Oxidative stress in malaria.

scientific article published on 3 December 2012

Oxidative stress in malaria. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3390/IJMS131216346
P932PMC publication ID3546694
P698PubMed publication ID23208374
P5875ResearchGate publication ID233839538

P50authorSandro PercárioQ67701814
Michelli E S FerreiraQ85602665
P2093author name stringMichael D Green
Maria F Dolabela
Thyago C Vilhena
Bruno A Q Gomes
Danilo R Moreira
Ana Carolina M Gonçalves
Paula S O C Laurindo
P2860cites workIsolation of nitric oxide synthetase, a calmodulin-requiring enzymeQ24299059
Antimalarial activity of allicin, a biologically active compound from garlic clovesQ24545896
Evidence for reactive oxygen intermediates causing hemolysis and parasite death in malariaQ24625209
Nitric oxide and peroxynitrite in health and diseaseQ24645400
Compartmentation of redox metabolism in malaria parasitesQ27972605
Analysis of the vitamin B6 biosynthesis pathway in the human malaria parasite Plasmodium falciparumQ27972703
A genome-wide chromatin-associated nuclear peroxiredoxin from the malaria parasite Plasmodium falciparumQ27972781
Nitric oxide synthases: regulation and functionQ28247092
Ferritin: a cytoprotective antioxidant strategem of endotheliumQ28264360
Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (black cumin) in mice infected with Plasmodium yoelli nigeriensisQ28300761
Plasmodium falciparum activates endogenous Cl(-) channels of human erythrocytes by membrane oxidationQ28344722
Is ischemia involved in the pathogenesis of murine cerebral malaria?Q28350900
Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophagesQ28510921
Inhaled nitric oxide reduces endothelial activation and parasite accumulation in the brain, and enhances survival in experimental cerebral malariaQ28742640
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and uglyQ29547442
Blood-brain barrier breakdown during cerebral malaria: suicide or murder?Q50757497
Heme Induces Neutrophil Migration and Reactive Oxygen Species Generation through Signaling Pathways Characteristic of Chemotactic ReceptorsQ61695747
The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stressQ68236209
Qinghaosu-mediated oxidation in normal and abnormal erythrocytesQ69753649
Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cellsQ72345243
[Nitric oxide and sepsis]Q73411354
Ameliorative effect of curcumin on hepatotoxicity induced by chloroquine phosphateQ41932097
Early transcriptional response to chloroquine of the Plasmodium falciparum antioxidant defence in sensitive and resistant clonesQ41936651
Effect of antimalarial drugs and malaria infection on oxidative stress in pregnant womenQ42742658
Targeting glutathione by dimethylfumarate protects against experimental malaria by enhancing erythrocyte cell membrane scrambling.Q42970191
Pyrimethamine induces oxidative stress in Plasmodium yoelii 17XL-infected mice: a novel immunomodulatory mechanism of action for an old antimalarial drug?Q43145904
Natural cocoa as diet-mediated antimalarial prophylaxis.Q43203901
Glutathione protects chemokine-scavenging and antioxidative defense functions in human RBCsQ43540349
Oxidative stress and erythrocyte damage in Kenyan children with severe Plasmodium falciparum malaria.Q43622714
Protection of mice from malaria after co-administration of recombinant mouse granulocyte-macrophage colony- stimulating factor and methionine-enkephalinQ43744541
A pathogenic role of IL-12 in blood-stage murine malaria lethal strain Plasmodium berghei NK65 infection.Q43823598
Plasmodium falciparum histidine-rich protein-2 (PfHRP2) modulates the redox activity of ferri-protoporphyrin IX (FePPIX): peroxidase-like activity of the PfHRP2-FePPIX complexQ43891659
Hemozoin induces macrophage chemokine expression through oxidative stress-dependent and -independent mechanismsQ43990694
Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymesQ44120998
Apoptosis in liver during malaria: role of oxidative stress and implication of mitochondrial pathwayQ44124686
Thioredoxin reductase from the malaria mosquito Anopheles gambiaeQ44158077
Malaria-parasitized erythrocytes and hemozoin nonenzymatically generate large amounts of hydroxy fatty acids that inhibit monocyte functionsQ44189772
Primaquine-induced hemolytic anemia: formation of free radicals in rat erythrocytes exposed to 6-methoxy-8-hydroxylaminoquinolineQ44220882
Accelerated senescence of human erythrocytes cultured with Plasmodium falciparumQ44370154
