| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1002546684 |
| P356 | DOI | 10.1208/S12248-012-9413-Y |
| P932 | PMC publication ID | 3535093 |
| P698 | PubMed publication ID | 23054972 |
| P5875 | ResearchGate publication ID | 232231603 |
| P50 | author | Li Wang | Q84662003 |
| Li Wang | Q84662007 | ||
| P2093 | author name string | Douglas H Sweet | |
| P2860 | cites work | Organic anion transporter 1 (OAT1) involved in renal cell transport of aristolochic acid I | Q82206316 |
| Regulation of tissue-specific expression of renal organic anion transporters by hepatocyte nuclear factor 1 α/β and DNA methylation | Q82906618 | ||
| Association of intergenic polymorphism of organic anion transporter 1 and 3 genes with hypertension and blood pressure response to hydrochlorothiazide | Q82922415 | ||
| Organic anion transporters involved in the excretion of bestatin in the kidney | Q83316046 | ||
| Antioxidant activities, total phenolics and HPLC analyses of the phenolic compounds of extracts from common Mediterranean plants | Q83628559 | ||
| Plant secondary metabolites and gut health: the case for phenolic acids | Q84585684 | ||
| Urinary organic anion transporter protein profiles in AKI | Q84982245 | ||
| The human organic anion transporter genes OAT5 and OAT7 are transactivated by hepatocyte nuclear factor-1α (HNF-1α) | Q85007707 | ||
| Critical role of organic anion transporters 1 and 3 in kidney accumulation and toxicity of aristolochic acid I | Q85057900 | ||
| Organic anion and cation transporters occur in pairs of similar and similarly expressed genes | Q28198250 | ||
| Activation of protein kinase Czeta increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated transport | Q28574243 | ||
| Membrane transporters in drug development | Q29616802 | ||
| The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1. | Q30759685 | ||
| Suprarenal aortic clamping and reperfusion decreases medullary and cortical blood flow by decreased endogenous renal nitric oxide and PGE2 synthesis | Q33223586 | ||
| Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney | Q33544992 | ||
| Organic anion transporter 6 (Slc22a20) specificity and Sertoli cell-specific expression provide new insight on potential endogenous roles | Q33592687 | ||
| Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Calpha: accelerating endocytosis of the transporter | Q33593898 | ||
| Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4). | Q33673141 | ||
| Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models | Q33674894 | ||
| Regulation of human organic anion transporter 3 by peptide hormone bradykinin | Q33890873 | ||
| Genetic variants of human organic anion transporter 4 demonstrate altered transport of endogenous substrates | Q34211586 | ||
| Male-dominant activation of rat renal organic anion transporter 1 (Oat1) and 3 (Oat3) expression by transcription factor BCL6 | Q34243889 | ||
| Expression levels of renal organic anion transporters (OATs) and their correlation with anionic drug excretion in patients with renal diseases | Q34301057 | ||
| Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease | Q34454655 | ||
| Probenecid: an unexplained effect on cephalosporin pharmacology | Q34518155 | ||
| Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3). | Q34519533 | ||
| Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation | Q34541129 | ||
| Aristolochic acid nephropathy: a worldwide problem | Q34590610 | ||
| Effect of probenecid on the distribution and elimination of ciprofloxacin in humans | Q34720221 | ||
| Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology. | Q35015581 | ||
| Developing potent human uric acid transporter 1 (hURAT1) inhibitors | Q35070747 | ||
| Physiological and molecular characterization of aristolochic acid transport by the kidney | Q35122873 | ||
| Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury | Q35128143 | ||
| Differences in the substrate binding regions of renal organic anion transporters 1 (OAT1) and 3 (OAT3) | Q35159580 | ||
| Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis | Q35213248 | ||
| Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). | Q35446350 | ||
| Medicinal herbal extracts -- renal friend or foe? Part one: the toxicities of medicinal herbs. | Q35927418 | ||
| Organic anion transporter (Slc22a) family members as mediators of toxicity | Q36104160 | ||
| Effects of renal failure on drug transport and metabolism | Q36221336 | ||
| Effects of probenecid on furosemide kinetics and natriuresis in man | Q45118465 | ||
| Molecular cloning and characterization of a human urate transporter (hURAT1) gene promoter | Q45164570 | ||
| Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy. | Q45915832 | ||
| COX-2 inhibition attenuates endotoxin-induced downregulation of organic anion transporters in the rat renal cortex | Q46301435 | ||
| Renal organic anion transporter 1 is maldistributed and diminishes in proximal tubule cells but increases in vasculature after ischemia and reperfusion | Q46314974 | ||
| Stability and biotransformation of various dietary anthocyanins in vitro | Q46441072 | ||
