Design and analysis considerations in the Ebola_Tx trial evaluating convalescent plasma in the treatment of Ebola virus disease in Guinea during the 2014-2015 outbreak

scientific article published on 14 January 2016

Design and analysis considerations in the Ebola_Tx trial evaluating convalescent plasma in the treatment of Ebola virus disease in Guinea during the 2014-2015 outbreak is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/1740774515621056
P932PMC publication ID4738238
P698PubMed publication ID26768570
P5875ResearchGate publication ID290598618

P50authorJohan van GriensvenQ28817139
Raffaella RavinettoQ28817172
Lut LynenQ42886337
Malcolm G. SempleQ45398929
Peter G. SmithQ47708456
Anja De WeggheleireQ55455280
Tansy EdwardsQ91794833
Maaike De CropQ114529794
Elhadj Ibrahima BahQ114529798
P2093author name stringJoris Menten
Yves Claeys
Ebola_Tx Consortium
Sarah Temmerman
P2860cites workThe effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysisQ27001157
Ebola virus disease in West Africa--the first 9 months of the epidemic and forward projectionsQ28248431
Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: an observational cohort studyQ33425160
Doctors and vampires in sub-Saharan Africa: ethical challenges in clinical trial researchQ34015837
The Use of Ebola Convalescent Plasma to Treat Ebola Virus Disease in Resource-Constrained Settings: A Perspective From the FieldQ34489055
Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients. International Scientific and Technical CommitteeQ34492427
Randomised controlled trials for Ebola: practical and ethical issuesQ35360159
Evaluating large-scale blood transfusion therapy for the current Ebola epidemic in LiberiaQ35661932
Passive antibody therapy for infectious diseasesQ35889582
Statistical considerations for a trial of Ebola virus disease therapeuticsQ36620043
Raising the standard for clinical care of patients with Ebola virus diseaseQ40143313
First Ebola treatment is approved by WHO.Q44093419
WHO meeting chooses untried interventions to defeat EbolaQ44093632
Blood as medicine: social meanings of blood and the success of Ebola trialsQ44096147
Large-scale convalescent blood and plasma transfusion therapy for Ebola virus diseaseQ44096329
Ebola: better protection needed for Guinean health-care workersQ44096777
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectEbola hemorrhagic feverQ51993
2014 Ebola virus epidemic in GuineaQ18160902
Orthoebolavirus zairenseQ10538943
convalescent plasmaQ105209484
P304page(s)13-21
P577publication date2016-01-14
P1433published inClinical TrialsQ5133802
P1476titleDesign and analysis considerations in the Ebola_Tx trial evaluating convalescent plasma in the treatment of Ebola virus disease in Guinea during the 2014-2015 outbreak
P478volume13

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cites work (P2860)
Q44104048Efficacy of Convalescent Plasma in Relation to Dose of Ebola Virus Antibodies
Q36305916Generation and characterization of protective antibodies to Marburg virus.
Q57092449Human Polyclonal Antibodies Produced by Transchromosomal Cattle Provide Partial Protection Against Lethal Zaire Ebolavirus Challenge in Rhesus Macaques
Q40091054Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates
Q57091968Performance of different clinical trial designs to evaluate treatments during an epidemic
Q47116619Protected to death: systematic exclusion of pregnant women from Ebola virus disease trials
Q64129697The Special Pathogens Research Network: Enabling Research Readiness
Q91024578Towards quantification of protective antibody responses by passive transfer of the 1st WHO International Standard for Ebola virus antibody in a guinea pig model
Q30238976Use of convalescent plasma in Ebola virus infection
Q57454623What motivates Ebola survivors to donate plasma during an emergency clinical trial? The case of Ebola-Tx in Guinea

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