Binding of hanatoxin to the voltage sensor of Kv2.1.

scientific article

Binding of hanatoxin to the voltage sensor of Kv2.1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/TOXINS4121552
P932PMC publication ID3528262
P698PubMed publication ID23250329
P5875ResearchGate publication ID233949006

P2093author name stringRong Chen
Shin-Ho Chung
Anna Robinson
P2860cites workPortability of paddle motif function and pharmacology in voltage sensorsQ24649968
Interactions between lipids and voltage sensor paddles detected with tarantula toxinsQ24650954
Effects of phrixotoxins on the Kv4 family of potassium channels and implications for the role of Ito1 in cardiac electrogenesisQ24672433
SWISS-MODEL: An automated protein homology-modeling serverQ24672647
Tarantula toxins interact with voltage sensors within lipid membranesQ24684404
Comparison of simple potential functions for simulating liquid waterQ26778447
Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxinsQ27621843
Solution structure and functional characterization of SGTx1, a modifier of Kv2.1 channel gatingQ27643031
Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinementQ27662142
All-atom empirical potential for molecular modeling and dynamics studies of proteinsQ27860468
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The SWISS-MODEL workspace: a web-based environment for protein structure homology modellingQ27860637
Scalable molecular dynamics with NAMDQ27860718
Close-range electrostatic interactions in proteinsQ28204004
Crystal structure of a mammalian voltage-dependent Shaker family K+ channelQ28260421
Heteropodatoxins: peptides isolated from spider venom that block Kv4.2 potassium channelsQ28580698
Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanesQ29397708
Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulationsQ29547631
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Update of the CHARMM all-atom additive force field for lipids: validation on six lipid typesQ29616710
Utility of homology models in the drug discovery process.Q30342415
Isolation, amino acid sequence and functional assays of SGTx1. The first toxin purified from the venom of the spider scodra griseipesQ30781717
Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channelQ30987422
Functional analysis of an archaebacterial voltage-dependent K+ channelQ34182941
An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean tarantulaQ34296892
Integrating statistical pair potentials into protein complex prediction.Q51626110
Common features in the functional surface of scorpion beta-toxins and elements that confer specificity for insect and mammalian voltage-gated sodium channels.Q51821558
Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels.Q52553006
Binding modes and functional surface of anti-mammalian scorpion α-toxins to sodium channels.Q52743675
The cystine knot structure of ion channel toxins and related polypeptidesQ77476305
Vstx1, a modifier of Kv channel gating, localizes to the interfacial region of lipid bilayersQ79141153
Localization of the voltage-sensor toxin receptor on KvAPQ80405335
Interaction between K+ channel gate modifier hanatoxin and lipid bilayer membranes analyzed by molecular dynamics simulationQ82448612
A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venomQ34331989
Heteropoda toxin 2 is a gating modifier toxin specific for voltage-gated K+ channels of the Kv4 familyQ34398021
Voltage-sensor activation with a tarantula toxin as cargo.Q34442179
Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II.Q34479240
Tarantula toxins interacting with voltage sensors in potassium channelsQ34580857
Is lipid bilayer binding a common property of inhibitor cysteine knot ion-channel blockers?Q35906168
Molecular surface of tarantula toxins interacting with voltage sensors in K(v) channelsQ36412562
Helical structure of the COOH terminus of S3 and its contribution to the gating modifier toxin receptor in voltage-gated ion channelsQ36427232
Localization and molecular determinants of the Hanatoxin receptors on the voltage-sensing domains of a K(+) channelQ36442884
Exploring conformational states of the bacterial voltage-gated sodium channel NavAb via molecular dynamics simulationsQ36504362
Structural dynamics of an isolated voltage-sensor domain in a lipid bilayerQ37244466
Interactions between a voltage sensor and a toxin via multiscale simulations.Q40072089
SGTx1, a Kv channel gating-modifier toxin, binds to the interfacial region of lipid bilayersQ41046582
Closing in on the resting state of the Shaker K(+) channel.Q42633636
Mechanism of voltage gating in potassium channelsQ42644041
Conserved functional surface of antimammalian scorpion β-toxinsQ44096067
Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sitesQ48960054
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P304page(s)1552-1564
P577publication date2012-12-18
P1433published inToxinsQ15724569
P1476titleBinding of hanatoxin to the voltage sensor of Kv2.1.
P478volume4

Reverse relations

cites work (P2860)
Q26775013Computational Studies of Venom Peptides Targeting Potassium Channels
Q47267039Defective trafficking of Kv2.1 channels in MPTP-induced nigrostriatal degeneration.
Q33728861Oxidation of KCNB1 K(+) channels in central nervous system and beyond

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