From touchdown to transcription: the reovirus cell entry pathway

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From touchdown to transcription: the reovirus cell entry pathway is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/82_2010_32
P932PMC publication ID4714703
P698PubMed publication ID20397070
P5875ResearchGate publication ID43161558

P50authorTerence S. DermodyQ87776424
Pranav DanthiQ42084766
Bernardo A MainouQ42351721
P2093author name stringEva Kirchner
Kristen M Guglielmi
Thilo Stehle
P2860cites workViral shedding and transmission between hosts determined by reovirus L2 geneQ70141371
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Reovirus: evidence for a second step in the intracellular uncoating and transcriptase activation processQ70779231
Absolute linkage of virulence and central nervous system cell tropism of reoviruses to viral hemagglutininQ72133339
Mammalian reovirus L2 gene and lambda2 core spike protein sequences and whole-genome comparisons of reoviruses type 1 Lang, type 2 Jones, and type 3 DearingQ74449255
Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loadingQ24328923
Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalinQ24532029
Lysosomal cysteine proteases: facts and opportunitiesQ24535678
Differential sensitivity of normal and transformed human cells to reovirus infectionQ24633362
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigrationQ24682572
Maturation cleavage required for infectivity of a nodavirusQ27486191
A triple beta-spiral in the adenovirus fibre shaft reveals a new structural motif for a fibrous proteinQ27620295
Structure of the reovirus core at 3.6 A resolutionQ27622391
Structure of the reovirus outer capsid and dsRNA-binding protein sigma3 at 1.8 A resolutionQ27630251
Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiberQ27637218
Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3Q27637699
RNA synthesis in a cage--structural studies of reovirus polymerase lambda3Q27640090
Crystal structure of human junctional adhesion molecule 1: Implications for reovirus bindingQ27640992
Reovirus polymerase λ3 localized by cryo-electron microscopy of virions at a resolution of 7.6 ÅQ27642516
The reovirus sigma1 aspartic acid sandwich: a trimerization motif poised for conformational changeQ27643831
Structure of Reovirus σ1 in Complex with Its Receptor Junctional Adhesion Molecule-AQ27653146
Identification and characterisation of human Junctional Adhesion Molecule (JAM)Q28145696
Junction adhesion molecule is a receptor for reovirusQ28203704
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptorQ28254985
Attachment and cell entry of mammalian orthoreovirusQ28257821
Internal/structures containing transcriptase-related proteins in top component particles of mammalian orthoreovirusQ28272793
Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor familyQ28295196
Emerging roles for cysteine proteases in human biologyQ28306260
Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2Q28511801
Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infectionQ28588877
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5Q29616094
Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and diseaseQ29616432
Pathways of chaperone-mediated protein folding in the cytosolQ29618887
Reovirus mu1 structural rearrangements that mediate membrane penetrationQ30159626
Structure of the carboxy-terminal receptor-binding domain of avian reovirus fibre sigmaC.Q30160104
The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture.Q30160264
Structural similarities in the cellular receptors used by adenovirus and reovirusQ30163909
A novel mechanism for the acquisition of virulence by a human influenza A virusQ30431264
Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domainQ33396212
HIV-1 attachment: another look.Q33601938
Cleavage susceptibility of reovirus attachment protein sigma1 during proteolytic disassembly of virions is determined by a sequence polymorphism in the sigma1 neckQ33784880
Reovirus-induced apoptosis requires activation of transcription factor NF-kappaB.Q33800833
Mutant cells selected during persistent reovirus infection do not express mature cathepsin L and do not support reovirus disassembly.Q33823560
Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3.Q33838136
Reovirus binding to cell surface sialic acid potentiates virus-induced apoptosisQ33839080
Identification of carbohydrate-binding domains in the attachment proteins of type 1 and type 3 reovirusesQ33874116
Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and diseaseQ33914633
Type 3 reovirus neuroinvasion after intramuscular inoculation: direct invasion of nerve terminals and age-dependent pathogenesisQ33963215
Adenovirus protein VI mediates membrane disruption following capsid disassembly.Q33984709
Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolutionQ34019963
The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptorsQ34196707
Reovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3.Q34301756
Virion disassembly is required for apoptosis induced by reovirusQ34330619
A single mutation in the carboxy terminus of reovirus outer-capsid protein sigma 3 confers enhanced kinetics of sigma 3 proteolysis, resistance to inhibitors of viral disassembly, and alterations in sigma 3 structureQ34347831
