Interleukin‑6 induces epithelial‑mesenchymal transition in human intrahepatic biliary epithelial cells

scientific article published on 22 December 2015

Interleukin‑6 induces epithelial‑mesenchymal transition in human intrahepatic biliary epithelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/MMR.2015.4706
P932PMC publication ID4732846
P698PubMed publication ID26708270
P5875ResearchGate publication ID287965697

P2093author name stringGui-Xing Jiang
Li-Ping Cao
Peng-Cheng Kang
Tian-Yu Lin
Xiang-Yu Zhong
Yun-Fu Cui
P2860cites workGrowth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial celQ40871475
Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell lineQ40921479
Activation of interleukin-6/STAT3 in rat cholangiocyte proliferation induced by lipopolysaccharideQ46467526
IL-6/STAT3/TFF3 signaling regulates human biliary epithelial cell migration and wound healing in vitroQ46752331
Biliary epithelial cell antibodies link adaptive and innate immune responses in primary sclerosing cholangitis.Q53561522
Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.Q54606882
The effect of interleukin-6 (IL-6)/gp130 signalling on biliary epithelial cell growth, in vitroQ73869458
Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: in situ and culture studyQ74165295
Interleukin-6, hepatocyte growth factor, and their receptors in biliary epithelial cells during a type I ductular reaction in mice: interactions between the periductal inflammatory and stromal cells and the biliary epitheliumQ77485741
[Role of IL-6/STAT3 in rat cholangiocyte proliferation induced by lipopolysaccharide]Q84003143
Epithelial-mesenchymal transition and its implications for fibrosisQ24302042
The basics of epithelial-mesenchymal transitionQ24652992
The epithelial-mesenchymal transition: new insights in signaling, development, and diseaseQ24683758
Epithelial-mesenchymal transitions in development and diseaseQ27860630
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasisQ28283104
Molecular requirements for epithelial-mesenchymal transition during tumor progressionQ29618960
Small proline rich protein 2a in benign and malignant liver diseaseQ30009542
Epithelial-mesenchymal transition of biliary epithelial cells in advanced liver fibrosisQ33322082
Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transitionQ33868704
IL-6-induced epithelial-mesenchymal transition promotes the generation of breast cancer stem-like cells analogous to mammosphere culturesQ34237510
Analysing protein-protein interactions with the yeast two-hybrid systemQ35040458
Regulation and function of trefoil factor family 3 expression in the biliary treeQ35103575
Signaling mechanisms of the epithelial-mesenchymal transitionQ35213019
The development and compensation of biliary cirrhosis in interleukin-6-deficient miceQ35810127
Interleukin-6: discovery of a pleiotropic cytokineQ36561156
Vimentin and epithelial-mesenchymal transition in human breast cancer--observations in vitro and in vivo.Q36857862
Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas.Q37080992
Biomarkers for epithelial-mesenchymal transitionsQ37209254
Epithelial-mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and diseaseQ37630599
The immunophysiology and apoptosis of biliary epithelial cells: primary biliary cirrhosis and primary sclerosing cholangitisQ38017976
Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathwaysQ39123866
IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathwayQ39462532
Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.Q39828317
Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretionQ40677743
P4510describes a project that usesImageJQ1659584
P433issue2
P304page(s)1563-1569
P577publication date2015-12-22
P1433published inMolecular Medicine ReportsQ26842180
P1476titleInterleukin‑6 induces epithelial‑mesenchymal transition in human intrahepatic biliary epithelial cells
P478volume13

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cites work (P2860)
Q90741842Attenuated pulmonary fibrosis in sialidase-3 knockout (Neu3-/-) mice
Q92853946Human Skin Keratinocytes on Sustained TGF-β Stimulation Reveal Partial EMT Features and Weaken Growth Arrest Responses
Q55243365Interleukin-6/STAT3 signalling regulates adipocyte induced epithelial-mesenchymal transition in breast cancer cells.
Q90626567Pathogenesis of chronic rhinosinusitis with nasal polyps: role of IL-6 in airway epithelial cell dysfunction
Q52641310Quercetin inhibits NTHi-triggered CXCR4 activation through suppressing IKKα/NF-κB and MAPK signaling pathways in otitis media.

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