel activities | Q28143098 |
LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability | Q28198374 | ||
Potentiation and inhibition of Ca(2+) release-activated Ca(2+) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP(3) receptors | Q28360565 | ||
Calcium signaling mechanisms in T lymphocytes | Q32186061 | ||
Capacitative calcium entry channels | Q33539655 | ||
Store-operated calcium channels. | Q33602358 | ||
Regulation of cellular magnesium | Q33988740 | ||
Conductance and permeation of monovalent cations through depletion-activated Ca2+ channels (ICRAC) in Jurkat T cells | Q34040325 | ||
The TRP ion channel family. | Q34271602 | ||
Mechanisms of capacitative calcium entry | Q34330249 | ||
Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels. | Q36236139 | ||
Single channel properties and regulated expression of Ca(2+) release-activated Ca(2+) (CRAC) channels in human T cells | Q36293746 | ||
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores | Q36405355 | ||
Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes | Q36411768 | ||
Monovalent permeability, rectification, and ionic block of store-operated calcium channels in Jurkat T lymphocytes | Q36411979 | ||
Calcium channel selectivity for divalent and monovalent cations. Voltage and concentration dependence of single channel current in ventricular heart cells | Q36433886 | ||
Calcium channels: mechanisms of selectivity, permeation, and block | Q38175919 | ||
Gene regulation mediated by calcium signals in T lymphocytes | Q38302789 | ||
Monovalent cation permeability and Ca(2+) block of the store-operated Ca(2+) current I(CRAC )in rat basophilic leukemia cells | Q40745195 | ||
CaT1 and the calcium release-activated calcium channel manifest distinct pore properties. | Q40771397 | ||
Plasma membrane Ca2+ release-activated Ca2+ channels with a high selectivity for Ca2+ identified by patch-clamp recording in rat liver cells | Q40815484 | ||
Role of the phospholipase C-inositol 1,4,5-trisphosphate pathway in calcium release-activated calcium current and capacitative calcium entry | Q40816538 | ||
Stable activation of single Ca2+ release-activated Ca2+ channels in divalent cation-free solutions | Q40847413 | ||
Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels | Q40896605 | ||
Extracellular site for econazole-mediated block of Ca2+ release-activated Ca2+ current (Icrac) in T lymphocytes | Q41161693 | ||
Calcium-dependent enhancement of depletion-activated calcium current in Jurkat T lymphocytes | Q41222168 | ||
Mechanism of ion permeation through calcium channels | Q41560714 | ||
Store depletion and calcium influx | Q41630788 | ||
Single-channel properties of a volume-sensitive anion conductance. Current activation occurs by abrupt switching of closed channels to an open state | Q42976972 | ||
Dissociation of the store-operated calcium current I(CRAC) and the Mg-nucleotide-regulated metal ion current MagNuM. | Q43908345 | ||
Slow calcium-dependent inactivation of depletion-activated calcium current. Store-dependent and -independent mechanisms. | Q45970573 | ||
Single-channel recording of a store-operated Ca2+ channel in Jurkat T lymphocytes | Q46196366 | ||
Non-selective conductance in calcium channels of frog muscle: calcium selectivity in a single-file pore | Q48661114 | ||
The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency. | Q54019197 | ||
The variance of sodium current fluctuations at the node of Ranvier | Q54547719 | ||
CaT1 manifests the pore properties of the calcium-release-activated calcium channel | Q59064565 | ||
Calcium and barium permeation through calcium release-activated calcium (CRAC) channels | Q71567606 | ||
Non-specific effects of calcium entry antagonists in mast cells | Q72482001 | ||
Calcium release-activated calcium current in rat mast cells | Q72578616 | ||
P433 | issue | 5 | |
P304 | page(s) | 487-507 | |
P577 | publication date | 2002-05-01 | |
P1433 | published in | The Journal of General Physiology | Q1092259 |
P1476 | title | Separation and characterization of currents through store-operated CRAC channels and Mg2+-inhibited cation (MIC) channels | |
P478 | volume | 119 |
Q35690264 | 2-Aminoethoxydiphenyl borate as a common activator of TRPV1, TRPV2, and TRPV3 channels |
Q36430242 | 2-aminoethyl diphenyl borinate (2-APB) inhibits TRPM7 channels through an intracellular acidification mechanism |
Q41858588 | A mathematical model of T lymphocyte calcium dynamics derived from single transmembrane protein properties. |
Q28305026 | A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function |
Q36402834 | A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients |
