TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells

scientific article published on 19 September 2015

TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.5295
P932PMC publication ID4741454
P698PubMed publication ID26418879
P5875ResearchGate publication ID282390917

P2093author name stringJian Huang
Ying Ou
Qing Yuan
Xing Liu
Weijia Liao
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
Expression of TTK, a novel human protein kinase, is associated with cell proliferationQ24300491
Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignmentQ24310028
Structural and mechanistic insights into Mps1 kinase activationQ27653321
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle functionQ27660495
Cell signaling by receptor tyrosine kinasesQ27860474
Sorafenib in advanced hepatocellular carcinomaQ27861075
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complexQ30477599
Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survivalQ33320978
Systematic analysis of essential genes reveals important regulators of G protein signalingQ33602466
The MPS1 family of protein kinasesQ33632369
Epidemiology of primary liver cancerQ33750533
Preoperative Neutrophil-to-Lymphocyte Ratio as a New Prognostic Marker in Hepatocellular Carcinoma after Curative Resection.Q33912315
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.Q34621755
TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancerQ34735167
Silencing of DLGAP5 by siRNA significantly inhibits the proliferation and invasion of hepatocellular carcinoma cellsQ35063797
Expression and function analysis of mitotic checkpoint genes identifies TTK as a potential therapeutic target for human hepatocellular carcinomaQ35182909
Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reducedQ35984652
Oncogenic B-Raf(V600E) abrogates the AKT/B-Raf/Mps1 interaction in melanoma cellsQ39145156
Anchorage-independent cell growth signature identifies tumors with metastatic potentialQ39844645
Up-regulation of DLK1 as an imprinted gene could contribute to human hepatocellular carcinoma.Q40206469
Identification of prognostic biomarkers in hepatitis B virus-related hepatocellular carcinoma and stratification by integrative multi-omics analysisQ42216727
A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.Q46915341
Expression and prognostic significance of focal adhesion kinase in hepatocellular carcinoma.Q54693008
The (un)targeted cancer kinomeQ54933459
A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violetQ71850183
Allelic loss at chromosome band 6q14 correlates with favorable prognosis in hepatocellular carcinomaQ73314730
Hepatocellular carcinoma: ESMO-ESDO Clinical Practice Guidelines for diagnosis, treatment and follow-upQ85009916
P433issue33
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)34309-34320
P577publication date2015-09-19
P1433published inOncotargetQ1573155
P1476titleTTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells
P478volume6

Reverse relations

cites work (P2860)
Q60955652A risk assessment model for the prognosis of osteosarcoma utilizing differentially expressed lncRNAs
Q96231241A robust twelve-gene signature for prognosis prediction of hepatocellular carcinoma
Q46096783Cell cycle time series gene expression data encoded as cyclic attractors in Hopfield systems.
Q96576694Classification and mutation prediction based on histopathology H&E images in liver cancer using deep learning
Q43252250Functional consequence of the p53 codon 72 polymorphism in colorectal cancer
Q64953633Gene set enrichment analysis and meta-analysis to identify six key genes regulating and controlling the prognosis of esophageal squamous cell carcinoma.
Q90421769Highlight article: Role of E2Fs and mitotic regulators controlled by E2Fs in the epithelial to mesenchymal transition
Q90380072Identification of 13 Key Genes Correlated With Progression and Prognosis in Hepatocellular Carcinoma by Weighted Gene Co-expression Network Analysis
Q47261037LncRNA-SVUGP2 suppresses progression of hepatocellular carcinoma
Q64093755Overexpression of ASPM, CDC20, and TTK Confer a Poorer Prognosis in Breast Cancer Identified by Gene Co-expression Network Analysis
Q92714341Protein kinase TTK promotes proliferation and migration and mediates epithelial-mesenchymal transition in human bladder cancer cells
Q39384713Regulation of TPD52 by antitumor microRNA-218 suppresses cancer cell migration and invasion in lung squamous cell carcinoma.
Q38707261Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines
Q38904176TC Mps1 12, a novel Mps1 inhibitor, suppresses the growth of hepatocellular carcinoma cells via the accumulation of chromosomal instability
Q58748840TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer
Q94476055The genetic association between type 2 diabetic and hepatocellular carcinomas
Q41505635Threonine and tyrosine kinase may serve as a prognostic biomarker for gallbladder cancer
Q89976987Upregulation of Thr/Tyr kinase Increases the Cancer Progression by Neurotensin and Dihydropyrimidinase-Like 3 in Lung Cancer
Q55273685miR-221 suppression through nanoparticle-based miRNA delivery system for hepatocellular carcinoma therapy and its diagnosis as a potential biomarker.
Q91790568miR-221-3p and miR-15b-5p promote cell proliferation and invasion by targeting Axin2 in liver cancer

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