| The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1. | Q46471393 | ||
| Altered renal elimination of organic anions in rats with chronic renal failure | Q46476909 | ||
| Early proximal tubule injury in experimental aristolochic acid nephropathy: functional and histological studies | Q46632318 | ||
| Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation | Q46840278 | ||
| Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction | Q48670181 | ||
| Inhibitory effects of ketoconazole and rifampin on OAT1 and OATP1B1 transport activities: considerations on drug-drug interactions | Q48677705 | ||
| In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug-drug interaction with methotrexate | Q48678324 | ||
| Human urate transporter 1 (hURAT1) mediates the transport of orotate | Q48680795 | ||
| Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice | Q48681327 | ||
| Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha. | Q52571763 | ||
| Selective toxicity of aristolochic acids I and II. | Q53335178 | ||
| Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats. | Q53575535 | ||
| Acute Renal Failure in Critically Ill Patients A Multinational, Multicenter Study | Q61363260 | ||
| In Vitro and In Vivo Assessment of Renal Drug Transporters in the Disposition of Mesna and Dimesna | Q61895092 | ||
| LFB1 and LFB3 homeoproteins are sequentially expressed during kidney development | Q67882229 | ||
| Downregulation of organic anion transporters in rat kidney under ischemia/reperfusion-induced acute [corrected] renal failure | Q79634052 | ||
| Alteration in renal organic anion transporter 1 after ischemia/reperfusion in cadaveric renal allografts | Q79803102 | ||
| Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles | Q36716533 | ||
| Oat5 and NaDC1 protein abundance in kidney and urine after renal ischemic reperfusion injury | Q37020976 | ||
| Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: pharmacological and toxicological implications | Q37616710 | ||
| Vascular calcification in animal models of CKD: A review | Q37736203 | ||
| Fluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transporters. | Q37995676 | ||
| Hepatocyte nuclear factor-4{alpha} regulates the human organic anion transporter 1 gene in the kidney | Q38303968 | ||
| 3-Monoglucuronyl-glycyrrhretinic acid is a substrate of organic anion transporters expressed in tubular epithelial cells and plays important roles in licorice-induced pseudoaldosteronism by inhibiting 11β-hydroxysteroid dehydrogenase 2. | Q39356990 | ||
| Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters | Q39549128 | ||
| Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats | Q39551923 | ||
| OAT2 catalyses efflux of glutamate and uptake of orotic acid | Q39568785 | ||
| Interactions of urate transporter URAT1 in human kidney with uricosuric drugs | Q39601954 | ||
| Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6). | Q39606380 | ||
| Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo | Q39703125 | ||
| Transport of aminopterin by human organic anion transporters hOAT1 and hOAT3: Comparison with methotrexate | Q39704871 | ||
| Organic anion transporter 3 (OAT3) and renal transport of the metal chelator 2,3-dimercapto-1-propanesulfonic acid (DMPS). | Q39726365 | ||
| Pharmacokinetic interaction between JBP485 and cephalexin in rats | Q39729383 | ||
| Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human. | Q39734079 | ||
| Effect of fenofibrate on uric acid metabolism and urate transporter 1. | Q39751749 | ||
| 5-Hydroxy-L-tryptophan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination | Q39777134 | ||
| Renal organic anion transporter-mediated drug-drug interaction between gemcabene and quinapril | Q39863663 | ||
| Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta | Q40047043 | ||
| Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation | Q40080801 | ||
| Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans | Q40141881 | ||
| Prostaglandin E2 inhibits its own renal transport by downregulation of organic anion transporters rOAT1 and rOAT3. | Q40341789 | ||
| The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids. | Q40461914 | ||
| Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells | Q40667944 | ||
| PAH extraction and estimation of plasma flow in human postischemic acute renal failure | Q41684924 | ||
| Analysis and update of the human solute carrier (SLC) gene superfamily | Q41857194 | ||
| Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8). | Q42074505 | ||
| Human organic anion transporter 3 gene is regulated constitutively and inducibly via a cAMP-response element | Q42497597 | ||
| Interactions of human organic anion transporter 1 (hOAT1) with substances associated with forensic toxicology | Q42740594 | ||
| Aristolochic acid-induced destruction of organic ion transporters and fatty acid metabolic disorder in the kidney of rats | Q42776360 | ||
| Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3. | Q42874597 | ||
| Concentration-dependent inhibitory effect of irbesartan on renal uric acid transporters | Q42927010 | ||