Reovirus therapy of tumors with activated Ras pathwayQ34479740
Genome delivery and ion channel properties are altered in VP4 mutants of poliovirus.Q34976192
Complete in vitro assembly of the reovirus outer capsid produces highly infectious particles suitable for genetic studies of the receptor-binding proteinQ39606223
Sites and determinants of early cleavages in the proteolytic processing pathway of reovirus surface protein sigma3.Q39683392
Strategy for nonenveloped virus entry: a hydrophobic conformer of the reovirus membrane penetration protein micro 1 mediates membrane disruptionQ39684830
Bovine papillomavirus type 1: from clathrin to caveolinQ39766716
Rescue of maturation-defective flock house virus infectivity with noninfectious, mature, viruslike particlesQ40035957
Reovirus M2 gene is associated with chromium release from mouse L cellsQ40046935
Reovirus apoptosis and virulence are regulated by host cell membrane penetration efficiencyQ40062777
Retinoic acid-inducible gene-I and interferon-beta promoter stimulator-1 augment proapoptotic responses following mammalian reovirus infection via interferon regulatory factor-3.Q40125620
Reovirus guanylyltransferase is L2 gene product lambda 2.Q40131290
Reovirus binding determinants in junctional adhesion molecule-A.Q40142387
Reovirus outer capsid protein micro1 induces apoptosis and associates with lipid droplets, endoplasmic reticulum, and mitochondriaQ40243163
A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structureQ40284028
Beta1 integrin mediates internalization of mammalian reovirusQ40311619
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cellsQ40341738
The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry.Q40344603
Endocytosis by random initiation and stabilization of clathrin-coated pitsQ40520631
Putative autocleavage of outer capsid protein micro1, allowing release of myristoylated peptide micro1N during particle uncoating, is critical for cell entry by reovirus.Q40530759
Isolation and molecular characterization of a novel type 3 reovirus from a child with meningitisQ40561414
Cathepsin S supports acid-independent infection by some reovirusesQ40608252
Electron microscopy study of reovirus reaction coresQ40632118
Structure-function analysis of reovirus binding to junctional adhesion molecule 1. Implications for the mechanism of reovirus attachmentQ40635854
Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cellsQ40734800
Oncolytic reovirus against ovarian and colon cancer.Q40742634
Utilization of sialic acid as a coreceptor enhances reovirus attachment by multistep adhesion strengtheningQ40845786
Two Modes of Entry of Reovirus Particles into L CellsQ41031906
Differential interaction of reovirus type 3 with sialylated receptor components on animal cellsQ41465134
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoproteaseQ41505675
Isolation and enzymatic characterization of protein λ2, the reovirus guanylyltransferaseQ41659753
Peptides released from reovirus outer capsid form membrane pores that recruit virus particles.Q41855783
Cathepsin L is involved in proteolytic processing of the Hendra virus fusion proteinQ42042006
A plasmid-based reverse genetics system for animal double-stranded RNA viruses.Q42084718
Junctional adhesion molecule-A is required for hematogenous dissemination of reovirusQ42085912
Complete nucleotide sequence of reovirus L2 gene and deduced amino acid sequence of viral mRNA guanylyltransferase.Q42648183
IkappaB kinase subunits alpha and gamma are required for activation of NF-kappaB and induction of apoptosis by mammalian reovirusQ42957125
JAM-A-independent, antibody-mediated uptake of reovirus into cells leads to apoptosisQ43181943
Reovirus protein lambda 3 is a poly(C)-dependent poly(G) polymeraseQ43576087
Digestion pattern of reovirus outer capsid protein sigma3 determined by mass spectrometryQ43743062
Age dependent susceptibility to Reovirus type 3 encephalitis: role of viral and host factorsQ44434583
Viral RNA Polymerases: Electron Microscopy of Reovirus Reaction CoresQ45000386
Stoichiometry of reovirus structural proteins in virus, ISVP, and core particlesQ45756975
Genetics of reovirus: identification of the ds RNA segments encoding the polypeptides of the mu and sigma size classesQ47316030
Binding site for S-adenosyl-L-methionine in a central region of mammalian reovirus lambda2 protein. Evidence for activities in mRNA cap methylation.Q52565526
Prevalence of Reovirus‐Specific Antibodies in Young Children in Nashville, TennesseeQ56481070
The mechanisms of reovirus uncoating and gene activation in vivoQ67294193
The nature of the polypeptide encoded by each of the 10 double-stranded RNA segments of reovirus type 3Q67412668
Mechanism of formation of reovirus mRNA 5'-terminal blocked and methylated sequence, m7GpppGmpCQ67525409
Biochemical and biophysical characterization of the reovirus cell attachment protein sigma 1: evidence that it is a homotrimerQ67944238
Active site localization in a viral mRNA capping enzymeQ68457689
Effect of neuraminidase treatment of cells and effect of soluble glycoproteins on type 3 reovirus attachment to murine L cellsQ36852462