Q24800118 | A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway |
Q35216959 | A stochastic view of lymphocyte motility and trafficking within the lymph node |
Q36412521 | A store-operated calcium channel in Drosophila S2 cells |
Q46630908 | A store-operated nonselective cation channel in human lymphocytes |
Q37343898 | ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry |
Q47296556 | Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N-terminus. |
Q48318699 | C-type natriuretic peptide activates a non-selective cation current in acutely isolated rat cardiac fibroblasts via natriuretic peptide C receptor-mediated signalling |
Q35135449 | CRAC channels: activation, permeation, and the search for a molecular identity |
Q59281178 | CRAC inhibitors: identification and potential |
Q38026795 | Ca(2+) release-activated Ca(2+) (CRAC) current, structure, and function. |
Q34184784 | Ca2+ modulation of Ca2+ release-activated Ca2+ channels is responsible for the inactivation of its monovalent cation current |
Q44274680 | Ca2+ selectivity and fatty acid specificity of the noncapacitative, arachidonate-regulated Ca2+ (ARC) channels |
Q35586564 | Ca2+/calcineurin signalling in cells of the immune system |
Q40578492 | CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells. |
Q43323174 | Calcium feedback mechanisms regulate oscillatory activity of a TRP-like Ca2+ conductance in C. elegans intestinal cells |
Q24338564 | Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability |
Q38967624 | Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation. |
Q33878792 | Calcium signaling in immune cells. |
Q47812856 | Cardiovascular and Hemostatic Disorders: SOCE and Ca2+ Handling in Platelet Dysfunction. |
Q35096887 | Cellular magnesium homeostasis |
Q40444267 | Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. |
Q36200598 | Characterization of Mg²⁺-regulated TRPM7-like current in human atrial myocytes |
Q28181413 | Characterization of the Protein Kinase Activity of TRPM7/ChaK1, a Protein Kinase Fused to the Transient Receptor Potential Ion Channel |
Q36493629 | Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels |
Q37601674 | Complex role of STIM1 in the activation of store-independent Orai1/3 channels. |
Q39434223 | Constitutive expression of a Mg2+-inhibited K+ current and a TRPM7-like current in human erythroleukemia cells |
Q92565999 | Critical parameters maintaining authentic CRAC channel hallmarks |
Q37019730 | Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis |
Q35693807 | Density of functional Ca2+ release-activated Ca2+ (CRAC) channels declines after T-cell activation |
Q37344099 | Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides |
Q57284399 | Depletion of plasma membrane-associated phosphoinositides mimics inhibition of TRPM7 channels by cytosolic Mg, spermine and pH |
Q35900737 | Detailed examination of Mg2+ and pH sensitivity of human TRPM7 channels |
Q40497039 | Distinct Ca(2+)-permeable cation currents are activated by internal Ca(2+)-store depletion in RBL-2H3 cells and human salivary gland cells, HSG and HSY. |
Q28755686 | Distinct properties of CRAC and MIC channels in RBL cells |
Q37601654 | Divergence of Ca(2+) selectivity and equilibrium Ca(2+) blockade in a Ca(2+) release-activated Ca(2+) channel |
Q35649670 | Dual-function ion channel/protein kinases: novel components of vertebrate magnesium regulatory mechanisms. |
Q40026601 | Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. |
Q38124446 | Emerging roles for native Orai Ca2+ channels in cardiovascular disease |
Q24656681 | Epithelial Ca2+ entry channels: transcellular Ca2+ transport and beyond |
Q39839646 | Evidence that TRPM7 is required for breast cancer cell proliferation. |
Q39683572 | Expression of Orai genes and I(CRAC) activation in the human retinal pigment epithelium |
Q45358086 | Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in human blood lymphocytes and Jurkat leukemia T cells |
Q40540310 | Fast Ca(2+)-dependent inactivation of the store-operated Ca2+ current (ISOC) in liver cells: a role for calmodulin. |
Q40452169 | Functional properties of endogenous receptor- and store-operated calcium influx channels in HEK293 cells. |
Q30483187 | Hair loss and defective T- and B-cell function in mice lacking ORAI1 |
Q33568917 | High glucose and diabetes enhanced store-operated Ca(2+) entry and increased expression of its signaling proteins in mesangial cells |
Q38830267 | Historical Overview of Store-Operated Ca(2+) Entry. |
Q36909704 | How many Orai's does it take to make a CRAC channel? |
Q37468456 | Identification of TRPM7 channels in human intestinal interstitial cells of Cajal |
