Nonchimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers

scientific article

Nonchimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/AJT.13416
P932PMC publication ID4718825
P698PubMed publication ID26227106
P5875ResearchGate publication ID280583567

P50authorJohn J FriedewaldQ42686679
Sunil M KurianQ46181458
Daniel R. SalomonQ112670906
P2093author name stringJ Miller
L Gallon
Y S Kanwar
J Levitsky
M M Abecassis
A R Tambur
J R Leventhal
J Charette
C Jie
J M Mathew
I Konieczna
P2860cites workImmunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanismsQ33195020
HLA-mismatched renal transplantation without maintenance immunosuppressionQ33640791
Immune "tolerance profiles" in donor bone marrow infused kidney transplant patients using multiple ex vivo functional assaysQ33867234
Identification of a B cell signature associated with renal transplant tolerance in humans.Q33882845
Defining the alloreactive T cell repertoire using high-throughput sequencing of mixed lymphocyte reaction cultureQ34446000
Mixed Chimerism, Lymphocyte Recovery, and Evidence for Early Donor-Specific Unresponsiveness in Patients Receiving Combined Kidney and Bone Marrow Transplantation to Induce ToleranceQ34691385
Tolerance associated gene expression following allogeneic hematopoietic cell transplantationQ35182401
Immune responses and their regulation by donor bone marrow cells in clinical organ transplantationQ35216479
Renal transplantation between HL-A identical donor-recipient pairs. Functional and morphological evaluationQ35898871
Depletion of foxp3(+) T cells abrogates tolerance of skin and heart allografts in murine mixed chimeras without the loss of mixed chimerismQ35911438
Tolerance and withdrawal of immunosuppressive drugs in patients given kidney and hematopoietic cell transplantsQ35918706
Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft toleranceQ36024233
Tolerance induction in HLA disparate living donor kidney transplantation by donor stem cell infusion: durable chimerism predicts outcomeQ36492262
Chimerism and tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantationQ36722979
Genomic biomarkers correlate with HLA-identical renal transplant toleranceQ37119938
Human CD8+ T-regulatory cells with low-avidity T-cell receptor specific for minor histocompatibility antigensQ37149887
Calcineurin inhibitors in HLA-identical living related donor kidney transplantationQ37464226
Tolerance and chimerism after renal and hematopoietic-cell transplantationQ40428891
Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabineQ42028666
The human "Treg MLR": immune monitoring for FOXP3+ T regulatory cell generation.Q42954783
T-cell reactivity during tapering of immunosuppression to low-dose monotherapy prednisolone in HLA-identical living-related renal transplant recipientsQ46081831
Successful tapering of immunosuppression to low-dose monotherapy steroids after living-related human leukocyte antigen-identical renal transplantationQ46084204
Regulatory T-cells in the graft and the risk of acute graft-versus-host disease after allogeneic stem cell transplantation.Q53557826
Donor bone marrow-derived chimeric cells present in renal transplant recipients infused with donor marrow. I. Potent regulators of recipient antidonor immune responsesQ73383278
Involvement of multiple subpopulations of human bone marrow cells in the regulation of allogeneic cellular immune responsesQ73383293
Cellular immune responses of human cadaver donor bone marrow cells and their susceptibility to commonly used immunosuppressive drugs in transplantationQ74494006
In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigensQ77859052
Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerismQ78237930
FoxP3 mRNA transcripts and regulatory cells in renal transplant recipients 10 years after donor marrow infusionQ80521452
Chimerism, graft survival, and withdrawal of immunosuppressive drugs in HLA matched and mismatched patients after living donor kidney and hematopoietic cell transplantationQ86763876
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
P304page(s)221-234
P577publication date2015-07-30
P1433published inAmerican Journal of TransplantationQ4744273
P1476titleNonchimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers
P478volume16

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cites work (P2860)
Q54216691A Phase I Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants.
Q53475944A composite score associated with spontaneous operational tolerance in kidney transplant recipients.
Q57143685Biomarkers and Pharmacogenomics in Kidney Transplantation
Q33842783Biomarkers in renal transplantation: An updated review
Q37462039Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?
Q38754342Cell therapeutic approaches to immunosuppression after clinical kidney transplantation
Q39215677Chimerism-based tolerance in organ transplantation: preclinical and clinical studies.
Q50145136Cyclophosphamide-induced tolerance in kidney transplantation avoids long-term immunosuppressive therapy
Q64982406Early expansion of donor-specific Tregs in tolerant kidney transplant recipients.
Q48215037Generation and Characterization of Alloantigen-Specific Regulatory T Cells For Clinical Transplant Tolerance
Q38935186Hematopoietic stem cells and solid organ transplantation
Q38793766Immune monitoring in renal transplantation: The search for biomarkers
Q45074422Intragraft Molecular Pathways Associated with Tolerance Induction in Renal Transplantation.
Q55450034Long-Term Clinical and Immunological Profile of Kidney Transplant Patients Given Mesenchymal Stromal Cell Immunotherapy.
Q42368320Rapamycin is highly effective in murine models of immune-mediated bone marrow failure
Q41444299Recent Progress in Cell Therapy in Solid Organ Transplantation
Q61805676Transient increase of activated regulatory T cells early after kidney transplantation
Q26751022Transplantation Tolerance Induction: Cell Therapies and Their Mechanisms
Q50164418Updated Follow-Up of a Tolerance Protocol in HLA-identical Renal Transplant Pairs Given Donor Hematopoietic Stem Cells.
Q47822802Using omics to explore complications of kidney transplantation.

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