α1A-Adrenergic receptor prevents cardiac ischemic damage through PKCδ/GLUT1/4-mediated glucose uptake

scientific article published on 29 September 2015

α1A-Adrenergic receptor prevents cardiac ischemic damage through PKCδ/GLUT1/4-mediated glucose uptake is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/10799893.2015.1091475
P932PMC publication ID4740921
P698PubMed publication ID26832303

P2093author name stringTing Shi
Dianne M Perez
Robert S Papay
P2860cites workPharmacological and ischemic preconditioning of the human myocardium: mitoK(ATP) channels are upstream and p38MAPK is downstream of PKCQ24798466
The cardiac mitochondrion: nexus of stressQ28272979
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin VQ28294206
The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouseQ28510005
Redox regulation of ischemic preconditioning is mediated by the differential activation of caveolins and their association with eNOS and GLUT-4Q28580853
HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyteQ29620367
Inhibition of protein phosphatase 1 induces apoptosis in neonatal rat cardiac myocytes: role of adrenergic receptor stimulationQ30657924
Essential activation of PKC-delta in opioid-initiated cardioprotectionQ31941069
Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytesQ33178140
Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytesQ33181618
Cellular stress responses: cell survival and cell deathQ33674213
Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.Q33944297
Remote preconditioning by infrarenal occlusion of the aorta protects the heart from infarction: a newly identified non-neuronal but PKC-dependent pathwayQ34142604
Glucose transport and apoptosisQ34170605
Optimizing cardiac energy metabolism: how can fatty acid and carbohydrate metabolism be manipulated?Q34207237
Hypoxia and glucose independently regulate the beta-adrenergic receptor-adenylate cyclase system in cardiac myocytesQ34225541
An increase in the redox state during reperfusion contributes to the cardioprotective effect of GIK solutionQ34337997
Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overloadQ34498911
Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failureQ36286936
Metabolic therapy for ischemic heart disease: the rationale for inhibition of fatty acid oxidationQ36438849
α(1A)-adrenergic receptor differentially regulates STAT3 phosphorylation through PKCϵ and PKCδ in myocytesQ36761033
Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injuryQ36852069
Mitochondrial protein kinase Cepsilon (PKCepsilon): emerging role in cardiac protection from ischaemic damageQ36979574
Hexokinase-mitochondrial interactions regulate glucose metabolism differentially in adult and neonatal cardiac myocytesQ37209189
New insights into myocardial glucose metabolism: surviving under stressQ37507460
Bioenergetics of the failing heartQ37792507
Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart.Q37831555
Cardiac and neuroprotection regulated by α(1)-adrenergic receptor subtypesQ37845379
alpha- and beta-adrenergic pathways differentially regulate cell type-specific apoptosis in rat cardiac myocytesQ40941082
Enhanced preservation of acutely ischemic myocardium and improved clinical outcomes using glucose-insulin-potassium (GIK) solutionsQ41592350
Translocation of the brain-type glucose transporter largely accounts for insulin stimulation of glucose transport in BC3H-1 myocytesQ41726185
Glucose transporters and in vivo glucose uptake in skeletal and cardiac muscle: fasting, insulin stimulation and immunoisolation studies of GLUT1 and GLUT4.Q42161174
Overexpression of alpha1B-adrenergic receptor induces left ventricular dysfunction in the absence of hypertrophyQ42461428
???Q64764692
A method to quantify glucose utilization in vivo in skeletal muscle and white adipose tissue of the anaesthetized rat.Q42849642
Hypotension, autonomic failure, and cardiac hypertrophy in transgenic mice overexpressing the alpha 1B-adrenergic receptorQ43559440
Targeted alpha(1A)-adrenergic receptor overexpression induces enhanced cardiac contractility but not hypertrophyQ43709982
Effects of trimetazidine on the contractile response of chronically dysfunctional myocardium to low-dose dobutamine in ischaemic cardiomyopathyQ43932226