Q36436527 | Identification of store-independent and store-operated Ca2+ conductances in Caenorhabditis elegans intestinal epithelial cells |
Q50233838 | Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry |
Q35691101 | Intermediate-conductance calcium-activated potassium channel KCa3.1 and chloride channel modulate chemokine ligand (CCL19/CCL21)-induced migration of dendritic cells |
Q37901394 | Ion channels as targets for cancer therapy |
Q35102159 | Ionic mechanisms and Ca2+ dynamics underlying the glucose response of pancreatic β cells: a simulation study |
Q34405737 | KCa3.1 and TRPM7 channels at the uropod regulate migration of activated human T cells |
Q40031559 | Local Ca2+ influx through Ca2+ release-activated Ca2+ (CRAC) channels stimulates production of an intracellular messenger and an intercellular pro-inflammatory signal. |
Q34180374 | MIC channels are inhibited by internal divalent cations but not ATP. |
Q30543682 | Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels |
Q37100002 | Methods for studying store-operated calcium entry |
Q28210275 | Mg2+ Homeostasis: The Mg2+nificent TRPM Chanzymes |
Q39815889 | Mg2+- and MgATP-inhibited and Ca2+/calmodulin-sensitive TRPM7-like current in hepatoma and hepatocytes |
Q36412396 | Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6. |
Q89127313 | Modulation of Mg2+ influx and cytoplasmic free Mg2+ concentration in rat ventricular myocytes |
Q44765821 | Modulation of plasma membrane calcium-ATPase activity by local calcium microdomains near CRAC channels in human T cells |
Q26793407 | Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai |
Q38716075 | Molecular mechanisms of STIM/Orai communication. |
Q35044896 | Monovalent cation (MC) current in cardiac and smooth muscle cells: regulation by intracellular Mg2+ and inhibition by polycations |
Q39737450 | Na(+)-independent Mg(2+) transport sensitive to 2-aminoethoxydiphenyl borate (2-APB) in vascular smooth muscle cells: involvement of TRPM-like channels |
Q38273256 | Natural and Synthetic Modulators of the TRPM7 Channel |
Q36159053 | Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7 |
Q57201013 | New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B |
Q46639569 | Non-quantal release of acetylcholine in guinea-pig airways: role of choline transporter |
Q58426379 | Oncogenic KRAS suppresses store-operated Ca 2+ entry and I CRAC through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines |
Q24293232 | Orai1 and STIM reconstitute store-operated calcium channel function |
Q24300383 | Orai1 is an essential pore subunit of the CRAC channel |
Q36296143 | Orai1 mutations alter ion permeation and Ca2+-dependent fast inactivation of CRAC channels: evidence for coupling of permeation and gating |
Q30560181 | Orai1-dependent calcium entry promotes skeletal muscle growth and limits fatigue |
Q36493612 | PIP2 activates TRPV5 and releases its inhibition by intracellular Mg2+. |
Q35051287 | Permeation through store-operated CRAC channels in divalent-free solution: potential problems and implications for putative CRAC channel genes |
Q26999694 | Permeation, regulation and control of expression of TRP channels by trace metal ions |
Q26864181 | Permeation, selectivity and gating in store-operated CRAC channels |
Q41943394 | Physiological pathway of magnesium influx in rat ventricular myocytes |
Q35111006 | Physiological role of Kv1.3 channel in T lymphocyte cell investigated quantitatively by kinetic modeling |
Q36766033 | Physiological roles of STIM1 and Orai1 homologs and CRAC channels in the genetic model organism Caenorhabditis elegans |
Q37429036 | Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel. |
Q34180818 | Polyvalent cations as permeant probes of MIC and TRPM7 pores |
Q44725330 | Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2. |
Q36493502 | Potentiation of TRPM7 inward currents by protons |
Q35540052 | Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism |
Q36295793 | Regulation of CRAC channel activity by recruitment of silent channels to a high open-probability gating mode |
Q44185277 | Regulation of Ca2+ release-activated Ca2+ channels by INAD and Ca2+ influx factor |
Q28573078 | Regulation of a TRPM7-like current in rat brain microglia |
Q42130263 | Role of InsP3 and ryanodine receptors in the activation of capacitative Ca2+ entry by store depletion or hypoxia in canine pulmonary arterial smooth muscle cells |
Q33851509 | Role of TRPM7 in Cancer: Potential as Molecular Biomarker and Therapeutic Target |
Q44593063 | Role of sarcoplasmic reticulum Ca2+ content in Ca2+ entry of bovine airway smooth muscle cells |
Q39980643 | Role of the alpha-kinase domain in transient receptor potential melastatin 6 channel and regulation by intracellular ATP. |