Bioimmunotherapy of rodent malaria: co-treatment with recombinant mouse granulocyte-macrophage colony-stimulating factor and an enkephalin fragment peptide Tyr-Gly-GlyQ44907076
Heme inhibits human neutrophil apoptosis: involvement of phosphoinositide 3-kinase, MAPK, and NF-kappaB.Q44987487
Serum malondialdehyde levels in patients infected with Plasmodium vivax.Q45048272
Short report: Severe Plasmodium falciparum malaria in Cameroon: associated with the glutathione S-transferase M1 null genotype.Q45072530
Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria.Q45997398
Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis.Q46241543
Serum ascorbic acid concentration in patients with acute Falciparum malaria infection: possible significanceQ46411362
Clotrimazole inhibits hemoperoxidase of Plasmodium falciparum and induces oxidative stress. Proposed antimalarial mechanism of clotrimazoleQ46465773
Plasma nitrogen oxides and blood lactate concentrations in Ghanaian children with malariaQ46491371
The plasmodial apicoplast was retained under evolutionary selective pressure to assuage blood stage oxidative stressQ46582666
Relation of serum retinol to acute phase proteins and malarial morbidity in Papua New Guinea childrenQ46718265
Role of 4-hydroxynonenal in the hemozoin-mediated inhibition of differentiation of human monocytes to dendritic cells induced by GM-CSF/IL-4.Q46887905
Implication of intracellular glutathione and its related enzymes on resistance of malaria parasites to the antimalarial drug arteetherQ47601997
Decreased glutathione-S-transferase activity: diagnostic and protective role in vivax malaria.Q47825398
The thioredoxin system of the malaria parasite Plasmodium falciparum. Glutathione reduction revisited.Q47825616
Nitric oxides in plasma, urine, and cerebrospinal fluid in patients with severe falciparum malariaQ47836818
Evidence for erythrocyte lipid peroxidation in acute falciparum malariaQ47853720
Nitric oxide is neither necessary nor sufficient for resolution of Plasmodium chabaudi malaria in miceQ47871016
Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cellsQ47898188
Malaria in children: links between nutrition and immunityQ47900200
Plasmodium falciparum malaria. Ultrastructure of parasitized erythrocytes in cardiac vesselsQ47956442
Antimalarial activity of methanolic leaf extract of Piper betle L.Q47968798
Oxidative stress in children with severe malariaQ47980550
The antiplasmodial activity of Anogeissus leiocarpus and its effect on oxidative stress and lipid profile in mice infected with Plasmodium bergheiiQ47981753
Nitric oxide expression in the spleen, but not in the liver, correlates with resistance to blood-stage malaria in miceQ48000899
IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-gamma and TNF-alpha and occurs via a nitric oxide-dependent mechanismQ48001868
Origin of reactive oxygen species in erythrocytes infected with Plasmodium falciparumQ48018663
Plasma antioxidants and lipid peroxidation products in falciparum malaria.Q48019108
The treatment of animal models of malaria with iron chelators by use of a novel polymeric device for slow drug releaseQ48036871
Antiplasmodial activity of quinones: roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase.Q30888106
Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparumQ30930807
Oxidative stress of platelets and thrombocytopenia in patients with vivax malariaQ33338012
The role of reactive oxygen species on Plasmodium melanotic encapsulation in Anopheles gambiaeQ33715530
Induction of nitric oxide synthase in Anopheles stephensi by Plasmodium falciparum: mechanism of signaling and the role of parasite glycosylphosphatidylinositols.Q33769102
Gamma interferon production is critical for protective immunity to infection with blood-stage Plasmodium berghei XAT but neither NO production nor NK cell activation is criticalQ33867123
Phagocyte-derived reactive oxygen species do not influence the progression of murine blood-stage malaria infectionsQ33946665
Mechanisms of artemisinin resistance in the rodent malaria pathogen Plasmodium yoeliiQ33978709
Granulocyte-macrophage colony-stimulating factor-deficient mice have impaired resistance to blood-stage malariaQ34005519
Plasmodium berghei resists killing by reactive oxygen speciesQ34033550
Expression and characterization of three new glutathione transferases, an epsilon (AcGSTE2-2), omega (AcGSTO1-1), and theta (AcGSTT1-1) from Anopheles cracens (Diptera: Culicidae), a major Thai malaria vectorQ34109372
Flavonoids from Artemisia annua L. as antioxidants and their potential synergism with artemisinin against malaria and cancerQ34127831