Subtype specific roles of beta-adrenergic receptors in apoptosis of adult rat ventricular myocytesQ44051395
Characteristics of death of neonatal rat cardiomyocytes following hypoxia or hypoxia-reoxygenation: the association of apoptosis and cell membrane disintegrityQ44181162
Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activatorQ44513177
Intracellular ATP is required for mitochondrial apoptotic pathways in isolated hypoxic rat cardiac myocytesQ44543591
Delayed myocardial preconditioning by alpha1-adrenoceptors involves inhibition of apoptosisQ44860124
Loss of PKC-delta alters cardiac metabolismQ44995355
Ischemic preconditioning exaggerates cardiac damage in PKC-delta null miceQ44995360
Genetic enhancement of ventricular contractility protects against pressure-overload-induced cardiac dysfunction.Q45135938
alpha1A- but not alpha1B-adrenergic receptors precondition the ischemic heart by a staurosporine-sensitive, chelerythrine-insensitive mechanismQ45216536
Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat heartsQ45731326
Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI Randomized Controlled TrialQ46504683
Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelinQ46861458
Adrenergic induction of bimodal myocardial protection: signal transduction and cardiac gene reprogramming.Q51461021
Transgenic alpha1A-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival.Q54591200
An alpha1A-adrenergic-extracellular signal-regulated kinase survival signaling pathway in cardiac myocytesQ64377257
Comparative effects of hypoxia and ischemia in the isolated, blood-perfused dog heart: evaluation of left ventricular diastolic chamber distensibility and wall thicknessQ69934322
Preconditioning against myocardial dysfunction after ischemia and reperfusion by an alpha 1-adrenergic mechanismQ70474449
Alpha 1-adrenergic stimulation induces cardiac tolerance to hypoxia via induction and activation of Mn-SODQ71738201
Preconditioning of isolated rat heart is mediated by protein kinase CQ71988463
Ischaemic preconditioning is protein kinase C dependent but not through stimulation of alpha adrenergic or adenosine receptors in the isolated rat heartQ72312512
alpha 1-adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase CQ72688569
Adverse effects of constitutively active alpha(1B)-adrenergic receptors after pressure overload in mouse heartsQ74332431
"Apoptotic" myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation: analysis by immunogold electron microscopy combined with In situ nick end-labelingQ77369169
Activation of alpha1-adrenergic receptor during Ca2+ pre-conditioning elicits strong protection against Ca2+ overload injury via protein kinase C signaling pathwayQ77926995
Glucose for the heartQ77932890
The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytesQ78208404
A routine method for the estimation of lactic dehydrogenase activityQ78795693
Nicotinamide pretreatment protects cardiomyocytes against hypoxia-induced cell death by improving mitochondrial stressQ84379438
Phenylephrine preconditioning involves modulation of cardiac sarcolemmal K(ATP) current by PKC delta, AMPK and p38 MAPKQ84527251
P433issue3
P304page(s)261-270
P577publication date2015-09-29
P1433published inJournal of Receptors and Signal TransductionQ6295837
P1476titleα1A-Adrenergic receptor prevents cardiac ischemic damage through PKCδ/GLUT1/4-mediated glucose uptake
P478volume36

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cites work (P2860)
Q58577519Central Circadian Clock Regulates Energy Metabolism
Q96953417Changes in Myocardial Metabolism Preceding Sudden Cardiac Death
Q36978797Enhancement of Glucose Metabolism via PGC-1α Participates in the Cardioprotection of Chronic Intermittent Hypobaric Hypoxia
Q28067568Novel Structural Approaches to Study GPCR Regulation
Q42509859Pleiotropic Effects of Chronic Phorbol Ester Treatment to Improve Glucose Transport in Insulin-Resistant Cardiomyocytes.
Q39214039The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction.
Q51283489The role of α1-adrenergic receptors in regulating metabolism: increased glucose tolerance, leptin secretion and lipid oxidation.