| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | K. Beyreuther | |
| C. L. Masters | |||
| P2860 | cites work | Expression of beta-amyloid precursor protein in reactive astrocytes following neuronal damage | Q69282065 |
| Three types of amyloid protein precursor mRNA in human brain: their differential expression in Alzheimer's disease | Q70414479 | ||
| Immunoreactive epidermal growth factor receptors in neuritic plaques from patients with Alzheimer's disease. | Q53303541 | ||
| Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch) | Q57849311 | ||
| Immunocytochemical localization of the precursor protein for beta-amyloid in the rat central nervous system | Q67260747 | ||
| Platelet coagulation factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein | Q67292492 | ||
| Synthesis and secretion of Alzheimer amyloid beta A4 precursor protein by stimulated human peripheral blood leucocytes | Q68372750 | ||
| Modification of neuronal cell adhesion affects the genetic expression of the A4 amyloid peptide precursor | Q69074828 | ||
| Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides | Q22242269 | ||
| Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's disease | Q24322567 | ||
| Amyloid plaque core protein in Alzheimer disease and Down syndrome | Q24568384 | ||
| Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease | Q28241772 | ||
| Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein | Q29547803 | ||
| The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor | Q29618322 | ||
| Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites. | Q33298909 | ||
| Formation of amyloid-like fibrils in COS cells overexpressing part of the Alzheimer amyloid protein precursor | Q33505498 | ||
| In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease | Q33554297 | ||
| Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer disease | Q33554847 | ||
| Distribution of precursor amyloid-beta-protein messenger RNA in human cerebral cortex: relationship to neurofibrillary tangles and neuritic plaques. | Q33558559 | ||
| Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid, and lesioned mice | Q33575703 | ||
| Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease | Q33593817 | ||
| Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease | Q33594005 | ||
| Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues. | Q33652573 | ||
| Differences between vascular and plaque core amyloid in Alzheimer's disease | Q34172702 | ||
| The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid | Q34298069 | ||
| Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease | Q34415666 | ||
| Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type | Q48265529 | ||
| Structure and expression of the alternatively-spliced forms of mRNA for the mouse homolog of Alzheimer's disease amyloid beta protein precursor | Q48304073 | ||
| Laminar distribution of neocortical senile plaques in senile dementia of the Alzheimer type | Q48396805 | ||
| Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimer's disease | Q48448130 | ||
| Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease | Q48770682 | ||
| Alzheimer A4 peptide, gamma-trace, leukoencephalopathy, and hereditary cerebral hemorrhage with amyloidosis-Dutch type | Q48774140 | ||
| Memory-related neural systems in Alzheimer's disease: an anatomic study | Q48866916 | ||
| The amyloid beta-protein precursor is localized in smooth muscle cells of leptomeningeal vessels | Q48879554 | ||
| Alzheimer's disease amyloid precursor protein is present in the myelin sheath of central nervous system in rat. | Q48897928 | ||
| Intraventricular infusions of antibodies to amyloid-beta-protein precursor impair the acquisition of a passive avoidance response in the rat. | Q48932605 | ||
| Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study | Q49090173 | ||
| Differential splicing of Alzheimer's disease amyloid A4 precursor RNA in rat tissues: PreA4(695) mRNA is predominantly produced in rat and human brain | Q49100289 | ||
| The binding of basic fibroblast growth factor to Alzheimer's neurofibrillary tangles and senile plaques | Q53181497 | ||
| Alternative splicing of the βA4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients | Q53182592 | ||
| Alzheimer's mutation. | Q53182897 | ||
| The temporal expression of amyloid precursor protein mRNA in vitro in dissociated hippocampal neuron cultures. | Q53184494 | ||
| Alzheimer cortical neurons containing abundant amyloid mRNA. Relationship to amyloid deposition and senile plaques. | Q53185026 | ||
| Identification of beta protein precursor in newborn rat brain. | Q53186957 | ||
| Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain. | Q53187068 | ||
| Expression and cellular localization of amyloid beta-protein precursor transcripts in normal human brain and in Alzheimer's disease. | Q53187075 | ||
| Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. | Q53187594 | ||
| Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. | Q53188216 | ||
| A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition. | Q53188363 | ||
| The genetic defect causing familial Alzheimer's disease maps on chromosome 21. | Q53189946 | ||
| Expression of the Alzheimer amyloid precursor gene transcripts in the human brain. | Q53190283 | ||