Intracellular digestion of reovirus particles requires a low pH and is an essential step in the viral infectious cycle.Q36915422
Activation and characterization of the reovirus transcriptase: genetic analysisQ36936630
Direct spread of reovirus from the intestinal lumen to the central nervous system through vagal autonomic nerve fibersQ37500830
Identification of the guanylyltransferase region and active site in reovirus mRNA capping protein lambda2.Q38316274
Junctional adhesion molecule a serves as a receptor for prototype and field-isolate strains of mammalian reovirusQ38324922
The alpha-anomeric form of sialic acid is the minimal receptor determinant recognized by reovirusQ38343681
Flexibility of the adenovirus fiber is required for efficient receptor interactionQ38353615
Identification of an NF-kappaB-dependent gene network in cells infected by mammalian reovirus.Q38519145
Reovirus virion-like particles obtained by recoating infectious subvirion particles with baculovirus-expressed sigma3 protein: an approach for analyzing sigma3 functions during virus entry.Q39549886
In vitro recoating of reovirus cores with baculovirus-expressed outer-capsid proteins mu1 and sigma3.Q39550452
Protease cleavage of reovirus capsid protein mu1/mu1C is blocked by alkyl sulfate detergents, yielding a new type of infectious subvirion particle.Q39577260
Molecular basis of reovirus virulence: Role of the S1 geneQ35054361
Structural evidence for common functions and ancestry of the reovirus and adenovirus attachment proteinsQ35081788
Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary diseaseQ35095524
Invasion of host cells by JC virus identifies a novel role for caveolae in endosomal sorting of noncaveolar ligandsQ35101449
The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfacesQ35104539
Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane.Q35133892
Binding of type 3 reovirus by a domain of the sigma 1 protein important for hemagglutination leads to infection of murine erythroleukemia cellsQ35614021
Infectious subvirion particles of reovirus type 3 Dearing exhibit a loss in infectivity and contain a cleaved sigma 1 proteinQ35845209
Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein sigma 1Q35850820
Role of the mu 1 protein in reovirus stability and capacity to cause chromium release from host cells.Q35853771
Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genesQ35872484
Reovirus variants selected during persistent infections of L cells contain mutations in the viral S1 and S4 genes and are altered in viral disassemblyQ35877228
Mutations in type 3 reovirus that determine binding to sialic acid are contained in the fibrous tail domain of viral attachment protein sigma1.Q35877813
Thermostabilizing mutations in reovirus outer-capsid protein mu1 selected by heat inactivation of infectious subvirion particlesQ35879120
Mutations in reovirus outer-capsid protein sigma3 selected during persistent infections of L cells confer resistance to protease inhibitor E64Q35887561
Glycoconjugate glycans as viral receptorsQ36194868
Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 bindingQ36230268
Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: analysis of virions and subviral particles by cryoelectron microscopy and image reconstructionQ36232691
Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected miceQ36399901
NPXY motifs in the beta1 integrin cytoplasmic tail are required for functional reovirus entryQ36498196
Drug evaluation: Reolysin--wild-type reovirus as a cancer therapeutic.Q36506689
Proteolytic processing of reovirus is required for adherence to intestinal M cellsQ36638339
Isolation and genetic characterization of ethanol-resistant reovirus mutantsQ36644956
Ion channels induced in lipid bilayers by subvirion particles of the nonenveloped mammalian reovirusesQ36660165
A carboxy-terminal fragment of protein mu 1/mu 1C is present in infectious subvirion particles of mammalian reoviruses and is proposed to have a role in penetrationQ36684993
Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses.Q36686120
A role for molecular chaperone Hsc70 in reovirus outer capsid disassemblyQ36769116
A sigma 1 region important for hemagglutination by serotype 3 reovirus strainsQ36784412
A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetrationQ36802470
Intraluminal proteolytic activation plays an important role in replication of type 1 reovirus in the intestines of neonatal miceQ36804334
Structure of the reovirus cell-attachment protein: a model for the domain organization of sigma 1.Q36808171
Molecular structure of the cell-attachment protein of reovirus: correlation of computer-processed electron micrographs with sequence-based predictionsQ36808217
Sigma 1 protein of mammalian reoviruses extends from the surfaces of viral particlesQ36826294
Proteolytic digestion of reovirus in the intestinal lumens of neonatal miceQ36831570
P921main subjectReovirusQ69812835
P304page(s)91-119
P577publication date2010-01-01
P1433published inCurrent Topics in Microbiology and ImmunologyQ15752446
P1476titleFrom touchdown to transcription: the reovirus cell entry pathway
P478volume343

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