| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.3727/000000006783982007 |
| P698 | PubMed publication ID | 16719061 |
| P2093 | author name string | Howard J Federoff | |
| Carolyn M Tyler | |||
| P2860 | cites work | Nerve growth factor regulation of choline acetyltransferase gene expression in rat embryo basal forebrain cultures | Q43486481 |
| Selective antibody-induced cholinergic cell and synapse loss produce sustained hippocampal and cortical hypometabolism with correlated cognitive deficits | Q43649910 | ||
| Impaired axonal transport of cortical neurons in Alzheimer's disease is associated with neuropathological changes | Q44182588 | ||
| Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75. | Q44230519 | ||
| A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease | Q45883058 | ||
| Morphological response of axotomized septal neurons to nerve growth factor | Q46247799 | ||
| Somatic gene transfer to the adult primate central nervous system:in vitroandin vivocharacterization of cells genetically modified to secrete nerve growth factor | Q46382960 | ||
| Differential vesicular targeting and time course of synaptic secretion of the mammalian neurotrophins. | Q46656538 | ||
| Gene-environment interaction in Alzheimer's disease: a potential role for cholesterol | Q47680921 | ||
| Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease | Q47695139 | ||
| SNAP-25 and syntaxin, but not synaptobrevin 2, cooperate in the regulated release of nerve growth factor | Q47839807 | ||
| Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor | Q48208108 | ||
| Primate nucleus basalis of Meynert p75NGFR-containing cholinergic neurons are protected from retrograde degeneration by the ganglioside GM1. | Q48322365 | ||
| Choline acetyltransferase messenger RNA expression in developing and adult rat brain: regulation by nerve growth factor | Q48792435 | ||
| Localization of cellular storage compartments and sites of constitutive and activity-dependent release of nerve growth factor (NGF) in primary cultures of hippocampal neurons | Q49092302 | ||
| Induction of cell death by endogenous nerve growth factor through its p75 receptor | Q58047180 | ||
| Sortilin is essential for proNGF-induced neuronal cell death | Q24312692 | ||
| Lentiviral gene delivery of GDNF into the striatum of R6/2 Huntington mice fails to attenuate behavioral and neuropathological changes | Q31158487 | ||
| On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis | Q33421837 | ||
| Cholinesterase inhibitors: a therapeutic strategy for Alzheimer disease | Q33637687 | ||
| Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model | Q34105795 | ||
| Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation | Q34113268 | ||
| The neurotrophin hypothesis for synaptic plasticity. | Q34117599 | ||
| ProNGF: a neurotrophic or an apoptotic molecule? | Q34286971 | ||
| The aging brain: morphomolecular senescence of cortical circuits | Q34349216 | ||
| The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death | Q34457074 | ||
| Neurotrophin secretory pathways and synaptic plasticity | Q35595447 | ||
| Apolipoprotein gene and its interaction with the environmentally driven risk factors: molecular, genetic and epidemiological studies of Alzheimer's disease | Q35789666 | ||
| Molecular pathways to neurodegeneration | Q35844771 | ||
| The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor | Q35884401 | ||
| Illustration of dynamic changes in Alzheimer pathology: from mild cognitive impairment to terminal stage | Q36355470 | ||
| Infusion of nerve growth factor (NGF) into kitten visual cortex increases immunoreactivity for NGF, NGF receptors, and choline acetyltransferase in basal forebrain without affecting ocular dominance plasticity or column development | Q36755096 | ||
| Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury | Q37647649 | ||
| Specificity of retrograde transport of nerve growth factor (NGF) in sensory neurons: A biochemical and morphological study | Q39336204 | ||
| Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector | Q40329807 | ||
| A combination of mutations enhances the neurotropism of AAV-2. | Q40384910 | ||
| Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus | Q40483395 | ||
| Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons | Q40636683 | ||
| Recent advances in the genetics of Alzheimer's disease and vascular dementia with an emphasis on gene-environment interactions | Q41150751 | ||
| Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75. | Q41204589 | ||
| Neurotrophins live or let die: does p75NTR decide? | Q41366415 | ||
| Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons | Q41433192 | ||
| Nerve growth factor signaling in caveolae-like domains at the plasma membrane | Q41706850 | ||
| Expression of messenger RNA coding for the nerve growth factor receptor trkA in the hippocampus of the adult rat. | Q42435025 | ||
| Cholinergic neuropathology in a mouse model of Alzheimer's disease | Q42443172 | ||
| Frequency of stages of Alzheimer-related lesions in different age categories | Q42445469 | ||
| Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat. | Q42449707 | ||
| The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons | Q42454315 | ||
| NGF-induction of the expression of ChAT mRNA in PC12 cells and primary cultures of embryonic rat basal forebrain. | Q42463229 | ||
| Molecular mechanisms regulating NGF-mediated enhancement of cholinergic neuronal phenotype: c-fos trans-activation of the choline acetyltransferase gene | Q42464415 | ||
| Characterization of Nerve Growth Factor (NGF) Release from Hippocampal Neurons: Evidence for a Constitutive and an Unconventional Sodium‐dependent Regulated Pathway | Q42479226 | ||
| Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome | Q42483994 | ||
| NGF deprivation of adult rat brain results in cholinergic hypofunction and selective impairments in spatial learning | Q42484664 | ||
| TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin | Q42490267 | ||
| NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat. | Q42494413 | ||
| In situ hybridization detection of trkA mRNA in brain: distribution, colocalization with p75NGFR and up-regulation by nerve growth factor | Q42501361 | ||
| Role of nerve growth factor in the expression of trkA mRNA in cultured embryonic rat basal forebrain cholinergic neurons | Q42524684 | ||
| P433 | issue | 3 | |
| P921 | main subject | gene therapy | Q213901 |
| P304 | page(s) | 267-273 | |
| P577 | publication date | 2006-01-01 | |
| P1433 | published in | Cell Transplantation | Q15761863 |
| P1476 | title | CNS gene therapy and a nexus of complexity: systems and biology at a crossroads | |
| P478 | volume | 15 |
| Q45881645 | Antisense RNA sequences modulating the ataxin-1 message: molecular model of gene therapy for spinocerebellar ataxia type 1, a dominant-acting unstable trinucleotide repeat disease |
| Q37003823 | Article Commentary: Regenerative Medicine: An Analysis of Cell Transplantation's Impact |
| Q39495849 | Brain targeting and toxicity study of odorranalectin-conjugated nanoparticles following intranasal administration |
| Q37679951 | Levodopa delivery systems: advancements in delivery of the gold standard |
| Q33726019 | Nanomedicine in the diagnosis and therapy of neurodegenerative disorders. |
| Q37538771 | Neurodegenerative disorders and nanoformulated drug development |
| Q37049189 | Neurotrophic factors in autonomic nervous system plasticity and dysfunction |
| Q51351430 | Repairing the Nervous System: A Special Issue Based on the 12th Annual American Society for Neural Therapy and Repair (ASNTR) Meeting. |
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