Neuroactive steroids: A therapeutic approach to maintain peripheral nerve integrity during neurodegenerative events.

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Neuroactive steroids: A therapeutic approach to maintain peripheral nerve integrity during neurodegenerative events. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1008265208
P356DOI10.1385/JMN:28:1:65
P698PubMed publication ID16632876

P50authorRoberto Cosimo MelcangiQ67484798
Valerio MagnaghiQ71190017
P2093author name stringAntonio Consoli
Emanuela Leonelli
Marinella Ballabio
Ilaria Roglio
P2860cites workCharacterization of a novel peripheral nervous system myelin protein (PMP-22/SR13)Q24643599
Peripheral myelin protein 22 and protein zero: a novel association in peripheral nervous system myelinQ28142114
Neurosteroids: pregnenolone in human sciatic nervesQ28316500
Progesterone synthesized by Schwann cells during myelin formation regulates neuronal gene expressionQ28344440
Enhanced expression of the peripheral benzodiazepine receptor (PBR) and its endogenous ligand octadecaneuropeptide (ODN) in the regenerating adult rat sciatic nerveQ28566230
Expression and hormonal regulation of coactivator and corepressor genesQ28568178
Axonal injury-dependent induction of the peripheral benzodiazepine receptor in small-diameter adult rat primary sensory neuronsQ28568802
Retroviral-mediated gene transfer of the peripheral myelin protein PMP22 in Schwann cells: modulation of cell growthQ28576254
Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesisQ28579142
GABAB receptors in Schwann cells influence proliferation and myelin protein expressionQ28583158
Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system.Q33537213
Aging in peripheral nerves: regulation of myelin protein genes by steroid hormones.Q33829615
Myelin synthesis in the peripheral nervous system.Q33869411
Molecular anatomy and genetics of myelin proteins in the peripheral nervous systemQ33880065
Influence of aging on peripheral nerve function and regeneration.Q34127389
SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repairQ34129717
Nongenomically initiated steroid actionsQ34204029
Neurosteroid modulation of GABAA receptorsQ34275980
The action of steroid hormones on peripheral myelin proteins: a possible new tool for the rebuilding of myelin?Q34292720
Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination.Q34319823
Glial cells: a target for steroid hormones.Q34361255
Formation and effects of neuroactive steroids in the central and peripheral nervous system.Q34400453
Preclinical development of neurosteroids as neuroprotective agents for the treatment of neurodegenerative diseasesQ34400492
Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicingQ34633393
Estrogen and ischemic neuroprotection: an integrated viewQ35162545
Disease mechanisms in inherited neuropathiesQ35209953
Steroid hormones and neurosteroids in normal and pathological aging of the nervous system.Q35581317
Aromatase: a neuroprotective enzymeQ35581321
Steroids and the reversal of age-associated changes in myelination and remyelination.Q35581331
Neuroactive steroids influence peripheral myelination: a promising opportunity for preventing or treating age-dependent dysfunctions of peripheral nerves.Q35581336
Neuroprotection by estrogen in animal models of global and focal ischemiaQ35679179
Sex hormones and brain agingQ35974830
Glucocorticoids and progestins signal the initiation and enhance the rate of myelin formationQ37469697
Steroid hormone signaling between Schwann cells and neurons regulates the rate of myelin synthesisQ39677465
SRC-1 is involved in the control of the gene expression of myelin protein Po.Q40509248
Effects of gender and stress on the regulation of steroid receptor coactivator-1 expression in the rat brain and pituitary.Q42513929
Expression and regulation of nuclear receptor coactivators in glucocorticoid actionQ42521900
17Beta-estradiol stimulates regeneration of sciatic nerve in female miceQ44052496
Dehydroepiandrosterone as an enhancer of functional recovery following crush injury to rat sciatic nerveQ44176091
Characterization and regulation of the 3beta-hydroxysteroid dehydrogenase isomerase enzyme in the rat sciatic nerve.Q44251289
Cyclic changes in the expression of steroid receptor coactivators and corepressors in the normal human endometriumQ44306864
Effect of subepineurial dehydroepiandrosterone treatment on healing of transected nerves repaired with the epineurial sleeve techniqueQ44343223
Effect of 17 beta-estradiol on gene expression in lumbar spinal cord following sciatic nerve crush injury in ovariectomized miceQ44368386
ς1Receptor-Related Neuroactive Steroids Modulate Cocaine-Induced RewardQ44433353
Raloxifene analog LY117018 enhances the regeneration of sciatic nerve in ovariectomized female miceQ44514464
Cellular distribution and bioactivity of the key steroidogenic enzyme, cytochrome P450side chain cleavage, in sensory neural pathwaysQ44545150
Progesterone and its derivatives dihydroprogesterone and tetrahydroprogesterone reduce myelin fiber morphological abnormalities and myelin fiber loss in the sciatic nerve of aged rats.Q44555448
Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A).Q44649327
Vestibular Schwann cells are a distinct subpopulation of peripheral glia with specific sensitivity to growth factors and extracellular matrix componentsQ44649526
Estradiol attenuates programmed cell death after stroke-like injury.Q44691577
Downregulation of steroidogenic acute regulatory protein (StAR) gene expression by cyclic AMP in cultured Schwann cells.Q44733682
Mifepristone (RU 38486) influences expression of glycoprotein Po and morphological parameters at the level of rat sciatic nerve: in vivo observations.Q44760150
Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivoQ44763591
Neurotherapeutic action of testosterone on hamster facial nerve regeneration: temporal window of effectsQ44862361
The synthesis of glycoprotein Po and peripheral myelin protein 22 in sciatic nerve of male rats is modulated by testosterone metabolites.Q44945152
Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanoloneQ44945736
Protein zero of peripheral nerve myelin: biosynthesis, membrane insertion, and evidence for homotypic interaction.Q45160252
Ultrastructural analysis of guided nerve regeneration using progesterone- and pregnenolone-loaded chitosan prosthesesQ46406994
Many facets of the peripheral myelin protein PMP22 in myelination and diseaseQ47808553
Immunohistochemical localization of the sigma1 receptor in Schwann cells of rat sciatic nerve.Q47820325
Age-induced decrease of glycoprotein Po and myelin basic protein gene expression in the rat sciatic nerve. Repair by steroid derivativesQ47987337
Regulation of gamma-aminobutyric acidB (GABAB) receptors in cerebral cortex during the estrous cycleQ48155421
Po gene expression is modulated by androgens in the sciatic nerve of adult male rats.Q48178489
Androgen receptor messenger RNA and protein in adult rat sciatic nerve: implications for site of androgen actionQ48494134
Progesterone regulates gamma-aminobutyric acid B (GABAB) receptors in the neocortex of female ratsQ48962809
Demonstration of progesterone receptors in rat Schwann cellsQ49021487
Progesterone derivatives are able to influence peripheral myelin protein 22 and P0 gene expression: possible mechanisms of action.Q51458008
Target influence on aging of myelinated sensory nerve fibres.Q52011066
Regulation of terminal Schwann cell number at the adult neuromuscular junction.Q52172581
Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons.Q52477890
The interaction between neuroactive steroids and the σ1 receptor function: behavioral consequences and therapeutic opportunitiesQ55922778
Neuroactive steroids and peripheral myelin proteinsQ56591723
Detection and processing of peripheral myelin protein PMP22 in cultured Schwann cellsQ57043463
Morphometric and ultrastructural changes with ageing in mouse peripheral nerveQ60681658
Functional changes of the peripheral nervous system with aging in the mouseQ60681674
Progesterone synthesis and myelin formation in peripheral nervesQ60683592
Neurosteroids: Expression of Functional 3β-Hydroxysteroid Dehydrogenase by Rat Sensory Neurons and Schwann CellsQ60683594
Progesterone synthesis and myelin formation by Schwann cellsQ60683596
Modulation of native and recombinant GABAA receptors by endogenous and synthetic neuroactive steroidsQ63488858
Functional abnormalities in P0-deficient mice resemble human hereditary neuropathies linked to P0 gene mutationsQ71394027
Behavioral effects of 3 alpha-androstanediol. I: Modulation of sexual receptivity and promotion of GABA-stimulated chloride fluxQ71710864
Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathiesQ71794009
Coexpression of PMP22 gene with MBP and P0 during de novo myelination and nerve repairQ72097816
Cellular and subcellular localization of AMPA-selective glutamate receptors in the mammalian peripheral vestibular systemQ72186623
The PO glycoprotein of peripheral nerve myelinQ72626535
Heterozygous P0 knockout mice develop a peripheral neuropathy that resembles chronic inflammatory demyelinating polyneuropathy (CIDP)Q73483984
Ion channels in glial cellsQ73666122
Endometrial nuclear receptor co-factors SRC-1 and N-CoR are increased in human endometrium during menstruationQ74373258
Ultrastructural analysis of NMDA, AMPA, and kainate receptors on unmyelinated and myelinated axons in the peripheryQ74399440
Neuroactive steroids: molecular mechanisms of action and implications for neuropsychopharmacologyQ77354244
Neuroprotective effects of gonadal steroids on regenerating peripheral motoneuronsQ77354525
Estrogen and progesterone stimulate Schwann cell proliferation in a sex- and age-dependent mannerQ77974528
Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormonesQ81683799
Peripheral nerves: a target for the action of neuroactive steroidsQ81683812
P433issue1
P921main subjectneurodegenerationQ1755122
P304page(s)65-76
P577publication date2006-01-01
P1433published inJournal of Molecular NeuroscienceQ15708870
P1476titleNeuroactive steroids: A therapeutic approach to maintain peripheral nerve integrity during neurodegenerative events
P478volume28