Alloantigen-induced unresponsiveness in cord blood T lymphocytes is associated with defective activation of Ras.

scientific article

Alloantigen-induced unresponsiveness in cord blood T lymphocytes is associated with defective activation of Ras. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1998PNAS...95.4538P
P356DOI10.1073/PNAS.95.8.4538
P932PMC publication ID22525
P698PubMed publication ID9539773
P5875ResearchGate publication ID51331720

P50authorHal E. BroxmeyerQ51754776
P2093author name stringP Porcu
J Gaddy
P2860cites workp56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulationQ24311999
Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP)Q24336881
Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cellsQ24680080
Diminished expression of CD40 ligand by activated neonatal T cellsQ34192818
Alloantigen priming induces a state of unresponsiveness in human umbilical cord blood T cellsQ34596608
Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathwaysQ34882263
Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulationQ36367209
Graft-versus-host disease: host and donor views.Q40812188
T cell antigen receptor signal transduction pathwaysQ41039700
CD28: a signalling perspective.Q41113501
CD28 delivers costimulatory signals independently of its association with phosphatidylinositol 3-kinaseQ41270812
The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune responseQ41332070
Phosphatidylinositol 3-kinase activity is not essential for CD28 costimulatory activity in Jurkat T cells: studies with a selective inhibitor, wortmanninQ41371599
T cell antigen receptor signal transductionQ41382861
Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptorQ41429389
Expression of the interleukin-2 receptor gamma chain on cord blood mononuclear cells.Q42628389
Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host diseaseQ45232862
Activation antigen expression on human T cells. I. Analysis by two-colour flow cytometry of umbilical cord blood, adult blood and lymphoid tissue.Q51113016
CD40 ligand is expressed and functional on activated neonatal T cells.Q52050410
In vitro cytokine production and phenotype expression by blood mononuclear cells from umbilical cords, children and adults.Q54583458
Stimulation of p21 ras upon T-cell activationQ57903895
Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T CellsQ58882241
A cell culture model for T lymphocyte clonal anergyQ67299314
Calcium ionophore plus phorbol ester can substitute for antigen in the induction of cytolytic T lymphocytes from specifically primed precursorsQ68940699
Blocked Ras activation in anergic CD4+ T cellsQ71095980
Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipientsQ71133353
A novel single-cell proliferation assay shows that long-term culture-initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-ICQ72030920
Proliferative and cytotoxic responses of human cord blood T lymphocytes following allogeneic stimulationQ72269722
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)4538-4543
P577publication date1998-04-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAlloantigen-induced unresponsiveness in cord blood T lymphocytes is associated with defective activation of Ras.
P478volume95

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cites work (P2860)
Q79207389A comparison of ex vivo expanded DCs derived from cord blood and mobilized adult peripheral blood plastic-adherent mononuclear cells: decreased alloreactivity of cord blood DCs
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Q44606441Association of CD26 with CD45RA outside lipid rafts attenuates cord blood T-cell activation
Q43662440Cyclosporin A effects during primary and secondary activation of human umbilical cord blood T lymphocytes
Q44583955Distinctive response of naïve lymphocytes from cord blood to primary activation via TCR.
Q44729731Estrogen decreases expression of chemokine receptors, and suppresses chemokine bioactivity in murine monocytes
Q34302303HIV delays IFN-α production from human plasmacytoid dendritic cells and is associated with SYK phosphorylation
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