MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer

scientific article published on 29 January 2016

MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1026068517
P356DOI10.1186/S13046-016-0287-1
P932PMC publication ID4731927
P698PubMed publication ID26822534
P5875ResearchGate publication ID292213491

P2093author name stringTingting Li
Li Liang
Yanqing Ding
Wenting Liao
Hongli Jiao
Shuyang Wang
Yaping Ye
Qiuhua Lai
Liuqing He
Zhiyuan Xiao
Juanjuan Cai
Danling Deng
P2860cites workSFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathwayQ24309164
Identification of c-MYC as a target of the APC pathwayQ24310637
A genetic model for colorectal tumorigenesisQ27860582
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cellsQ27860717
Cancer statistics, 2013Q27860762
MicroRNA signatures in human cancersQ27860962
MicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1Q28384675
Secreted antagonists of the Wnt signalling pathwayQ29615521
A new member of the frizzled family from Drosophila functions as a Wingless receptorQ29620189
Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/β-catenin pathwayQ30301348
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environmentQ33943198
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomesQ34156430
MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms.Q34264405
Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progressionQ34728041
Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapyQ34752616
Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target.Q34758345
MicroRNA-301a promotes migration and invasion by targeting TGFBR2 in human colorectal cancerQ35005275
Reduction of miR-29c enhances pancreatic cancer cell migration and stem cell-like phenotypeQ35550094
Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal CancerQ35762264
Plasma levels of microRNA-24, microRNA-320a, and microRNA-423-5p are potential biomarkers for colorectal carcinomaQ35987115
A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destructionQ36056178
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasisQ36090214
MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasisQ36580396
Diversity of LEF/TCF action in development and diseaseQ36672669
miR-574-5p negatively regulates Qki6/7 to impact β-catenin/Wnt signalling and the development of colorectal cancerQ36745826
The genetics of hereditary colon cancerQ36972251
B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liverQ36999867
MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.Q37156452
A two-step model for colon adenoma initiation and progression caused by APC lossQ37251442
XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathwayQ37400198
Early detection of colorectal cancer: from conventional methods to novel biomarkersQ38357717
HOXB7 as a prognostic factor and mediator of colorectal cancer progressionQ38410952
Regulation of colorectal carcinoma stemness, growth, and metastasis by an miR-200c-Sox2-negative feedback loop mechanismQ39012862
MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cellsQ39021636
Tumor-suppressive microRNA-145 targets catenin δ-1 to regulate Wnt/β-catenin signaling in human colon cancer cellsQ39180219
MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cellsQ39312408
β-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/β-catenin-signaling pathwayQ39454255
Coordinated action of CK1 isoforms in canonical Wnt signaling.Q39537708
WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cellsQ39890176
APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase.Q39908039
Glucocorticoid-induced degradation of glycogen synthase kinase-3 protein is triggered by serum- and glucocorticoid-induced protein kinase and Akt signaling and controls beta-catenin dynamics and tight junction formation in mammary epithelial tumor cQ40114822
Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cellsQ40266988
Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation.Q40393503
MicroRNAs - a new generation molecular targets for treating cellular diseasesQ42759570
Diagnostic and prognostic value of the methylation status of secreted frizzled-related protein 2 in colorectal cancer.Q44048730
microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2.Q44847765
MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2.Q53080639
New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.Q54260437
Interaction of MUC1 with beta-catenin modulates the Wnt target gene cyclinD1 in H. pylori-induced gastric cancerQ80060062
P921main subjectcolorectal cancerQ188874
microRNAQ310899
P304page(s)21
P577publication date2016-01-29
P1433published inJournal of Experimental & Clinical Cancer ResearchQ13739415
P1476titleMicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer
P478volume35

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cites work (P2860)
Q33786626ANGPTL1 attenuates colorectal cancer metastasis by up-regulating microRNA-138.
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