Insight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index.

scientific article published on August 2006

Insight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1600-0625.2006.00453.X
P698PubMed publication ID16842594
P5875ResearchGate publication ID6942351

P50authorAndrew C. CatoQ67292607
P2093author name stringKhusru Asadullah
Hartmut Rehwinkel
Heike Schäcke
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Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cellsQ46812650
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Glucocorticoid induced the expression of mRNA and the secretion of lipocortin 1 in rat astrocytoma cells.Q55478804
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effectsQ24630458
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The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression.Q33780734
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Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormonesQ34083450
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Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10.Q34155771
A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effectsQ34177254
Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivoQ34435699
Post-transcriptional and nongenomic effects of glucocorticoids.Q34444573
BAG-1 family of cochaperones in the modulation of nuclear receptor action.Q34460136
DNA binding of the glucocorticoid receptor is not essential for survivalQ34469789
Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responsesQ34479244
Adverse effects of topical glucocorticosteroidsQ34480503
Dynamic remodeling of transcription complexes by molecular chaperonesQ34784636
Mechanisms involved in the side effects of glucocorticoidsQ35003894
Drug discovery for inflammatory diseasesQ35207540
The Glucocorticoid Receptor: Molecular Mechanism and New Therapeutic OpportunitiesQ35560626
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Novel ligands: fine tuning the transcriptional activity of the glucocorticoid receptorQ35892903
The glucocorticoid receptor as target for classic and novel anti-inflammatory therapyQ35976426
MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shockQ36227887
New and improved glucocorticoid receptor ligandsQ36322079
The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skinQ36326164
Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growthQ37092115
Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptorQ38293939
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)565-573
P577publication date2006-08-01
P1433published inExperimental DermatologyQ15749509
P1476titleInsight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index
P478volume15

Reverse relations

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