| Characterization of cellular uptake of perfluorooctanoate via organic anion-transporting polypeptide 1A2, organic anion transporter 4, and urate transporter 1 for their potential roles in mediating human renal reabsorption of perfluorocarboxylates | Q42966827 | ||
| Preclinical and clinical evidence for the collaborative transport and renal secretion of an oxazolidinone antibiotic by organic anion transporter 3 (OAT3/SLC22A8) and multidrug and toxin extrusion protein 1 (MATE1/SLC47A1). | Q43046056 | ||
| Interactions of human organic anion transporters with aristolochic acids | Q43052012 | ||
| Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome | Q43268945 | ||
| Inhibition of renal tubular transport of methotrexate by probenecid | Q43911534 | ||
| Stenosis-dependent role of nitric oxide and prostaglandins in chronic renal ischemia | Q43948740 | ||
| Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy | Q44057557 | ||
| Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance | Q44481064 | ||
| Acute nephrotoxicity of aristolochic acids in mice | Q44789807 | ||
| Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition | Q44792818 | ||
| Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11). | Q44977902 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 53-69 | |
| P577 | publication date | 2012-10-09 | |
| P1433 | published in | The AAPS Journal | Q10695361 |
| P1476 | title | Renal organic anion transporters (SLC22 family): expression, regulation, roles in toxicity, and impact on injury and disease | |
| P478 | volume | 15 |
| Q92285185 | A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization |
| Q36653948 | A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity. |
| Q51746824 | AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3. |
| Q48031538 | Activation of liver X receptor inhibits OCT2-mediated organic cation transport in renal proximal tubular cells. |
| Q35345065 | Antidiabetic and renoprotective effects of Cladophora glomerata Kützing extract in experimental type 2 diabetic rats: a potential nutraceutical product for diabetic nephropathy. |
| Q41878918 | Cetuximab Prevents Methotrexate-Induced Cytotoxicity in Vitro through Epidermal Growth Factor Dependent Regulation of Renal Drug Transporters. |
| Q38160088 | Clinical impact of genetic variants of drug transporters in different ethnic groups within and across regions |
| Q38981520 | Cumulative organic anion transporter-mediated drug-drug interaction potential of multiple components in salvia miltiorrhiza (danshen) preparations |
| Q37726177 | Delineating the Role of Various Factors in Renal Disposition of Digoxin through Application of Physiologically Based Kidney Model to Renal Impairment Populations. |
| Q38342677 | Drug transporters in the central nervous system |
| Q34125070 | Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transport |
| Q60955835 | Food Bioactive Compounds and Their Interference in Drug Pharmacokinetic/Pharmacodynamic Profiles |
| Q36250282 | Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters |
| Q41601248 | IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats |
| Q39695400 | Impact of the induced organic anion transporter 1 (Oat1) renal expression by furosemide on the pharmacokinetics of organic anions |
| Q42278894 | Interaction of Ethambutol with human organic cation transporters of the SLC22 family indicates potential for drug-drug interactions during antituberculosis therapy |
| Q39437374 | Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11). |
| Q38833348 | Loops and layers of post-translational modifications of drug transporters |
| Q42505239 | MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells |
| Q35768413 | Molecular Imaging of Membrane Transporters' Activity in Cancer: a Picture is Worth a Thousand Tubes |
| Q36902198 | Nedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1 |
| Q37203854 | Organic Cation Transporter 2 Overexpression May Confer an Increased Risk of Gentamicin-Induced Nephrotoxicity |
| Q50964185 | PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1. |
| Q38862493 | Posttranslational Regulation of Organic Anion Transporters by Ubiquitination: Known and Novel |
| Q35077449 | Sex-differences in renal expression of selected transporters and transcription factors in lean and obese Zucker spontaneously hypertensive fatty rats |
| Q38269878 | Small molecule membrane transporters in the mammalian podocyte: a pathogenic and therapeutic target |
| Q47198594 | The SLC22 Transporter Family: A Paradigm for the Impact of Drug Transporters on Metabolic Pathways, Signaling, and Disease. |
| Q40735408 | The role of Nedd4-1 WW domains in binding and regulating human organic anion transporter 1. |
| Q38955312 | Transcriptional regulation of human organic anion transporter 1 by B-cell CLL/lymphoma 6. |
| Q48592023 | Transporters involved in renal excretion of N-carbamoylglutamate, an orphan drug to treat inborn n-acetylglutamate synthase deficiency |
| Q33810793 | Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study |
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