Pharmacodynamics of anidulafungin against clinical Aspergillus fumigatus isolates in a nonneutropenic murine model of disseminated aspergillosis.

scientific article published on 31 October 2012

Pharmacodynamics of anidulafungin against clinical Aspergillus fumigatus isolates in a nonneutropenic murine model of disseminated aspergillosis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.01430-12
P932PMC publication ID3535895
P698PubMed publication ID23114773
P5875ResearchGate publication ID232745541

P50authorSeyedmojtaba SeyedmousaviQ40062294
Johan MoutonQ42711138
Willem MelchersQ56859383
Paul E. VerweijQ70514014
P2093author name stringRoger J M Brüggemann
P2860cites workVoriconazole versus amphotericin B for primary therapy of invasive aspergillosisQ28217179
Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of AmericaQ28263689
Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanismQ30853962
Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene.Q33613758
In vivo comparison of the pharmacodynamic targets for echinocandin drugs against Candida speciesQ33876423
Pharmacodynamics of caspofungin in a murine model of systemic candidiasis: importance of persistence of caspofungin in tissues to understanding drug activityQ34228214
Impact of cyp51A mutations on the pharmacokinetic and pharmacodynamic properties of voriconazole in a murine model of disseminated aspergillosisQ34290034
Pharmacokinetics and pharmacodynamics of posaconazole for invasive pulmonary aspergillosis: clinical implications for antifungal therapyQ34754956
Aspergillosis. Pathogenesis, clinical manifestations, and therapyQ35038459
Anidulafungin pharmacokinetics and microbial response in neutropenic mice with disseminated candidiasisQ35127833
Antifungal susceptibilities of Aspergillus fumigatus clinical isolates obtained in Nagasaki, JapanQ35666518
Clinical implications of azole resistance in Aspergillus fumigatus, The Netherlands, 2007-2009.Q35848799
Combination therapy of advanced invasive pulmonary aspergillosis in transiently neutropenic rats using human pharmacokinetic equivalent doses of voriconazole and anidulafunginQ37190801
Azole-resistance in Aspergillus: proposed nomenclature and breakpointsQ37625111
Use of Antifungal Combination Therapy: Agents, Order, and TimingQ37767359
Assessment of efficacy of antifungals in experimental models of invasive aspergillosis in an era of emerging resistance: the value of real-time quantitative PCR.Q37926156
Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A geneQ38283306
Therapeutic outcome in invasive aspergillosisQ38970340
Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failureQ42555868
Multiple-azole-resistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery.Q44318186
Combination therapy for invasive aspergillosisQ45096996
Azole-resistant central nervous system aspergillosis.Q46094844
Current role of echinocandins in the management of invasive aspergillosis.Q53217028
Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India.Q54342323
Multi-azole resistance in Aspergillus fumigatusQ56837308
Efficacy and pharmacodynamics of voriconazole combined with anidulafungin in azole-resistant invasive aspergillosisQ56993324
Multiple-Triazole–Resistant AspergillosisQ63914862
Invasive aspergillosis in critically ill patients without malignancyQ80269940
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectAspergillus fumigatusQ134359
aspergillosisQ259626
pharmacodynamicsQ725307
14-alpha sterol demethylaseQ61546270
murine modelQ122890741
P304page(s)303-308
P577publication date2012-10-31
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titlePharmacodynamics of anidulafungin against clinical Aspergillus fumigatus isolates in a nonneutropenic murine model of disseminated aspergillosis
P478volume57

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cites work (P2860)
Q49792124A new marker of echinocandins activity in an in vitro PK/PD model correlates with an animal model of Aspergillus fumigatus infection
Q40045642Animal Models for Studying Triazole Resistance in Aspergillus fumigatus.
Q35758334Aspergillus and aspergilloses in wild and domestic animals: a global health concern with parallels to human disease.
Q41441699Assessment of efficacy of antifungals against Aspergillus fumigatus: value of real-time bioluminescence imaging.
Q42638073Effects of Echinocandins in Combination with Nikkomycin Z against Invasive Candida albicans Bloodstream Isolates and the fks Mutants
Q36757621Pharmacodynamics and dose-response relationships of liposomal amphotericin B against different azole-resistant Aspergillus fumigatus isolates in a murine model of disseminated aspergillosis
Q38919690Pharmacodynamics for antifungal drug development: an approach for acceleration, risk minimization and demonstration of causality.
Q37538782Pharmacodynamics of Voriconazole against Wild-Type and Azole-Resistant Aspergillus flavus Isolates in a Nonneutropenic Murine Model of Disseminated Aspergillosis
Q35385554Pharmacodynamics of isavuconazole in an Aspergillus fumigatus mouse infection model
Q34020402Population pharmacokinetic-pharmacodynamic analysis of voriconazole and anidulafungin in adult patients with invasive aspergillosis
Q35076830Posaconazole prophylaxis in experimental azole-resistant invasive pulmonary aspergillosis.
Q48149197Triazole Resistance in Aspergillus spp.: A Worldwide Problem?

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