| A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques. | Q53191092 | ||
| Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimer's disease. | Q53192317 | ||
| The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects. | Q53300850 | ||
| Ubiquitin is a component of paired helical filaments in Alzheimer's disease. | Q53303482 | ||
| Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence | Q34610715 | ||
| A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein | Q35564226 | ||
| Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease | Q35980016 | ||
| Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease | Q36415791 | ||
| Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity | Q36415795 | ||
| Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease | Q36443496 | ||
| Amyloid precursor protein in aged nonhuman primates | Q37406618 | ||
| Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease | Q37546301 | ||
| Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles. | Q37580789 | ||
| Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport | Q37701379 | ||
| Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats | Q37739715 | ||
| Stimulated platelets release amyloid beta-protein precursor | Q39544512 | ||
| Regulatory region of human amyloid precursor protein (APP) gene promotes neuron-specific gene expression in the CNS of transgenic mice. | Q41079778 | ||
| Immunochemical evidence that fragments of phosphorylated MAP5 (MAP1B) are bound to neurofibrillary tangles in Alzheimer's disease | Q41233680 | ||
| Selective reduction of mRNA for the beta-amyloid precursor protein that lacks a Kunitz-type protease inhibitor motif in cortex from Alzheimer brains | Q41254290 | ||
| A4 amyloid protein immunoreactivity is present in Alzheimer's disease neurofibrillary tangles | Q41296324 | ||
| Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion | Q41709571 | ||
| Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern | Q41722059 | ||
| Neural differentiation increases expression of Alzheimer amyloid protein precursor gene in murine embryonal carcinoma cells | Q41724416 | ||
| Amyloid beta-protein precursor is associated with extracellular matrix | Q41734461 | ||
| Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR. | Q41746563 | ||
| The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion | Q41760569 | ||
| Cleavage of amyloid beta peptide during constitutive processing of its precursor | Q41852594 | ||
| Immuno-electron microscopic localization of immunoglobulins in amyloid fibrils of senile plaques | Q41982458 | ||
| Amyloid beta protein precursor is a mitogen | Q42797602 | ||
| In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells | Q43466393 | ||
| The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II. | Q43466747 | ||
| Accumulation of amyloid precursor fragment in Alzheimer plaques | Q43713988 | ||
| Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein | Q43776532 | ||
| Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices | Q44032224 | ||
| Amyloid beta protein enhances the survival of hippocampal neurons in vitro | Q44109304 | ||
| Amyloid in the brains of aged squirrel monkeys | Q44170096 | ||
| Developmental and differential expression of beta amyloid protein precursor mRNAs in mouse brain | Q44236384 | ||
| Expression of the genes for transthyretin, cystatin C and beta A4 amyloid precursor protein in sheep choroid plexus during development | Q44246951 | ||
| Neurofibrillary changes confined to the entorhinal region and an abundance of cortical amyloid in cases of presenile and senile dementia | Q44283048 | ||
| The Alzheimer's amyloid precursor protein is produced by type I astrocytes in primary cultures of rat neuroglia | Q44289916 | ||
| Amyloid beta-protein deposition in tissues other than brain in Alzheimer's disease | Q45039020 | ||
| Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing | Q45039717 | ||
| Intact Alzheimer amyloid precursor protein (APP) is present in platelet membranes and is encoded by platelet mRNA. | Q45125893 | ||
| Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts. | Q45966280 | ||
| Decreased adhesiveness of Alzheimer's disease fibroblasts: is amyloid beta-protein precursor involved? | Q45990148 | ||
| A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors | Q46046983 | ||
| Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease | Q46121331 | ||
| Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage | Q46135113 | ||
| Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor | Q46359315 | ||
| Beta-amyloid protein promotes neuritic branching in hippocampal cultures | Q46788539 | ||
| Ubiquitin-protein conjugates in Alzheimer's lesions | Q46858168 | ||
| Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor | Q47070911 | ||
| A variety of cerebral amyloid deposits in the brains of the Alzheimer-type dementia demonstrated by beta protein immunostaining | Q48156275 | ||
| Cholinesterases within neurofibrillary tangles related to age and Alzheimer's disease | Q48222617 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Alzheimer's disease | Q11081 |
| P304 | page(s) | 241-251 | |
| P577 | publication date | 1991-07-01 | |
| P1433 | published in | Brain Pathology | Q4955776 |
