Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells

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Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4724927
P698PubMed publication ID14760759

P2093author name stringLi-Ning Zhang
Zhen-Guang Wang
Chun-Hong Ma
Ying-Lin Cao
Li-Hui Han
Su-Xia Liu
Wen-Sheng Sun
Fa-Liang Zhu
P2860cites workSpecific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
Nucleolar localization of hTERT protein is associated with telomerase functionQ28207128
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The prognostic molecular markers in hepatocellular carcinomaQ34668320
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Expression of p53 and C-myc genes and its clinical relevance in the hepatocellular carcinomatous and pericarcinomatous tissuesQ36308973
Expression of cloned hepatitis B virus DNA in human cell culturesQ36407411
Expression of telomerase-associated protein 1 and telomerase reverse transcriptase in hepatocellular carcinomaQ36641305
2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cellsQ38316485
Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT.Q39543159
c-Myc-mediated regulation of telomerase activity is disabled in immortalized cellsQ40799753
Ribozyme cleavage of telomerase mRNA sensitizes breast epithelial cells to inhibitors of topoisomeraseQ40812288
Dedifferentiation of human hepatocellular carcinoma up-regulates telomerase and Ki-67 expressionQ40842896
Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissuesQ41235699
Comparison of multiplex PCR, PCR-ELISA and fluorogenic 5' nuclease PCR assays for detection of plasmid-bearing virulent Yersinia enterocolitica in swine fecesQ41471093
Mechanism for the reduction of telomerase expression during muscle cell differentiationQ42502051
cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genomeQ44148234
Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA taggingQ45735381
Cloning and characterization of the promoter region of human telomerase reverse transcriptase geneQ47986055
Evidence for telomerase involvement in the angiogenesis of astrocytic tumors: expression of human telomerase reverse transcriptase messenger RNA by vascular endothelial cellsQ48839121
Growth inhibition of BEL-7404 human hepatoma cells by expression of mutant telomerase reverse transcriptase.Q52827276
Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomasQ72347543
[Effect of cell cycle on telomerase activity of hepatoma cells and its relationship with replication of hepatitis B virus]Q73407703
[Inhibition of HBV DNA replication and expression in 2.2.15 hepatoma cells infected with AFP-mediated HBX antisense RNA]Q73449219
Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1Q73726029
The correlation of TERT expression with c-myc expression in cervical cancerQ73917896
The 5'-end of hTERT mRNA is a good target for hammerhead ribozyme to suppress telomerase activityQ73938445
Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomasQ74072855
[Inhibition of telomerase activity by ribozyme targeted to human telomerase transcriptase]Q74131317
[Effects of hepatitis B virus X gene on apoptosis and the activity of telomerase in HepG(2) cells]Q74200763
Variant forms of upstream stimulatory factors (USFs) control the promoter activity of hTERT, the human gene encoding the catalytic subunit of telomeraseQ74228281
Reconstitution of hTERT restores tumorigenicity in melanoma-derived c-Myc low-expressing clonesQ74355235
TERT regulates cell survival independent of telomerase enzymatic activityQ74355604
Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissuesQ74438454
Telomerase activity in human bladder tumors and bladder washing specimensQ74590696
Telomerase reverse transcriptase mRNA expression and telomerase activity in hepatocellular carcinomaQ77329055
[Inhibition of hTR activity for suppression of lung cancer cell proliferation using antisense phosphorothioate oligonucleotides]Q77696249
Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic liversQ77799927
[Detection of telomerase activity level in human non-small-cell lung cancer]Q78820544
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)366-370
P577publication date2004-02-01
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleAntisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells
P478volume10

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cites work (P2860)
Q33866121Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinoma
Q42726362Gene therapy of liver cancer

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