Efficacy of different nitric oxide-based strategies in preventing experimental cerebral malaria by Plasmodium berghei ANKA.Q34163836
Nitric oxide: cytokine-regulation of nitric oxide in host resistance to intracellular pathogensQ34293807
Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells: a peroxisome proliferator-activated receptor-gamma-mediated effectQ34346778
Malaria parasites can develop stable resistance to artemisinin but lack mutations in candidate genes atp6 (encoding the sarcoplasmic and endoplasmic reticulum Ca2+ ATPase), tctp, mdr1, and cg10.Q34352253
Thioredoxin and glutathione system of malaria parasite Plasmodium falciparumQ34455939
Sequential induction of nitric oxide synthase by Corynebacterium parvum in different organs of the mouseQ34792100
Nitric oxide protection against murine cerebral malaria is associated with improved cerebral microcirculatory physiologyQ34833840
Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice.Q35054703
Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemiaQ35073806
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestionQ35105092
Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparumQ35144125
Potentiation of chloroquine activity against Plasmodium falciparum by the peroxidase-hydrogen peroxide systemQ35277807
History, dynamics, and public health importance of malaria parasite resistanceQ35545447
Inhibition of nitric oxide interrupts the accumulation of CD8+ T cells surrounding Plasmodium berghei-infected hepatocytesQ35555672
Nitric oxide metabolites induced in Anopheles stephensi control malaria parasite infectionQ35574449
Oxidative stress and rheology in severe malariaQ35666819
Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactionsQ35704960
Regulatory effects of iNOS on acute lung inflammatory responses in miceQ35843243
Undernutrition as an underlying cause of malaria morbidity and mortality in children less than five years old.Q35872627
Redox and antioxidant systems of the malaria parasite Plasmodium falciparumQ35896735
Antigenic diversity and immune evasion by malaria parasites.Q35946430
Induction of nitric oxide synthase and activation of signaling proteins in Anopheles mosquitoes by the malaria pigment, hemozoinQ35949804
Artemisinins: activities and actionsQ35957622
Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytesQ36058863
Role of mitochondria in toxic oxidative stress.Q36093934
Free heme toxicity and its detoxification systems in humanQ36139710
Mice deficient in interleukin-4 (IL-4) or IL-4 receptor alpha have higher resistance to sporozoite infection with Plasmodium berghei (ANKA) than do naive wild-type miceQ36226846
Elevated nitric oxide production in children with malarial anemia: hemozoin-induced nitric oxide synthase type 2 transcripts and nitric oxide in blood mononuclear cellsQ36445412
Protein S-glutathionylation in malaria parasitesQ37064654
Killing of Plasmodium yoelii by enzyme-induced products of the oxidative burstQ37098283
Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependentQ37138144
Competitive endothelial adhesion between Plasmodium falciparum isolates under physiological flow conditionsQ37370025
Suppression of Plasmodium chabaudi parasitemia is independent of the action of reactive oxygen intermediates and/or nitric oxideQ37582889
Hemozoin differentially regulates proinflammatory cytokine production in human immunodeficiency virus-seropositive and -seronegative women with placental malariaQ37623785
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cellsQ37628594
Oxidative stress and protective mechanisms in erythrocytes in relation to Plasmodium vinckei loadQ37675624
Nitric oxide for the adjunctive treatment of severe malaria: hypothesis and rationaleQ38262285
Host polymorphisms and the incidence of malaria in Ugandan childrenQ38881374
Antioxidant status and acute malaria in children in Kampala, UgandaQ38885017
High levels of inducible nitric oxide synthase mRNA are associated with increased monocyte counts in blood and have a beneficial role in Plasmodium falciparum malariaQ38945195
Parasite killing in murine malaria does not require nitric oxide productionQ39000874
The course of Plasmodium chabaudi chabaudi infections in interferon-gamma receptor deficient miceQ39000889
Artemisinin for treatment of uncomplicated falciparum malaria: is there a place for monotherapy?Q39022884
Plasmodium falciparum Malaria: reduction of endothelial cell apoptosis in vitroQ39063466