| P1476 | title | Amyloid precursor protein (APP) and beta A4 amyloid in the etiology of Alzheimer's disease: precursor-product relationships in the derangement of neuronal function | |
| Amyloid Precursor Protein (APP) and ΒZA4 Amyloid in the Etiology of Alzheimer's Disease: Precursor-Product Relationships in the Derangement of Neuronal Function | |||
| P478 | volume | 1 |
| Q90893924 | A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease |
| Q55322228 | A discrete mathematical model for the aggregation of β-Amyloid. |
| Q48326013 | A grading system of Alzheimer disease lesions in neocortical areas |
| Q90580004 | AD "Statin": Alzheimer's Disorder is a "Fast" Disease Preventable by Therapeutic Intervention Initiated Even Late in Life and Reversible at the Early Stages |
| Q23923132 | Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path |
| Q89841160 | Alzheimer's disease pathology in APOE transgenic mouse models: The Who, What, When, Where, Why, and How |
| Q70913702 | Amyloid precursor protein (APP) expression in multiple sclerosis lesions |
| Q34229659 | Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3 |
| Q53221111 | Apolipoprotein E epsilon 4 allele distribution in Wernicke-Korsakoff syndrome with or without global intellectual deficits. |
| Q42987047 | Apolipoprotein E forms stable complexes with recombinant Alzheimer's disease beta-amyloid precursor protein |
| Q22248076 | Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease |
| Q34680878 | Apolipoproteins in the brain: implications for neurological and psychiatric disorders |
| Q93152965 | BACE1 Translation: At the Crossroads Between Alzheimer's Disease Neurodegeneration and Memory Consolidation |
| Q57174872 | Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer's Disease? |
| Q47985863 | Capsaicin Attenuates Amyloid-β-Induced Synapse Loss and Cognitive Impairments in Mice |
| Q41639782 | Cerebral vessels in ageing and Alzheimer's disease |
| Q57306417 | Chapter 3 Structural Changes in the Aged Brain |
| Q92450851 | Clinical trials of new drugs for Alzheimer disease |
| Q48223946 | Cytological demonstration of features of Alzheimer's disease using brain smear technique. |
| Q37068771 | Development and evaluation of compounds for imaging of beta-amyloid plaque by means of positron emission tomography |
| Q42475459 | Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia. |
| Q53782183 | Effect of aging on neurogenesis in the canine brain. |
| Q38488284 | Electron microscopic study of paired helical filaments and cerebral amyloid using a novel en bloc silver staining method |
| Q73074470 | Expression of beta-amyloid precursor and Bcl-2 proto-oncogene proteins in rat retinas after intravitreal injection of aminoadipic acid |
| Q72333929 | Glial expression of the beta-amyloid precursor protein (APP) in global ischemia |
| Q71819572 | Inflammatory reaction in experimental autoimmune encephalomyelitis (EAE) is accompanied by a microglial expression of the βA4‐amyloid precursor protein (APP) |
| Q43852858 | Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate |
| Q35592172 | Molecular biology of Alzheimer's amyloid--Dutch variant |
| Q41579457 | Monomer-dependent secondary nucleation in amyloid formation |
| Q39144600 | Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support. |
| Q46272723 | Oxidative stress and the amyloid beta peptide in Alzheimer's disease |
| Q37617386 | Plasma Exosomes Spread and Cluster Around β-Amyloid Plaques in an Animal Model of Alzheimer's Disease. |
| Q34394248 | Platelet amyloid precursor protein forms in AD: a peripheral diagnostic tool and a pharmacological target. |
| Q92135579 | Precursor-Independent Overproduction of Beta-Amyloid in AD: Mitochondrial Dysfunction as Possible Initiator of Asymmetric RNA-Dependent βAPP mRNA Amplification. An Engine that Drives Alzheimer's Disease |
| Q90172885 | Protein-Encoding RNA-to-RNA Information Transfer in Mammalian Cells: Principles of RNA-Dependent mRNA Amplification |
| Q40379335 | Reactive microglia in cerebral ischaemia: an early mediator of tissue damage? |
| Q55428413 | Results of Beta Secretase-Inhibitor Clinical Trials Support Amyloid Precursor Protein-Independent Generation of Beta Amyloid in Sporadic Alzheimer's Disease. |
| Q58754323 | Role of Microbes in the Development of Alzheimer's Disease: State of the Art - An International Symposium Presented at the 2017 IAGG Congress in San Francisco |
| Q40782240 | Subacute spongiform encephalopathies--the transmissible brain amyloidoses: a comparison with the non-transmissible brain amyloidoses of Alzheimer type |
| Q89313421 | Super-resolution Imaging of Amyloid Structures over Extended Times by Using Transient Binding of Single Thioflavin T Molecules |
| Q89726182 | TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer's disease |
| Q26749528 | The amyloid hypothesis of Alzheimer's disease at 25 years |
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| Q40392468 | Transmissible cerebral amyloidoses as a model for Alzheimer's disease. An ultrastructural perspective |
| Q37378620 | Yi-Zhi-Fang-Dai Formula Protects against Aβ1-42 Oligomer Induced Cell Damage via Increasing Hsp70 and Grp78 Expression in SH-SY5Y Cells |
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