| scholarly article | Q13442814 |
| P2093 | author name string | Hidetaka Yamada | |
| Yusaku Nakabeppu | |||
| Daisuke Tsuchimoto | |||
| Kunihiko Sakumi | |||
| Nona Abolhassani | |||
| Sugako Oka | |||
| Hiroko Nomaru | |||
| Zijing Sheng | |||
| P2860 | cites work | NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest | Q24306490 |
| An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress | Q24307873 | ||
| Genomic structure and chromosome location of the human mutT homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to C:G transversion | Q24313376 | ||
| Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis | Q24318724 | ||
| Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase | Q24555183 | ||
| Oxidants, antioxidants, and the degenerative diseases of aging | Q24561734 | ||
| Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage | Q28114912 | ||
| Oxidants, oxidative stress and the biology of ageing | Q28131725 | ||
| Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs | Q28143253 | ||
| Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption | Q28180293 | ||
| Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics | Q28264943 | ||
| Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases | Q28269333 | ||
| Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents | Q28367039 | ||
| A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration | Q28474016 | ||
| Perikaryal accumulation and proteolysis of neurofilament proteins in the post-mortem rat brain | Q28571322 | ||
| Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria | Q28610376 | ||
| Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue | Q28610622 | ||
| Microglia-mediated neurotoxicity: uncovering the molecular mechanisms | Q29547835 | ||
| Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen | Q31919701 | ||
| MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity. | Q33233462 | ||
| Replicating Huntington's disease phenotype in experimental animals | Q33749061 | ||
| Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates | Q34103541 | ||
| Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids. | Q34512398 | ||
| ??? | Q64819937 | ||
| Extrinsic connections of the basal ganglia | Q34570614 | ||
| Chemistry-based studies on oxidative DNA damage: formation, repair, and mutagenesis | Q34772321 | ||
| Human mitochondrial DNA is packaged with TFAM. | Q34908739 | ||
| Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling | Q35761624 | ||
| Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells. | Q36180675 | ||
| 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease. | Q36318579 | ||
| Oxidative damage in nucleic acids and Parkinson's disease. | Q36728710 | ||
| 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. | Q36934346 | ||
| Base excision repair of oxidative DNA damage and association with cancer and aging | Q37090426 | ||
| Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration | Q37237452 | ||
| Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase | Q37764544 | ||
| DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis. | Q37828633 | ||
| Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs. | Q40026363 | ||
| Microglial activation and cell death induced by the mitochondrial toxin 3-nitropropionic acid: in vitro and in vivo studies | Q40660071 | ||
| Expression of 8-oxoguanine DNA glycosylase is reduced and associated with neurofibrillary tangles in Alzheimer's disease brain. | Q42168961 | ||
| Quantitative analysis of oxidized guanine, 8-oxoguanine, in mitochondrial DNA by immunofluorescence method. | Q42455152 | ||
| Basal ganglia degeneration, myelin alterations, and enzyme inhibition induced in mice by the plant toxin 3-nitropropanoic acid | Q42464071 | ||
| Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson's disease and related neurodegenerative disorders | Q42477148 | ||
| Antibody against single-stranded DNA useful for detecting apoptotic cells recognizes hexadeoxynucleotides with various base sequences | Q42543660 | ||
| Expression of hMTH1 in the hippocampi of control and Alzheimer's disease | Q43757877 | ||
| Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1. | Q43848053 | ||
| Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors | Q44224012 | ||
| Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney. | Q44280605 | ||
| Mutator phenotype of MUTYH-null mouse embryonic stem cells. | Q44548854 | ||
| Quantifiable bradykinesia, gait abnormalities and Huntington's disease-like striatal lesions in rats chronically treated with 3-nitropropionic acid | Q45294402 | ||
| Oxidative damage to mitochondrial DNA in Huntington's disease parietal cortex | Q45299186 | ||
| Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner. | Q46590824 | ||
| MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. | Q46793098 | ||
| Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death. | Q46835805 | ||
| Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson's disease | Q48497446 | ||
| Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease | Q48910103 | ||
| Antibody against single-stranded DNA detects both programmed cell death and drug-induced apoptosis. | Q52220877 | ||
| MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis | Q80635837 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neurodegeneration | Q1755122 |
| P304 | page(s) | 4344-4361 | |
| P577 | publication date | 2012-11-12 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair | |
| P478 | volume | 122 |
| Q36616050 | 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions. |
| Q36043355 | A composite peripheral blood gene expression measure as a potential diagnostic biomarker in bipolar disorder |
| Q37702708 | Aberrant promoter methylation of hOGG1 may be associated with increased risk of non-small cell lung cancer |
| Q60046531 | Aberrant repair initiated by the adenine-DNA glycosylase does not play a role in UV-induced mutagenesis in |
| Q37375923 | Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair. |
| Q28080339 | Ageing in relation to skeletal muscle dysfunction: redox homoeostasis to regulation of gene expression |
| Q38442132 | Biological and physiological role of reactive oxygen species--the good, the bad and the ugly |
| Q26829845 | Cellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cells |
| Q34572031 | Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum |
| Q38649401 | Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice |
| Q26744443 | Connecting Malfunctioning Glial Cells and Brain Degenerative Disorders |
| Q38589212 | DNA Damage, DNA Repair, Aging, and Neurodegeneration |
| Q42774626 | Defining Trends in Global Gene Expression in Arabian Horses with Cerebellar Abiotrophy |
| Q36368301 | Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1. |
| Q35949121 | Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34 |
| Q30830038 | Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease |
| Q34556334 | MTH1 as a Chemotherapeutic Target: The Elephant in the Room. |
| Q21131242 | MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA |
| Q41159531 | MUTYH promotes oxidative microglial activation and inherited retinal degeneration. |
| Q34439252 | MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death. |
| Q98613556 | MUTYH: Not just polyposis |
| Q64245890 | Mitochondrial DNA Integrity: Role in Health and Disease |
| Q48219294 | Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes |
| Q90041357 | Mitochondrial Peptide Humanin Protects Silver Nanoparticles-Induced Neurotoxicity in Human Neuroblastoma Cancer Cells (SH-SY5Y) |
| Q26996127 | New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases |
| Q92626616 | OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model |
| Q24293107 | Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair |
| Q38232000 | Oxidative DNA damage in disease--insights gained from base excision repair glycosylase-deficient mouse models |
| Q37021524 | Oxidized dNTPs and the OGG1 and MUTYH DNA glycosylases combine to induce CAG/CTG repeat instability. |
| Q91863091 | Paricalcitol accelerates BACE1 lysosomal degradation and inhibits calpain-1 dependent neuronal loss in APP/PS1 transgenic mice |
| Q36242244 | Regulation of MUTYH, a DNA Repair Enzyme, in Renal Proximal Tubular Epithelial Cells |
| Q39087831 | Repair of 8-oxoG:A mismatches by the MUTYH glycosylase: Mechanism, metals and medicine |
| Q90826147 | Somatic mutations in the human brain: implications for psychiatric research |
| Q58697995 | Suppression of Presymptomatic Oxidative Stress and Inflammation in Neurodegeneration by Grape-Derived Polyphenols |
| Q26768287 | The Response to Oxidative DNA Damage in Neurons: Mechanisms and Disease |
| Q38498842 | The role of DNA base excision repair in brain homeostasis and disease. |
| Q99711220 | α-Lipoic Acid Maintains Brain Glucose Metabolism via BDNF/TrkB/HIF-1α Signaling Pathway in P301S Mice |
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