MicroRNA-183-5p promotes the proliferation, invasion and metastasis of human pancreatic adenocarcinoma cells

scientific article published on 5 November 2015

MicroRNA-183-5p promotes the proliferation, invasion and metastasis of human pancreatic adenocarcinoma cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OL.2015.3872
P932PMC publication ID4726923
P698PubMed publication ID26870180

P2093author name stringXiujin Li
Xiaoqian Wang
Fei Miao
Yanlin Chen
Jinhai Zhu
Nanhong Tang
P2860cites workTwenty proteins containing a C-terminal SOCS box form five structural classesQ24317684
SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardationQ24537559
Combinatorial microRNA target predictionsQ27860510
Cancer statistics, 2013Q27860762
MicroRNAs: small RNAs with a big role in gene regulationQ27860896
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
let-7 MicroRNA transfer in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor progressionQ28239424
MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitisQ28300240
The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers.Q28389376
Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancerQ28473944
MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistanceQ39852625
MicroRNA-183 regulates Ezrin expression in lung cancer cellsQ39931717
MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of diseaseQ39950193
microRNA-183 down-regulates the expression of BKCaβ1 protein that is related to the severity of chronic obstructive pulmonary disease.Q40860661
MiR-183 promotes growth of non-small cell lung cancer cells through FoxO1 inhibitionQ40930326
MicroRNAs and cancer: short RNAs go a long way.Q41906288
MicroRNA-10a is overexpressed in human pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene.Q53646044
miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway.Q54287457
Molecular pathogenesis of pancreatic cancerQ82888824
High serum miR-183 level is associated with poor responsiveness of renal cancer to natural killer cellsQ85410600
Pancreatic cancerQ29622871
Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomasQ30317493
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cellsQ30493254
Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levelsQ30502172
MicroRNA profiling implies new markers of chemoresistance of triple-negative breast cancerQ33560283
Targeting of integrin beta1 and kinesin 2alpha by microRNA 183Q33648396
Analysis of microRNAs in pancreatic fine-needle aspirates can classify benign and malignant tissuesQ33693132
Dysregulated miR-183 inhibits migration in breast cancer cells.Q33698660
MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survivalQ33748264
MicroRNA-218 inhibits cell invasion and migration of pancreatic cancer via regulating ROBO1.Q34036093
MicroRNA expression pattern in intraductal papillary mucinous neoplasmQ34063363
miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cellsQ34064071
Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinomaQ34169994
Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomasQ34983419
miRDB: an online resource for microRNA target prediction and functional annotationsQ35253629
Unique microRNAs in lung adenocarcinoma groups according to major TKI sensitive EGFR mutation statusQ35848114
MicroRNA expression aids the preoperative diagnosis of pancreatic ductal adenocarcinomaQ36032560
Prognostic and predictive relevance of microsatellite instability in colorectal cancer.Q36156497
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.Q36598372
microRNA Expression in Prospectively Collected Blood as a Potential Biomarker of Breast Cancer Risk in the BCFR.Q36647044
microRNA-183 is an oncogene targeting Dkk-3 and SMAD4 in prostate cancerQ36889693
Down-regulation of miR-221 inhibits proliferation of pancreatic cancer cells through up-regulation of PTEN, p27(kip1), p57(kip2), and PUMA.Q37278413
microRNA changes in liver tissue associated with fibrosis progression in patients with hepatitis C.Q37309033
Epidemiology of pancreatic cancer: an overviewQ37608905
SOCS proteins in development and diseaseQ38124037
MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migrationQ38338974
Wnt/β-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasionQ38894603
MicroRNA-183 suppresses retinoblastoma cell growth, invasion and migration by targeting LRP6.Q39051990
MicroRNA-424-5p suppresses the expression of SOCS6 in pancreatic cancerQ39154906
MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells.Q39221558
Metformin alters the expression profiles of microRNAs in human pancreatic cancer cellsQ39412212
MiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM9.Q39446710
MicroRNA-20a overexpression inhibited proliferation and metastasis of pancreatic carcinoma cellsQ39687562
SOCS6, down-regulated in gastric cancer, inhibits cell proliferation and colony formationQ39818291
P433issue1
P921main subjectmicroRNAQ310899
pancreatic adenocarcinomaQ18556189
P304page(s)134-140
P577publication date2015-11-05
P1433published inOncology LettersQ20640514
P1476titleMicroRNA-183-5p promotes the proliferation, invasion and metastasis of human pancreatic adenocarcinoma cells
P478volume11

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cites work (P2860)
Q48145024Candidate diagnostic miRNAs that can detect cancer in prostate biopsy.
Q52608491Clinical value and potential pathways of miR-183-5p in bladder cancer: A study based on miRNA-seq data and bioinformatics analysis.
Q91729394Downregulation of miR-183 inhibits the growth of PANC-1 pancreatic cancer cells in vitro and in vivo, and increases chemosensitivity to 5-fluorouracil and gemcitabine
Q26747871Dysregulation and functional roles of miR-183-96-182 cluster in cancer cell proliferation, invasion and metastasis
Q57299689EZH2-Mediated microRNA-139-5p Regulates Epithelial-Mesenchymal Transition and Lymph Node Metastasis of Pancreatic Cancer
Q36382688MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer.
Q89666602MicroRNA-183 in Cancer Progression
Q40542758MicroRNA-183 promotes cell proliferation via regulating programmed cell death 6 in pediatric acute myeloid leukemia
Q52649646MicroRNA-183 promotes the proliferation and metastasis of renal cell carcinoma through targeting Dickkopf-related protein 3.
Q92053325MicroRNA-183-5p: A New Potential Marker for Prostate Cancer
Q58572849MicroRNA-661 expression is upregulated in pancreatic ductal adenocarcinoma and promotes cell proliferation
Q57181868MicroRNA-transcription factor network analysis reveals miRNAs cooperatively suppress RORA in oral squamous cell carcinoma
Q59358029MicroRNAs as Potential Biomarkers in Merkel Cell Carcinoma
Q54089180Oncogenic role of miR‑183‑5p in lung adenocarcinoma: A comprehensive study of qPCR, in vitro experiments and bioinformatic analysis.
Q28079735Pancreatic Cancer, A Mis-interpreter of the Epigenetic Language
Q57821602Silencing ELMO3 Inhibits the Growth, Invasion, and Metastasis of Gastric Cancer
Q47121878Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires
Q58764036Upregulation of miR-183-5p is responsible for the promotion of apoptosis and inhibition of the epithelial-mesenchymal transition, proliferation, invasion and migration of human endometrial cancer cells by downregulating Ezrin

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