Thioredoxin reductase is essential for the survival of Plasmodium falciparum erythrocytic stagesQ39148737
Inducible nitric oxide synthase expression is increased in the brain in fatal cerebral malariaQ39210271
Regulation of intracellular glutathione levels in erythrocytes infected with chloroquine-sensitive and chloroquine-resistant Plasmodium falciparumQ39241717
Edible mushroom Agaricus sylvaticus can prevent the onset of atheroma plaques in hipercholesterolemic rabbitsQ39348869
Whole-body imaging of sequestration of Plasmodium falciparum in the rat.Q39391751
Potentiation of artemisinin activity against chloroquine-resistant Plasmodium falciparum strains by using heme modelsQ39472064
In vitro activity of riboflavin against the human malaria parasite Plasmodium falciparumQ39472582
Heme synthesis increases artemisinin-induced radical formation and cytotoxicity that can be suppressed by superoxide scavengersQ39719608
Tumor necrosis factor enhances neutrophil-mediated killing of Plasmodium falciparumQ40153660
Role of macrophages in malaria: O2 metabolite production and phagocytosis by splenic macrophages during lethal Plasmodium berghei and self-limiting Plasmodium yoelii infection in miceQ40178820
Hemozoin Increases IFN-γ-Inducible Macrophage Nitric Oxide Generation Through Extracellular Signal-Regulated Kinase- and NF-κB-Dependent PathwaysQ40628536
Cytokine and chemokine responses in a cerebral malaria-susceptible or -resistant strain of mice to Plasmodium berghei ANKA infection: early chemokine expression in the brainQ40655162
New insights into the regulation of inducible nitric oxide synthesisQ40667715
Macrophage preconditioning with synthetic malaria pigment reduces cytokine production via heme iron-dependent oxidative stressQ40834422
Nitric oxide and parasitic diseaseQ41176920
Antiplasmodial activity of [(aryl)arylsulfanylmethyl]PyridineQ41886196
Mechanism of malarial haem detoxification inhibition by chloroquineQ41907837
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectoxidative stressQ898814
malariaQ12156
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)16346-16372
P577publication date2012-12-03
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleOxidative stress in malaria
P478volume13

Reverse relations

cites work (P2860)
Q47216104A High Parasite Density Environment Induces Transcriptional Changes and Cell Death in Plasmodium falciparum Blood Stages
Q91015758A longitudinal molecular study of the ecology of malaria infections in free-ranging mandrills
Q42701944Aberrant free radical biology is a unifying theme in the etiology and pathogenesis of major human diseases
Q47716363Adjunctive therapy for severe malaria: a review and critical appraisal
Q40731621Alteration of redox status by commonly used antimalarial drugs in the north-western region of Nigeria.
Q90115459Antioxidant defense in the eyes of immunocompetent and immunosuppressed mice infected with Acanthamoeba spp
Q40078604Antioxidant defense system induced by cysteine-stabilized peptide fraction of aqueous extract of Morinda lucida leaf in selected tissues of Plasmodium berghei-infected mice.
Q37433146Antioxidant potential of a polyherbal antimalarial as an indicator of its therapeutic value
Q44784711Antiplasmodial alkaloids from the bark of Cryptocarya nigra (Lauraceae).
Q37186553Ascorbic acid co-administration with artemisinin based combination therapies in falciparum malaria
Q36079222Beneficial effect of Punica granatum peel extract on murine malaria-induced spleen injury
Q64116020Bioassay-guided isolation and identification of gametocytocidal compounds from Artemisia afra (Asteraceae)
Q38690668Cerebral malaria--clinical manifestations and pathogenesis.
Q35737756Circulating membrane-derived microvesicles in redox biology
Q27321215Clinicopathological Analysis and Multipronged Quantitative Proteomics Reveal Oxidative Stress and Cytoskeletal Proteins as Possible Markers for Severe Vivax Malaria
Q92355763Correlation of Oxidative Stress Biomarkers and Hematological Parameters in Blood Cancer Patients from Sardinia, Italy
Q89908863Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures
Q36754647DNA damage regulation and its role in drug-related phenotypes in the malaria parasites
Q33833072Dietary supplementation of chloroquine with nigella sativa seed and oil extracts in the treatment of malaria induced in mice with plasmodium berghei.
Q39207132Dysregulation of pulmonary endothelial protein C receptor and thrombomodulin in severe falciparum malaria-associated ARDS relevant to hemozoin.