Q51024972 | Role of transient receptor potential melastatin type 7 channel in gastric cancer. |
Q40230127 | SLC41A2 encodes a plasma-membrane Mg2+ transporter |
Q35075129 | STIM and Orai: the long-awaited constituents of store-operated calcium entry |
Q39177870 | STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion |
Q24544990 | STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels |
Q79421872 | STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane |
Q39980884 | STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle |
Q34442494 | STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel |
Q39933072 | STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy |
Q36041652 | Sensitivity of TRPM7 channels to Mg2+ characterized in cell-free patches of Jurkat T lymphocytes |
Q34767859 | Sorting out MIC, TRP, and CRAC ion channels. |
Q36681735 | Sphingosine and FTY720 are potent inhibitors of the transient receptor potential melastatin 7 (TRPM7) channels. |
Q37192852 | Stim1 and Orai1 mediate CRAC currents and store-operated calcium entry important for endothelial cell proliferation |
Q54046109 | Store-Operated Calcium Channels. |
Q88210367 | Store-Operated Calcium Entry: An Historical Overview |
Q39142369 | Store-dependent and -independent modes regulating Ca2+ release-activated Ca2+ channel activity of human Orai1 and Orai3 |
Q40831873 | Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia |
Q26744698 | Store-operated Ca2+ channels in airway epithelial cell function and implications for asthma |
Q40645346 | Store-operated Ca2+ channels in prostate cancer epithelial cells: function, regulation, and role in carcinogenesis. |
Q40670996 | Store-operated Ca2+ current in prostate cancer epithelial cells. Role of endogenous Ca2+ transporter type 1. |
Q44308512 | Store-operated Ca2+ entry: dynamic interplay between endoplasmic reticulum, mitochondria and plasma membrane |
Q27014971 | Store-operated Orai channels: structure and function |
Q36185239 | TRPM2 and TRPM7: channel/enzyme fusions to generate novel intracellular sensors |
Q30361651 | TRPM7 |
Q36015320 | TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD? |
Q99610232 | TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity |
Q36295656 | TRPM7 channel is regulated by magnesium nucleotides via its kinase domain. |
Q40131433 | TRPM7 channel is sensitive to osmotic gradients in human kidney cells |
Q36092638 | TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations |
Q40237817 | TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells. |
Q24633941 | TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain |
Q37294005 | TRPM7-like channels are functionally expressed in oocytes and modulate post-fertilization embryo development in mouse |
Q98178396 | TRPM7/RPSA Complex Regulates Pancreatic Cancer Cell Migration |
Q44037373 | TRPV3 is a calcium-permeable temperature-sensitive cation channel. |
Q36105323 | Temperature and RyR1 regulate the activation rate of store-operated Ca²+ entry current in myotubes |
Q34600697 | The Mg2+ and Mg(2+)-nucleotide-regulated channel-kinase TRPM7. |
Q39905929 | The Orai1 severe combined immune deficiency mutation and calcium release-activated Ca2+ channel function in the heterozygous condition. |
Q37633873 | The Pathophysiologic Roles of TRPM7 Channel |
Q36042498 | The STIM1-ORAI1 microdomain |
Q34397161 | The TRP superfamily of cation channels |
Q34988284 | The cellular and molecular basis of store-operated calcium entry |
Q34572639 | The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k |
Q30480480 | The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions |
Q37597609 | The functional network of ion channels in T lymphocytes |
Q34498873 | The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations |
Q37597611 | The molecular physiology of CRAC channels |
Q38044616 | The role of Mg2+ in immune cells |
Q36447177 | The store-operated calcium entry pathways in human carcinoma A431 cells: functional properties and activation mechanisms |
Q35135517 | Transient receptor potential (TRP) channels as potential drug targets in respiratory disease |
Q36681384 | Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation |
Q35082756 | Transient receptor potential melastatin type 7 channel is critical for the survival of bone marrow derived mesenchymal stem cells |
Q47400897 | Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription. |
Q38631717 | Voltage gating at the selectivity filter of the Ca2+ release-activated Ca2+ channel induced by mutation of the Orai1 protein |
Q39757704 | Whole-cell recording of calcium release-activated calcium (CRAC) currents in human T lymphocytes |