Q92579988Ethyl acetate Fraction of Garcinia Mangostana L Rind Study as Antimalaria and Antioxidant in Plasmodium berghei Inoculated Mice
Q62995293Extracellular vesicles carrying lactate dehydrogenase induce suicide in increased population density of Plasmodium falciparum in vitro
Q37078258Fever of unknown origin and the role of Plasmodium vivax in Sao Paulo
Q61806309Formation primaquine-5,6-orthoquinone, the putative active and toxic metabolite of primaquine via direct oxidation in human erythrocytes
Q41553954Host genetic variations in glutathione-S-transferases, superoxide dismutases and catalase genes influence susceptibility to malaria infection in an Indian population.
Q90381959Immune responses in liver and spleen against Plasmodium yoelii pre-erythrocytic stages in Swiss mice model
Q44101448Impact of host nutritional status on infection dynamics and parasite virulence in a bird-malaria system
Q39643992In vitro antiplasmodial activities and synergistic combinations of differential solvent extracts of the polyherbal product, Nefang.
Q57784964Integrated proteomics reveals apoptosis-related mechanisms associated with placental malaria
Q52308706Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling.
Q26765808Ion Channels and Oxidative Stress as a Potential Link for the Diagnosis or Treatment of Liver Diseases
Q89997018Methanol extracts of Fagara zanthoxyloides leaves possess antimalarial effects and normalizes haematological and biochemical status of Plasmodium berghei-passaged mice
Q35619602N-acetyl cysteine and mushroom Agaricus sylvaticus supplementation decreased parasitaemia and pulmonary oxidative stress in a mice model of malaria
Q60946995Neutrophils and Malaria
Q35349261New insights into Lyme disease
Q92276876Oxidative Stress and Hemoglobin Level of Complicated and Uncomplicated Malaria Cases among Children: A Cross-Sectional Study in Kumasi Metropolis, Ghana
Q56435439Oxidative Stress: A Potential Therapeutic Target in Placental Malaria
Q37408633Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes
Q39280599Oxidative stress in malaria and artemisinin combination therapy: Pros and Cons
Q41912856Primaquine in Plasma and Methemoglobinemia in Patients with Malaria Due to Plasmodium vivax in the Brazilian Amazon Basin
Q89848925Redox Biology of Infection and Consequent Disease
Q26825559Role of the lipoperoxidation product 4-hydroxynonenal in the pathogenesis of severe malaria anemia and malaria immunodepression
Q92403858Setting the stage: The initial immune response to blood-stage parasites
Q91749957Severe oxidative stress in sickle cell disease patients with uncomplicated Plasmodium falciparum malaria in Kampala, Uganda
Q46310228Shining new light on ancient drugs: preparation and subcellular localisation of novel fluorescent analogues of Cinchona alkaloids in intraerythrocytic Plasmodium falciparum
Q47736069Strong renal expression of heat shock protein 70, high mobility group box 1, inducible nitric oxide synthase, and nitrotyrosine in mice model of severe malaria
Q47548280Susceptibility of mice strains to oxidative stress and neurotransmitter activity induced by Plasmodium berghei
Q47093575Synthetic oleanane triterpenoids enhance blood brain barrier integrity and improve survival in experimental cerebral malaria
Q92929390TRPV1 Contributes to Cerebral Malaria Severity and Mortality by Regulating Brain Inflammation
Q41730961TRPV1 antagonism by capsazepine modulates innate immune response in mice infected with Plasmodium berghei ANKA.
Q30457536Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria.
Q92091610Terminalia albida treatment improves survival in experimental cerebral malaria through reactive oxygen species scavenging and anti-inflammatory properties
Q88719545The application of the HyPer fluorescent sensor in the real-time detection of H2O2 in Babesia bovis merozoites in vitro
Q70203111The interactome of 2-Cys peroxiredoxins in Plasmodium falciparum.
Q97418375The proofreading activity of Pfprex from Plasmodium falciparum can prevent mutagenesis of the apicoplast genome by oxidized nucleotides
Q33427112Thrombocytopenia in Patients Receiving Prolonged Linezolid May be Caused by Oxidative Stress.
Q38582292Ultraviolet-visible study on acid-base equilibria of aporphine alkaloids with antiplasmodial and antioxidant activities from Alseodaphne corneri and Dehaasia longipedicellata
Q47131627iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection.

Search more.